In Memoriam Pierre Cornelis 1949-2023
Biometals. 2024 Feb;37(1):1-2. doi: 10.1007/s10534-023-00575-w.NO ABSTRACTPMID:38231418 | DOI:10.1007/s10534-023-00575-w (Source: Biometals)
Source: Biometals - January 17, 2024 Category: Biochemistry Authors: Isabelle Schalk Isabelle Michaud-Soret Source Type: research
Post-exposure self-recovery reverses oxidative stress, ameliorates pathology and neurotransmitters imbalance and rescues spatial memory after time-dependent aluminum exposure in rat brain
Biometals. 2024 Jan 17. doi: 10.1007/s10534-023-00570-1. Online ahead of print.ABSTRACTAluminum is a potent neurotoxin, responsible for memory impairment and cognitive dysfunction. The neurotoxic effect of aluminum on cognitive impairment is well documented, however, exposure to aluminum in a time-dependent manner and post-exposure self-recovery still needs to be elaborated. This research aimed to (1) study the time-dependent effect of aluminum exposure by administering a total dose of 5850 mg/kg of Al over two different time periods: 30 and 45 days (130 and 195 mg/kg of AlCl3 respectively), and (2) study 20 days post-expo...
Source: Biometals - January 17, 2024 Category: Biochemistry Authors: Humna Asghar Alveena Siddiqui Laraib Batool Zehra Batool Touqeer Ahmed Source Type: research
Cadmium toxicity: its' uptake and retaliation by plant defence system and ja signaling
Biometals. 2024 Jan 11. doi: 10.1007/s10534-023-00569-8. Online ahead of print.ABSTRACTCadmium (Cd+2) renders multifarious environmental stresses and highly toxic to nearly all living organisms including plants. Cd causes toxicity by unnecessary augmentation of ROS that targets essential molecules and fundamental processes in plants. In response, plants outfitted a repertory of mechanisms to offset Cd toxicity. The main elements of these are Cd chelation, sequestration into vacuoles, and adjustment of Cd uptake by transporters and escalation of antioxidative mechanism. Signal molecules like phytohormones and reactive oxyge...
Source: Biometals - January 11, 2024 Category: Biochemistry Authors: Shruti Kaushik Alok Ranjan Anmol Sidhu Anil Kumar Singh Geetika Sirhindi Source Type: research
Association between circulating micronutrient pattern, glycemic control, and insulin resistance in type 2 diabetes mellitus
Biometals. 2024 Jan 10. doi: 10.1007/s10534-023-00568-9. Online ahead of print.ABSTRACTThe circulating micronutrient pattern in type 2 diabetes mellitus (T2DM) may impact glycemic control and insulin resistance; however, there is a scarcity of studies that have evaluated the circulating micronutrient pattern in the T2DM population. Therefore, our objective was to identify circulating micronutrient pattern and their association with markers of glycemic control and insulin resistance in individuals with T2DM. We developed a cross-sectional observational study involving adults with T2DM in Sergipe, Brazil. We assessed plasma ...
Source: Biometals - January 10, 2024 Category: Biochemistry Authors: Ramara Kadija Fonseca Santos Silv ânio Silvério Lopes da Costa Samir Hip ólito Dos Santos Vivianne de Sousa Rocha Ana Mara de Oliveira E Silva Liliane Viana Pires Source Type: research
Prenatal double-hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido-nitrergic stress and endocrine perturbations
This study investigated the impacts of perinatal Al chloride (AlCl3) and Cd chloride (CdCl2) co-exposures on neuroendocrine functions in mice offspring during postnatal life. The study comprised of four pregnant experimental groups. Group 1 received AlCl3 (10 mg/kg), group 2 were administered CdCl2 (1.5 mg/kg), while group 3 received both AlCl3 (10 mg/kg) and CdCl2 (1.5 mg/kg) (AlCl3+CdCl2), and group 4 received saline (10 mL/kg) only and served as control group. All experimental animals were chemically exposed once daily from gestation days 7-20. Upon delivery, male pups were regrouped based on maternal chemical exposure ...
Source: Biometals - January 8, 2024 Category: Biochemistry Authors: Emmanuel Okhue Helen Ejiro Kadiri Patrick Chukwuyenum Ichipi-Ifukor Benneth Ben-Azu Samuel Ogheneovo Asagba Fidelis Ifeakachuku Achuba John Chukwuma Oyem Source Type: research
Prenatal double-hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido-nitrergic stress and endocrine perturbations
This study investigated the impacts of perinatal Al chloride (AlCl3) and Cd chloride (CdCl2) co-exposures on neuroendocrine functions in mice offspring during postnatal life. The study comprised of four pregnant experimental groups. Group 1 received AlCl3 (10 mg/kg), group 2 were administered CdCl2 (1.5 mg/kg), while group 3 received both AlCl3 (10 mg/kg) and CdCl2 (1.5 mg/kg) (AlCl3+CdCl2), and group 4 received saline (10 mL/kg) only and served as control group. All experimental animals were chemically exposed once daily from gestation days 7-20. Upon delivery, male pups were regrouped based on maternal chemical exposure ...
Source: Biometals - January 8, 2024 Category: Biochemistry Authors: Emmanuel Okhue Helen Ejiro Kadiri Patrick Chukwuyenum Ichipi-Ifukor Benneth Ben-Azu Samuel Ogheneovo Asagba Fidelis Ifeakachuku Achuba John Chukwuma Oyem Source Type: research
Prenatal double-hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido-nitrergic stress and endocrine perturbations
This study investigated the impacts of perinatal Al chloride (AlCl3) and Cd chloride (CdCl2) co-exposures on neuroendocrine functions in mice offspring during postnatal life. The study comprised of four pregnant experimental groups. Group 1 received AlCl3 (10 mg/kg), group 2 were administered CdCl2 (1.5 mg/kg), while group 3 received both AlCl3 (10 mg/kg) and CdCl2 (1.5 mg/kg) (AlCl3+CdCl2), and group 4 received saline (10 mL/kg) only and served as control group. All experimental animals were chemically exposed once daily from gestation days 7-20. Upon delivery, male pups were regrouped based on maternal chemical exposure ...
Source: Biometals - January 8, 2024 Category: Biochemistry Authors: Emmanuel Okhue Helen Ejiro Kadiri Patrick Chukwuyenum Ichipi-Ifukor Benneth Ben-Azu Samuel Ogheneovo Asagba Fidelis Ifeakachuku Achuba John Chukwuma Oyem Source Type: research
Cadmium induces microcytosis and anisocytosis without anaemia in hypertensive rats
This study, therefore, aims to evaluate the effects of Cd2+ on blood pressure (BP) and haematological indices in the Sprague-Dawley rat model. Three cohorts (n = 10 each) of control and Cd2+-fed male Sprague-Dawley rats were selected. Cd2+-exposed rats received 2.5 or 5 mg/kg b.w. cadmium chloride via gavage thrice-weekly for eight weeks, while control animals received tap water. BP and flow were measured non-invasively from rat tails twice-weekly using a CODA machine, while weights were measured thrice-weekly. Haematological indices were assessed using the Cell-Dyn Emerald Haematology Analyzer. Data were reported as mean ...
Source: Biometals - January 7, 2024 Category: Biochemistry Authors: Garsha McCalla Paul D Brown Chukwuemeka Nwokocha Source Type: research
In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research
In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research
In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00566-x. Online ahead of print.ABSTRACTSiderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally performed using non-ribosomal peptide synthetase (NRPS) or NRPS-independent siderophore (NIS) enzymes. Vibrio parahaemolyticus secretes its cognate siderophore vibrioferrin under iron-starvation conditions. Vibrioferrin is a dehydrated condensate composed of α-ketoglutarate, L-alanine, aminoethanol, and citrate, and pvsA (the gene encoding the...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Tomotaka Tanabe Hidemichi Mitome Katsushiro Miyamoto Kazuki Akira Hiroshi Tsujibo Koji Tomoo Kenjiro Nagaoka Tatsuya Funahashi Source Type: research
In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use
Biometals. 2023 Dec 22. doi: 10.1007/s10534-023-00572-z. Online ahead of print.ABSTRACTCopper has well-documented antibacterial effects but few have evaluated it after prolonged use and against bacteria and viruses. Coupons from three copper formulations (solid, thermal coating, and decal applications) and carbon steel controls were subjected to 200 rounds simulated cleaning using a Wiperator™ and either an accelerated hydrogen peroxide, quaternary ammonium, or artificial sweat products. Antibacterial activity against S. aureus and P. aeruginosa was then evaluated using a modified Environmental Protection Agency protocol...
Source: Biometals - December 22, 2023 Category: Biochemistry Authors: Marthe K Charles Teresa C Williams Davood Nakhaie Tracey Woznow Billie Velapatino Ana C Lorenzo-Leal Horacio Bach Elizabeth A Bryce Edouard Asselin Source Type: research
