CRISPR/Cas9-mediated genome editing techniques and new breeding strategies in cereals - current status, improvements, and perspectives
Biotechnol Adv. 2023 Sep 2:108248. doi: 10.1016/j.biotechadv.2023.108248. Online ahead of print.ABSTRACTCereal crops, including triticeae species (barley, wheat, rye), as well as edible cereals (wheat, corn, rice, oat, rye, sorghum), are significant suppliers for human consumption, livestock feed, and breweries. Over the past half-century, modern varieties of cereal crops with increased yields have contributed to global food security. However, presently cultivated elite crop varieties were developed mainly for optimal environmental conditions. Thus, it has become evident that taking into account the ongoing climate changes...
Source: Biotechnology Advances - September 4, 2023 Category: Biotechnology Authors: Sunny Ahmar Goetz Hensel Damian Gruszka Source Type: research
A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond
Biotechnol Adv. 2023 Aug 31:108247. doi: 10.1016/j.biotechadv.2023.108247. Online ahead of print.ABSTRACTPsychedelic mushrooms containing psilocybin and related tryptamines have long been used for ethnomycological purposes, but emerging evidence points to the potential therapeutic value of these mushrooms to address modern neurological, psychiatric health, and related disorders. As a result, psilocybin containing mushrooms represent a re-emerging frontier for mycological, biochemical, neuroscience, and pharmacology research. This work presents crucial information related to traditional use of psychedelic mushrooms, as well...
Source: Biotechnology Advances - September 2, 2023 Category: Biotechnology Authors: Marco Pepe Mohsen Hesami Karla A de la Cerda Melissa L Perreault Tom Hsiang Andrew Maxwell Phineas Jones Source Type: research
A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond
Biotechnol Adv. 2023 Aug 31:108247. doi: 10.1016/j.biotechadv.2023.108247. Online ahead of print.ABSTRACTPsychedelic mushrooms containing psilocybin and related tryptamines have long been used for ethnomycological purposes, but emerging evidence points to the potential therapeutic value of these mushrooms to address modern neurological, psychiatric health, and related disorders. As a result, psilocybin containing mushrooms represent a re-emerging frontier for mycological, biochemical, neuroscience, and pharmacology research. This work presents crucial information related to traditional use of psychedelic mushrooms, as well...
Source: Biotechnology Advances - September 2, 2023 Category: Biotechnology Authors: Marco Pepe Mohsen Hesami Karla A de la Cerda Melissa L Perreault Tom Hsiang Andrew Maxwell Phineas Jones Source Type: research
Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment
Biotechnol Adv. 2023 Aug 29:108244. doi: 10.1016/j.biotechadv.2023.108244. Online ahead of print.ABSTRACTBeta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer occurrence. Given the advantages of high spatiotemporal resolution, high sensitivity, non-invasiveness, and being free of ionizing radiations, fluorescent imaging technology provides an excellent choice for in vivo imaging of β-gal. In this review, we detail the representative biotech advances of fluorescence imaging probes for β-gal bearing diverse fidelity-...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Bin Feng Feiyi Chu Anyao Bi Xueyan Huang Yanpeng Fang Meihui Liu Fei Chen Yanbing Li Wenbin Zeng Source Type: research
Carbohydrate flow through agricultural ecosystems: Implications for synthesis and microbial conversion of carbohydrates
Biotechnol Adv. 2023 Aug 29:108245. doi: 10.1016/j.biotechadv.2023.108245. Online ahead of print.ABSTRACTCarbohydrates are chemically and structurally diverse biomolecules, serving numerous and varied roles in agricultural ecosystems. Crops and horticulture products are inherent sources of carbohydrates that are consumed by humans and non-human animals alike; however carbohydrates are also present in other agricultural materials, such as soil and compost, human and animal tissues, milk and dairy products, and honey. The biosynthesis, modification, and flow of carbohydrates within and between agricultural ecosystems is inti...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Kristin E Low Jeffrey P Tingley Leeann Klassen Marissa L King Xiaohui Xing Caitlin Watt Shelley E R Hoover Monika Gorzelak D Wade Abbott Source Type: research
Phenylalanine in motion: A tale of an essential molecule with many faces
The objective of this review is to portray the many effects that increased phenylalanine availability has in plants under non-stressed conditions, focusing mainly on external applications. These applications include spraying and drenching whole plants with phenylalanine solutions, postharvest treatments by dipping fruit and cut flower stems, and addition of phenylalanine to cell suspensions. The results of these treatments include increased fragrance in flowers, increased aroma and pigmentation in fruit, increased production of health promoting metabolites in plant cell cultures, and increased resistance of plants, pre- an...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Anita Kumari Varun Kumar Rinat Ovadia Michal Oren-Shamir Source Type: research
Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment
Biotechnol Adv. 2023 Aug 29:108244. doi: 10.1016/j.biotechadv.2023.108244. Online ahead of print.ABSTRACTBeta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer occurrence. Given the advantages of high spatiotemporal resolution, high sensitivity, non-invasiveness, and being free of ionizing radiations, fluorescent imaging technology provides an excellent choice for in vivo imaging of β-gal. In this review, we detail the representative biotech advances of fluorescence imaging probes for β-gal bearing diverse fidelity-...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Bin Feng Feiyi Chu Anyao Bi Xueyan Huang Yanpeng Fang Meihui Liu Fei Chen Yanbing Li Wenbin Zeng Source Type: research
Carbohydrate flow through agricultural ecosystems: Implications for synthesis and microbial conversion of carbohydrates
Biotechnol Adv. 2023 Aug 29:108245. doi: 10.1016/j.biotechadv.2023.108245. Online ahead of print.ABSTRACTCarbohydrates are chemically and structurally diverse biomolecules, serving numerous and varied roles in agricultural ecosystems. Crops and horticulture products are inherent sources of carbohydrates that are consumed by humans and non-human animals alike; however carbohydrates are also present in other agricultural materials, such as soil and compost, human and animal tissues, milk and dairy products, and honey. The biosynthesis, modification, and flow of carbohydrates within and between agricultural ecosystems is inti...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Kristin E Low Jeffrey P Tingley Leeann Klassen Marissa L King Xiaohui Xing Caitlin Watt Shelley E R Hoover Monika Gorzelak D Wade Abbott Source Type: research
Phenylalanine in motion: A tale of an essential molecule with many faces
The objective of this review is to portray the many effects that increased phenylalanine availability has in plants under non-stressed conditions, focusing mainly on external applications. These applications include spraying and drenching whole plants with phenylalanine solutions, postharvest treatments by dipping fruit and cut flower stems, and addition of phenylalanine to cell suspensions. The results of these treatments include increased fragrance in flowers, increased aroma and pigmentation in fruit, increased production of health promoting metabolites in plant cell cultures, and increased resistance of plants, pre- an...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Anita Kumari Varun Kumar Rinat Ovadia Michal Oren-Shamir Source Type: research
Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment
Biotechnol Adv. 2023 Aug 29:108244. doi: 10.1016/j.biotechadv.2023.108244. Online ahead of print.ABSTRACTBeta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer occurrence. Given the advantages of high spatiotemporal resolution, high sensitivity, non-invasiveness, and being free of ionizing radiations, fluorescent imaging technology provides an excellent choice for in vivo imaging of β-gal. In this review, we detail the representative biotech advances of fluorescence imaging probes for β-gal bearing diverse fidelity-...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Bin Feng Feiyi Chu Anyao Bi Xueyan Huang Yanpeng Fang Meihui Liu Fei Chen Yanbing Li Wenbin Zeng Source Type: research
Carbohydrate flow through agricultural ecosystems: Implications for synthesis and microbial conversion of carbohydrates
Biotechnol Adv. 2023 Aug 29:108245. doi: 10.1016/j.biotechadv.2023.108245. Online ahead of print.ABSTRACTCarbohydrates are chemically and structurally diverse biomolecules, serving numerous and varied roles in agricultural ecosystems. Crops and horticulture products are inherent sources of carbohydrates that are consumed by humans and non-human animals alike; however carbohydrates are also present in other agricultural materials, such as soil and compost, human and animal tissues, milk and dairy products, and honey. The biosynthesis, modification, and flow of carbohydrates within and between agricultural ecosystems is inti...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Kristin E Low Jeffrey P Tingley Leeann Klassen Marissa L King Xiaohui Xing Caitlin Watt Shelley E R Hoover Monika Gorzelak D Wade Abbott Source Type: research
Phenylalanine in motion: A tale of an essential molecule with many faces
The objective of this review is to portray the many effects that increased phenylalanine availability has in plants under non-stressed conditions, focusing mainly on external applications. These applications include spraying and drenching whole plants with phenylalanine solutions, postharvest treatments by dipping fruit and cut flower stems, and addition of phenylalanine to cell suspensions. The results of these treatments include increased fragrance in flowers, increased aroma and pigmentation in fruit, increased production of health promoting metabolites in plant cell cultures, and increased resistance of plants, pre- an...
Source: Biotechnology Advances - August 31, 2023 Category: Biotechnology Authors: Anita Kumari Varun Kumar Rinat Ovadia Michal Oren-Shamir Source Type: research
Microbial gas fermentation technology for sustainable food protein production
Biotechnol Adv. 2023 Aug 28:108240. doi: 10.1016/j.biotechadv.2023.108240. Online ahead of print.ABSTRACTThe development of novel, sustainable, and robust food production technologies represents one of the major pillars to address the most significant challenges humanity is going to face on earth in the upcoming decades - climate change, population growth, and resource depletion. The implementation of microfoods, i.e., foods formulated with ingredients from microbial cultivation, into the food supply chain has a huge potential to contribute towards energy-efficient and nutritious food manufacturing and represents a means t...
Source: Biotechnology Advances - August 30, 2023 Category: Biotechnology Authors: Carlos Woern Lutz Grossmann Source Type: research
Controllable and biocompatible 3D bioprinting technology for microorganisms: Fundamental, environmental applications and challenges
Biotechnol Adv. 2023 Aug 28:108243. doi: 10.1016/j.biotechadv.2023.108243. Online ahead of print.ABSTRACT3D bioprinting is a new 3D manufacturing technology, that can be used to accurately distribute and load microorganisms to form microbial active materials with multiple complex functions. Based on the 3D printing of human cells in tissue engineering, 3D bioprinting technology has been developed. Although 3D bioprinting technology is still immature, it shows great potential in the environmental field. Due to the precise programming control and multi-printing pathway, 3D bioprinting technology provides a high-throughput me...
Source: Biotechnology Advances - August 30, 2023 Category: Biotechnology Authors: Tianyang Zhao Yinuo Liu Yichen Wu Minghao Zhao Yingxin Zhao Source Type: research
The role of orphan crops in the transition to nutritional quality-oriented crop improvement
Biotechnol Adv. 2023 Aug 26:108242. doi: 10.1016/j.biotechadv.2023.108242. Online ahead of print.ABSTRACTMicronutrient malnutrition is a persisting problem threatening global human health. Biofortification via metabolic engineering has been proposed as a cost-effective and short-term means to alleviate this burden. There has been a recent rise in the recognition of potential that underutilized, orphan crops can hold in decreasing malnutrition concerns. Here, we illustrate how orphan crops can serve as a medium to provide micronutrients to populations in need, whilst promoting and maintaining dietary diversity. We provide a...
Source: Biotechnology Advances - August 28, 2023 Category: Biotechnology Authors: Vincent Verbeecke Laura Cust ódio Simon Strobbe Dominique Van Der Straeten Source Type: research
