Current understanding of essential trace elements in intrahepatic cholestasis of pregnancy
Biometals. 2024 Feb 17. doi: 10.1007/s10534-024-00586-1. Online ahead of print.ABSTRACTTrace elements are important components in the body and have fundamental roles in maintaining a healthy and balanced pregnancy process. Either deficiency or excess of trace elements, including selenium, iron, zinc, copper, and magnesium can lead to pregnancy complications. As a rare disorder during pregnancy of unknown aetiology, intrahepatic cholestasis of pregnancy (ICP) poses a significant risk to the fetus of perinatal mortality. ICP is a multifactorial complication of which the pathogenesis is still an enigma. Epidemiological studie...
Source: Biometals - February 17, 2024 Category: Biochemistry Authors: Dan Shan Qian Chen Yupei Xie Siyu Dai Yayi Hu Source Type: research
Current understanding of essential trace elements in intrahepatic cholestasis of pregnancy
Biometals. 2024 Feb 17. doi: 10.1007/s10534-024-00586-1. Online ahead of print.ABSTRACTTrace elements are important components in the body and have fundamental roles in maintaining a healthy and balanced pregnancy process. Either deficiency or excess of trace elements, including selenium, iron, zinc, copper, and magnesium can lead to pregnancy complications. As a rare disorder during pregnancy of unknown aetiology, intrahepatic cholestasis of pregnancy (ICP) poses a significant risk to the fetus of perinatal mortality. ICP is a multifactorial complication of which the pathogenesis is still an enigma. Epidemiological studie...
Source: Biometals - February 17, 2024 Category: Biochemistry Authors: Dan Shan Qian Chen Yupei Xie Siyu Dai Yayi Hu Source Type: research
Palladium and platinum complexes based on pyridine bases induced anticancer effectiveness via apoptosis protein signaling in cancer cells
Biometals. 2024 Feb 15. doi: 10.1007/s10534-023-00580-z. Online ahead of print.ABSTRACTPalladium and platinum complexes, especially those that include cisplatin, can be useful chemotherapeutic drugs. Alternatives that have less adverse effects and require lower dosages of treatment could be provided by complexes containing pyridine bases. The complexes [Pd(SCN)2(4-Acpy)2] (1), [Pd(N3)2(4-Acpy)2] (2) [Pd(paOH)2].2Cl (3) and [Pt(SCN)2(paO)2] (4) were prepared by self-assembly method at ambient temperature; (4-Acpy = 4-acetylpyridine and paOH = pyridine-2-carbaldehyde-oxime). The structure of complexes 1-4 was confirmed using...
Source: Biometals - February 16, 2024 Category: Biochemistry Authors: Mohamed M El-Bendary Abdullah Akhdhar Abdullah S Al-Bogami Doaa Domyati Abdulaziz A Kalantan Faisal Ay Alzahrani Samer M Alamoudi Ryan A Sheikh Ehab M M Ali Source Type: research
Palladium and platinum complexes based on pyridine bases induced anticancer effectiveness via apoptosis protein signaling in cancer cells
Biometals. 2024 Feb 15. doi: 10.1007/s10534-023-00580-z. Online ahead of print.ABSTRACTPalladium and platinum complexes, especially those that include cisplatin, can be useful chemotherapeutic drugs. Alternatives that have less adverse effects and require lower dosages of treatment could be provided by complexes containing pyridine bases. The complexes [Pd(SCN)2(4-Acpy)2] (1), [Pd(N3)2(4-Acpy)2] (2) [Pd(paOH)2].2Cl (3) and [Pt(SCN)2(paO)2] (4) were prepared by self-assembly method at ambient temperature; (4-Acpy = 4-acetylpyridine and paOH = pyridine-2-carbaldehyde-oxime). The structure of complexes 1-4 was confirmed using...
Source: Biometals - February 16, 2024 Category: Biochemistry Authors: Mohamed M El-Bendary Abdullah Akhdhar Abdullah S Al-Bogami Doaa Domyati Abdulaziz A Kalantan Faisal Ay Alzahrani Samer M Alamoudi Ryan A Sheikh Ehab M M Ali Source Type: research
Author Correction: In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2024 Feb 14. doi: 10.1007/s10534-024-00587-0. Online ahead of print.NO ABSTRACTPMID:38353813 | DOI:10.1007/s10534-024-00587-0 (Source: Biometals)
Source: Biometals - February 14, 2024 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Author Correction: In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2024 Feb 14. doi: 10.1007/s10534-024-00587-0. Online ahead of print.NO ABSTRACTPMID:38353813 | DOI:10.1007/s10534-024-00587-0 (Source: Biometals)
Source: Biometals - February 14, 2024 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Heavy metals in biological samples of cancer patients: a systematic literature review
Biometals. 2024 Feb 12. doi: 10.1007/s10534-024-00583-4. Online ahead of print.ABSTRACTThe majority of the so-called heavy metals are suspected to be involved in a number of pathologies and play a role in human carcinogenesis. Some of them (i.e. arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg) and nickel (Ni)) have been defined as carcinogens, increasing the susceptibility of tumor development and progression in humans. Moreover, Ni, Cr, Cd, Hg, and Pb together with zinc (Zn) and iron (Fe), may be capable of stimulating the progression of breast cancer and reducing a patient's sensitivity to treatment thr...
Source: Biometals - February 12, 2024 Category: Biochemistry Authors: Donatella Coradduzza Antonella Congiargiu Emanuela Azara Ismaeil Mohammed Abulkahar Mammani Maria Rosaria De Miglio Angelo Zinellu Ciriaco Carru Serenella Medici Source Type: research
Serum calcium and magnesium levels and quality of life in environmentally exposed populations in Kazakhstan
Biometals. 2024 Feb 8. doi: 10.1007/s10534-023-00579-6. Online ahead of print.ABSTRACTThe relationship between the levels of essential elements and various aspects of well-being in environmentally exposed populations still needs to be better understood. The present study aims to investigate the potential connections between serum concentrations of calcium (Ca), magnesium (Mg), and quality of life (QoL) in environmentally exposed populations in Kazakhstan. The present study involved 1881 nominally healthy individuals aged 18-52 years who were permanent residents of Abay, Borodulikha, Ust-Kamenogorsk, Kurchum, Uralsk, Aksay,...
Source: Biometals - February 8, 2024 Category: Biochemistry Authors: Geir Bj ørklund Yuliya Semenova Source Type: research
Cadmium transport by mammalian ATP-binding cassette transporters
Biometals. 2024 Feb 6. doi: 10.1007/s10534-024-00582-5. Online ahead of print.ABSTRACTCellular responses to toxic metals depend on metal accessibility to intracellular targets, reaching interaction sites, and the intracellular metal concentration, which is mainly determined by uptake pathways, binding/sequestration and efflux pathways. ATP-binding cassette (ABC) transporters are ubiquitous in the human body-usually in epithelia-and are responsible for the transfer of indispensable physiological substrates (e.g. lipids and heme), protection against potentially toxic substances, maintenance of fluid composition, and excretio...
Source: Biometals - February 6, 2024 Category: Biochemistry Authors: Frank Th évenod Wing-Kee Lee Source Type: research
Differential interactions of essential and toxic metal ions with biologically relevant phosphatidic acid and phosphatidylserine membranes
Biometals. 2024 Jan 30. doi: 10.1007/s10534-023-00576-9. Online ahead of print.ABSTRACTMetal pollutants are a growing concern due to increased use in mining and other industrial processes. Moreover, the use of metals in daily life is becoming increasingly prevalent. Metals such as manganese (Mn), cobalt (Co), and nickel (Ni) are toxic in high amounts whereas lead (Pb) and cadmium (Cd) are acutely toxic at low µM concentrations. These metals are associated with system dysfunction in humans including cancer, neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, and other cellular process'. One known but less...
Source: Biometals - January 30, 2024 Category: Biochemistry Authors: Travis Issler Kevin Sule Anna-Marie Lewrenz Elmar J Prenner Source Type: research
Antimicrobial activity of metal-based nanoparticles: a mini-review
This article presents an overview of the most current research on replacing antibiotics with NPs, including the prospects and risks involved.PMID:38286956 | DOI:10.1007/s10534-023-00573-y (Source: Biometals)
Source: Biometals - January 29, 2024 Category: Biochemistry Authors: Marharyta Hancharova Kinga Halicka-St ępień Aleksandra Dupla Anna Lesiak Jadwiga So łoducho Joanna Cabaj Source Type: research
Cadmium toxicity and autophagy: a review
Biometals. 2024 Jan 26. doi: 10.1007/s10534-023-00581-y. Online ahead of print.ABSTRACTCadmium (Cd) is an important environmental pollutant that poses a threat to human health and represents a critical component of air pollutants, food sources, and cigarette smoke. Cd is a known carcinogen and has toxic effects on the environment and various organs in humans. Heavy metals within an organism are difficult to biodegrade, and those that enter the respiratory tract are difficult to remove. Autophagy is a key mechanism for counteracting extracellular (microorganisms and foreign bodies) or intracellular (damaged organelles and p...
Source: Biometals - January 26, 2024 Category: Biochemistry Authors: Yueting Shao Liting Zheng Yiguo Jiang Source Type: research
Novel method of removing metals from estuarine water using whole microbial mats
This study addresses the limited understanding of chromium-microbial mat interactions in estuarine tidal flats. The aims were to evaluate (1) the efficiency of the microbial consortium in Cr(III) removal from seawater; (2) the elemental and mineralogical composition of the microbial mat as a natural system in the Cr removal, (3) the effects of metal on microphytobenthos, and (4) possible interactions of Cr with other metals present in the consortium. Microbial mats were exposed to Cr(III) solutions at different concentrations (2-30 mg Cr/L). Analysis such as metal concentration, organic matter content, chlorophyll a and ph...
Source: Biometals - January 25, 2024 Category: Biochemistry Authors: Natalia Gabriela Morales Pontet Carolina Fern ández Sandra Elizabeth Bott é Source Type: research
Evaluation of essential and trace metals/metalloids distribution and probable human health risk implications from branded liquid and powder milks available in Dhaka City, Bangladesh
Biometals. 2024 Jan 24. doi: 10.1007/s10534-023-00574-x. Online ahead of print.ABSTRACTThe processed forms of milk, branded liquid, and power milk available in Dhaka city, the capital of Bangladesh, were investigated for essential and trace metal/metalloids regarding nutritional and human health risk aspects. For this, the potential nutritional contribution, estimated daily intake (EDI) and non-carcinogenic risk for six different life stages with male and female categories, as well as the carcinogenic risk for children and adults of both genders, were addressed. In total, 46 branded liquid and powder milk samples were cons...
Source: Biometals - January 24, 2024 Category: Biochemistry Authors: Md Nur E Alam A K M Atique Ullah M Mozammal Hosen Md Azizul Maksud Shahidur Rahman Khan Shamima Akon Quamrun Nahar Ferdousi Jolly Shamshad B Quraishi Source Type: research
Oral arsenite exposure induces inflammation and apoptosis in pulmonary tissue: acute and chronic evaluation in young and adult mice
Biometals. 2024 Jan 25. doi: 10.1007/s10534-023-00577-8. Online ahead of print.ABSTRACTInorganic arsenic is a well-known environmental toxicant, and exposure to this metalloid is strongly linked with severe and extensive toxic effects in various organs including the lungs. In the present study, we aimed to investigate the acute and chronic effects of arsenite exposure on pulmonary tissue in young and adult mice. In brief, young and adult female Balb/C mice were exposed to 3 and 30 ppm arsenite daily via drinking water for 30 and 90 days. Subsequently, the animals were sacrificed and various histological and immunohistochem...
Source: Biometals - January 24, 2024 Category: Biochemistry Authors: Samata Pradhan Syed Afroz Ali Mahesh Rachamalla Som Niyogi Ashok Kumar Datusalia Source Type: research
