In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research
In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research
Consumption of chewing tobacco alters the serum metal contents in pregnant women at Tandojam and adjoining areas
In conclusion, consumption of chewing tobacco alters the serum metal contents in pregnant women at Tandojam and adjoining areas, Pakistan.PMID:38127179 | DOI:10.1007/s10534-023-00571-0 (Source: Biometals)
Source: Biometals - December 21, 2023 Category: Biochemistry Authors: Amna Yasin Awan Naseem Aslam Channa Shazia Perveen Solangi Lubna Noorani Source Type: research
Revealing the nuclearity of iron citrate complexes at biologically relevant conditions
Biometals. 2023 Dec 18. doi: 10.1007/s10534-023-00562-1. Online ahead of print.ABSTRACTCitric acid plays an ubiquitous role in the complexation of essential metals like iron and thus it has a key function making them biologically available. For this, iron(III) citrate complexes are considered among the most significant coordinated forms of ferric iron that take place in biochemical processes of all living organisms. Although these systems hold great biological relevance, their coordination chemistry has not been fully elucidated yet. The current study aimed to investigate the speciation of iron(III) citrate using Mössbaue...
Source: Biometals - December 19, 2023 Category: Biochemistry Authors: Maria Gracheva Zolt án Klencsár Zolt án Homonnay Ádám Solti L ászló Péter Libor Machala Petr Novak Krisztina Kov ács Source Type: research
The good, the bad, and the ugly of metals as antimicrobials
Biometals. 2023 Dec 19. doi: 10.1007/s10534-023-00565-y. Online ahead of print.ABSTRACTWe are now moving into the antimicrobial resistance (AMR) era where more antibiotic resistant bacteria are now the majority, a problem brought on by both misuse and over use of antibiotics. Unfortunately, the antibiotic development pipeline dwindled away over the past decades as they are not very profitable compounds for companies to develop. Regardless researchers over the past decade have made strides to explore alternative options and out of this we see revisiting historical infection control agents such as toxic metals. From this we ...
Source: Biometals - December 19, 2023 Category: Biochemistry Authors: Raymond J Turner Source Type: research
Revealing the nuclearity of iron citrate complexes at biologically relevant conditions
Biometals. 2023 Dec 18. doi: 10.1007/s10534-023-00562-1. Online ahead of print.ABSTRACTCitric acid plays an ubiquitous role in the complexation of essential metals like iron and thus it has a key function making them biologically available. For this, iron(III) citrate complexes are considered among the most significant coordinated forms of ferric iron that take place in biochemical processes of all living organisms. Although these systems hold great biological relevance, their coordination chemistry has not been fully elucidated yet. The current study aimed to investigate the speciation of iron(III) citrate using Mössbaue...
Source: Biometals - December 19, 2023 Category: Biochemistry Authors: Maria Gracheva Zolt án Klencsár Zolt án Homonnay Ádám Solti L ászló Péter Libor Machala Petr Novak Krisztina Kov ács Source Type: research
The good, the bad, and the ugly of metals as antimicrobials
Biometals. 2023 Dec 19. doi: 10.1007/s10534-023-00565-y. Online ahead of print.ABSTRACTWe are now moving into the antimicrobial resistance (AMR) era where more antibiotic resistant bacteria are now the majority, a problem brought on by both misuse and over use of antibiotics. Unfortunately, the antibiotic development pipeline dwindled away over the past decades as they are not very profitable compounds for companies to develop. Regardless researchers over the past decade have made strides to explore alternative options and out of this we see revisiting historical infection control agents such as toxic metals. From this we ...
Source: Biometals - December 19, 2023 Category: Biochemistry Authors: Raymond J Turner Source Type: research
Revealing the nuclearity of iron citrate complexes at biologically relevant conditions
Biometals. 2023 Dec 18. doi: 10.1007/s10534-023-00562-1. Online ahead of print.ABSTRACTCitric acid plays an ubiquitous role in the complexation of essential metals like iron and thus it has a key function making them biologically available. For this, iron(III) citrate complexes are considered among the most significant coordinated forms of ferric iron that take place in biochemical processes of all living organisms. Although these systems hold great biological relevance, their coordination chemistry has not been fully elucidated yet. The current study aimed to investigate the speciation of iron(III) citrate using Mössbaue...
Source: Biometals - December 19, 2023 Category: Biochemistry Authors: Maria Gracheva Zolt án Klencsár Zolt án Homonnay Ádám Solti L ászló Péter Libor Machala Petr Novak Krisztina Kov ács Source Type: research
Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants
This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron (Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association between LOX gene variants (rs18800449 and rs2288393) and oral submucosal fibrosis (OSMF). A total of 250 subjects were included in the study: OSMF patients (n = 50), areca nut chewers without OSMF (n = 100) and controls (n = 100). Trace metals were measured using an atomic absorption spectrophotometer, while LOX gene variants were genotyped using the tetra primer amplification refractory mutation system (tetra ARMS) polymerase chain reaction (PCR) ...
Source: Biometals - December 12, 2023 Category: Biochemistry Authors: Rafia Shah Feriha Fatima Khidri Yar Muhammad Waryah Roohi Nigar Amber Mahmood Hina Shaikh Muhammad Qasim Awan Ikram Din Ujjan Ali Muhammad Waryah Source Type: research
Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants
This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron (Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association between LOX gene variants (rs18800449 and rs2288393) and oral submucosal fibrosis (OSMF). A total of 250 subjects were included in the study: OSMF patients (n = 50), areca nut chewers without OSMF (n = 100) and controls (n = 100). Trace metals were measured using an atomic absorption spectrophotometer, while LOX gene variants were genotyped using the tetra primer amplification refractory mutation system (tetra ARMS) polymerase chain reaction (PCR) ...
Source: Biometals - December 12, 2023 Category: Biochemistry Authors: Rafia Shah Feriha Fatima Khidri Yar Muhammad Waryah Roohi Nigar Amber Mahmood Hina Shaikh Muhammad Qasim Awan Ikram Din Ujjan Ali Muhammad Waryah Source Type: research
Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants
This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron (Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association between LOX gene variants (rs18800449 and rs2288393) and oral submucosal fibrosis (OSMF). A total of 250 subjects were included in the study: OSMF patients (n = 50), areca nut chewers without OSMF (n = 100) and controls (n = 100). Trace metals were measured using an atomic absorption spectrophotometer, while LOX gene variants were genotyped using the tetra primer amplification refractory mutation system (tetra ARMS) polymerase chain reaction (PCR) ...
Source: Biometals - December 12, 2023 Category: Biochemistry Authors: Rafia Shah Feriha Fatima Khidri Yar Muhammad Waryah Roohi Nigar Amber Mahmood Hina Shaikh Muhammad Qasim Awan Ikram Din Ujjan Ali Muhammad Waryah Source Type: research
Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants
This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron (Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association between LOX gene variants (rs18800449 and rs2288393) and oral submucosal fibrosis (OSMF). A total of 250 subjects were included in the study: OSMF patients (n = 50), areca nut chewers without OSMF (n = 100) and controls (n = 100). Trace metals were measured using an atomic absorption spectrophotometer, while LOX gene variants were genotyped using the tetra primer amplification refractory mutation system (tetra ARMS) polymerase chain reaction (PCR) ...
Source: Biometals - December 12, 2023 Category: Biochemistry Authors: Rafia Shah Feriha Fatima Khidri Yar Muhammad Waryah Roohi Nigar Amber Mahmood Hina Shaikh Muhammad Qasim Awan Ikram Din Ujjan Ali Muhammad Waryah Source Type: research
Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants
This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron (Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association between LOX gene variants (rs18800449 and rs2288393) and oral submucosal fibrosis (OSMF). A total of 250 subjects were included in the study: OSMF patients (n = 50), areca nut chewers without OSMF (n = 100) and controls (n = 100). Trace metals were measured using an atomic absorption spectrophotometer, while LOX gene variants were genotyped using the tetra primer amplification refractory mutation system (tetra ARMS) polymerase chain reaction (PCR) ...
Source: Biometals - December 12, 2023 Category: Biochemistry Authors: Rafia Shah Feriha Fatima Khidri Yar Muhammad Waryah Roohi Nigar Amber Mahmood Hina Shaikh Muhammad Qasim Awan Ikram Din Ujjan Ali Muhammad Waryah Source Type: research
