Echocardiographic Measures of Left Atrial Structure and Function and the Association with Atrial Fibrillation following Acute Coronary Syndrome
Conclusion: Echocardiographic measures of LA function are independent predictors of AF following ACS.
Evaluation of LA function might improve the prognostic workup, aid in risk stratification for AF and improve selection for further examinations. (Source: Cardiology)
Source: Cardiology - April 4, 2023 Category: Cardiology Source Type: research
Hyponatremia in stable patients with advanced heart failure: association to hemodynamics and outcome
Hyponatremia is associated with worse outcomes in patients with chronic heart failure (HF) and reduced ejection fraction (HFrEF). However, it is unclear whether the worse prognosis is driven by hemodynamic derangement and how this potentially could be associated with hyponatremia. The study included 502 patients with HFrEF evaluated for advanced HF therapies, who underwent a right heart catheterization (RHC). Hyponatremia was defined as p-Na ≤136 mmol/L. The risk of all-cause mortality and a composite endpoint including mortality, left ventricular assist device (LVAD) implantation, implantation of total artificial heart ...
Source: Cardiology - March 27, 2023 Category: Cardiology Source Type: research
Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry
Introduction: Evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with Unprotected Left Main Coronary Artery (ULMCA) disease.
Methods: This was a retrospective, multicenter, observational study conducted between January 2015 to December 2019. The data on patients with ULMCA who underwent revascularization through PCI or CABG was stratified by hemoglobin level at baseline into anemic and non-anemic groups to compare in-hospital events. The pre-discharge hemoglobin following revascularization was categorized into very low ( (Source: Cardiology)
Source: Cardiology - March 24, 2023 Category: Cardiology Source Type: research
Clinical and experimental study of high mobility group box-2 and valvular calcification in elderly patients with degenerative heart valve disease
Abstract: Objective To investigate the relationship between the box-2 of the high mobility group (HMGB2) and valve calcification in senile degenerative heart valve disease(SDHVD).METHODS:According to the echocardiographic results, patients with calcified heart valves were used as the experimental group and patients without calcified heart valves were used as the control group, and blood was drawn for testing, and serum levels of HMGB2 were measured by an ELISA assay. Human heart valve interstitial cells (hVIC) cultured in vitro were randomly divided into two groups. The calcification group was cultured with a medium contai...
Source: Cardiology - March 23, 2023 Category: Cardiology Source Type: research
A nomogram for predicting 3-year mortality in patients with pulmonary hypertension due to left heart failure: A retrospective analysis of a prospective registry study
This study aimed to build a nomogram for predicting 3-year mortality and screening high-risk PH-LHF patients.
Methods: This nomogram was developed on a training cohort of 175 patients with PH-LHF diagnosed by right heart catheterization (RHC). Multivariate Cox regression was used to identify independent predictors and develop this nomogram. The median total points obtained from the nomogram were used as a cut-off point, and patients were classified into low- and high-risk groups. The concordance index (C-index) and calibration curve were utilized to ascertain the predictive accuracy and discriminative ability of the nomog...
Source: Cardiology - March 23, 2023 Category: Cardiology Source Type: research
Natural course of ECG changes and the value of multimodality imaging in acute pericarditis
Background: ECG is the initial diagnostic tool that in combination with typical symptoms often raises the suspicion of pericarditis. Echocardiography remains the first-line imaging modality for assessment of pericardial diseases, particularly effusion/tamponade, constrictive physiology, and assessment of regional wall motion abnormalities as differential diagnoses. However, cardiac CT and cardiac magnetic resonance may be necessary in complicated cases, and to identify pericardial inflammation in specific settings (atypical presentation, new onset constriction), as well as myocardial involvement and monitoring the disease ...
Source: Cardiology - March 22, 2023 Category: Cardiology Source Type: research
Antiarrhythmic Drug Therapy for Ventricular Arrhythmias: The Changing Role in the Modern Era
Antiarrhythmic drugs (AADs) are powerful tools for suppression of ventricular arrhythmias (VAs). In the modern era, the role of AADs has evolved from the primary method of prevention of sudden cardiac death to an important element of multimodality treatment of VAs that can include medications, cardiac implantable electronic devices, and catheter-based ablation procedures. In this editorial, we discuss the changing role of AADs, and how they fit into the quickly evolving arena of intervention available for VAs. (Source: Cardiology)
Source: Cardiology - March 10, 2023 Category: Cardiology Source Type: research
Pharmacotherapy in Ventricular Arrhythmias
Background
Ventricular ectopy is observed in most of the population ranging from isolated premature ventricular contractions to rapid hemodynamically unstable ventricular tachyarrhythmias like ventricular tachycardia and ventricular fibrillation. Multiple mechanisms exist for ventricular arrhythmias such as triggered activity, reentry, and automaticity. Scar-based reentry forms the basis of most malignant VA that can lead to sudden cardiac death.
Many antiarrhythmic drugs have been utilized for the suppression of ventricular arrhythmia. They are commonly classified using the Vaughan-Williams-Singh classification which di...
Source: Cardiology - March 6, 2023 Category: Cardiology Source Type: research
Lipoprotein(a) is associated with thrombus burden in culprit arteries of younger patients with ST-segment elevation myocardial infarction
Conclusions
Elevated Lp(a) is associated with greater thrombus burden in younger patients with STEMI. The finding of this observational study accords with the thrombotic and anti-fibrinolytic properties of Lp(a). A causal relationship requires verification. (Source: Cardiology)
Source: Cardiology - February 9, 2023 Category: Cardiology Source Type: research
Differentiation of Atrial Fibrillation and Atrial Fibrillation-Associated Ischemic Stroke Based on Serum Exosome miRNA-seq
Conclusions: The results indicated that miRNA expression profiles of serum exosomes in AF patients were distinct from those in AF-IS patients, and based on the distinction, AF and AF-IS patients can be distinguished. (Source: Cardiology)
Source: Cardiology - February 9, 2023 Category: Cardiology Source Type: research
