Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research

In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research

Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research