The effect of crocin-selenium nanoparticles on the cognition and oxidative stress markers of multiple sclerosis patients: a randomized triple-blinded placebo-controlled clinical trial
Biometals. 2023 Nov 2. doi: 10.1007/s10534-023-00548-z. Online ahead of print.ABSTRACTThe prevalence of cognitive impairment in multiple sclerosis (MS) patients is estimated to be approximately 40-60%. There is an increasing body of evidence regarding the impact of both selenium and crocin as antioxidant agents on cognitive function. In the present study, for the first time, we investigated the effect of crocin-selenium nanoparticles (Cor@SeNs) on cognitive function and oxidative stress markers in MS patients. A triple-blind randomized clinical trial was conducted among 60 MS patients. The participants were randomly divide...
Source: Biometals - November 2, 2023 Category: Biochemistry Authors: Nasim Rezaeimanesh Pegah Rafiee Roghayyeh Saeedi Pegah Khosravian Mohammad Ali Sahraian Sharareh Eskandarieh Abdorreza Naser Moghadasi Soodeh Razeghi Jahromi Source Type: research

Antifungal potential of the new copper(II)-theophylline/1,10-phenanthroline complex against drug-resistant Candida species
Biometals. 2023 Nov 2. doi: 10.1007/s10534-023-00549-y. Online ahead of print.ABSTRACTCandida spp. are the commonest fungal pathogens worldwide. Antifungal resistance is a problem that has prompted the discovery of novel anti-Candida drugs. Herein, 25 compounds, some of them containing copper(II), cobalt(II) and manganese(II) ions, were initially evaluated for inhibiting the growth of reference strains of Candida albicans and Candida tropicalis. Eight (32%) of the compounds inhibited the proliferation of these yeasts, displaying minimum inhibitory concentrations (MICs) ranging from 31.25 to 250 μg/mL and minimum fungicida...
Source: Biometals - November 2, 2023 Category: Biochemistry Authors: Heloisa F Frota Carolline M A Lorentino Pedro F Barbosa L ívia S Ramos Iuri C Barcellos Lucas Giovanini Lucieri O P Souza Simone S C Oliveira Olufunso O Abosede Adeniyi S Ogunlaja Matheus M Pereira Marta H Branquinha Andr é L S Santos Source Type: research

Phytogenic nanoparticles: synthesis, characterization, and their roles in physiology and biochemistry of plants
Biometals. 2023 Nov 2. doi: 10.1007/s10534-023-00542-5. Online ahead of print.ABSTRACTResearchers are swarming to nanotechnology because of its potentially game-changing applications in medicine, pharmaceuticals, and agriculture. This fast-growing, cutting-edge technology is trying different approaches for synthesizing nanoparticles of specific sizes and shapes. Nanoparticles (NPs) have been successfully synthesized using physical and chemical processes; there is an urgent demand to establish environmentally acceptable and sustainable ways for their synthesis. The green approach of nanoparticle synthesis has emerged as a s...
Source: Biometals - November 2, 2023 Category: Biochemistry Authors: Mohammad Shiraz Havza Imtiaz Ameer Azam Shamsul Hayat Source Type: research

Cyanobacterial blooms, iron, and environmental pollutants
Biometals. 2023 Nov 1. doi: 10.1007/s10534-023-00553-2. Online ahead of print.ABSTRACTIron determines the abundance and diversity of life and controls primary production in numerous aqueous environments. Over the past decades, the availability of this metal in natural waters has decreased. Iron deficiency can apply a selective pressure on microbial aquatic communities. Each aquatic organism has their individual requirements for iron and pathways for metal acquisition, despite all having access to the common pool of iron. Cyanobacteria, a photosynthesizing bacterium that can accumulate and form so-called 'algal blooms', hav...
Source: Biometals - November 1, 2023 Category: Biochemistry Authors: Andrew J Ghio Elizabeth D Hilborn Source Type: research

Design and preparation of Ti-xFe antibacterial titanium alloys based on micro-area potential difference
Biometals. 2023 Oct 31. doi: 10.1007/s10534-023-00551-4. Online ahead of print.ABSTRACTFe was selected as an alloying element for the first time to prepare a new antibacterial titanium alloy based on micro-area potential difference (MAPD) antibacterial mechanism. The microstructure, the corrosion resistance, the mechanical properties, the antibacterial properties and the cell biocompatibility have been investigated in detail by optical microscopy, scanning electron microscopy, electrochemical testing, mechanical property test, plate count method and cell toxicity measurement. It was demonstrated that heat treatment had a s...
Source: Biometals - October 31, 2023 Category: Biochemistry Authors: Yanchun Xie Shenshen Cui Jiali Hu Hailong Yu Anwu Xuan Yongcun Wei Yi Lian Jinhua Wu Weinan Du Erlin Zhang Source Type: research

Design and preparation of Ti-xFe antibacterial titanium alloys based on micro-area potential difference
Biometals. 2023 Oct 31. doi: 10.1007/s10534-023-00551-4. Online ahead of print.ABSTRACTFe was selected as an alloying element for the first time to prepare a new antibacterial titanium alloy based on micro-area potential difference (MAPD) antibacterial mechanism. The microstructure, the corrosion resistance, the mechanical properties, the antibacterial properties and the cell biocompatibility have been investigated in detail by optical microscopy, scanning electron microscopy, electrochemical testing, mechanical property test, plate count method and cell toxicity measurement. It was demonstrated that heat treatment had a s...
Source: Biometals - October 31, 2023 Category: Biochemistry Authors: Yanchun Xie Shenshen Cui Jiali Hu Hailong Yu Anwu Xuan Yongcun Wei Yi Lian Jinhua Wu Weinan Du Erlin Zhang Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri
Biometals. 2023 Oct 24. doi: 10.1007/s10534-023-00550-5. Online ahead of print.ABSTRACTSoil pollution by metals and metalloids as a consequence of anthropogenic industrialisation exerts a seriously damaging impact on ecosystems. However, certain plant species, termed hyperaccumulators, are able to accumulate extraordinarily high concentrations of these metal(loid)s in their aboveground tissues. Such hyperaccumulation of metal(loid)s is known to act as a defence against various antagonists, such as herbivores and pathogens. We investigated the influences of metal(loid)s on potential defence traits, such as foliar elemental,...
Source: Biometals - October 24, 2023 Category: Biochemistry Authors: Rocky Putra Max T ölle Ute Kr ämer Caroline M üller Source Type: research

Some remarks on the biological application of gold(III) complexes
Biometals. 2023 Oct 19. doi: 10.1007/s10534-023-00545-2. Online ahead of print.ABSTRACTGold(III) complexes are widely studied as antitumor agents and show good results. The interaction with biologically active thiols (thiomalate, cysteine, glutathione (GSH) and human serum albumin) of a number of gold(III) complexes with N-containing polydentate ligands in aqueous solution with pH 7.4 and 0.2 M NaCl was studied. Complexes with 1,10-phenanthroline and 2,2'-bipyridyl, Au(phen)(OH)2+ and Au(bipy)(OH)2+, react fast with an excess of any of these thiols and in less than a few seconds transform into gold(I) bis-thiolate complexe...
Source: Biometals - October 19, 2023 Category: Biochemistry Authors: Igor V Mironov Viktoria Yu Kharlamova Eugenia V Makotchenko Source Type: research

Some remarks on the biological application of gold(III) complexes
Biometals. 2023 Oct 19. doi: 10.1007/s10534-023-00545-2. Online ahead of print.ABSTRACTGold(III) complexes are widely studied as antitumor agents and show good results. The interaction with biologically active thiols (thiomalate, cysteine, glutathione (GSH) and human serum albumin) of a number of gold(III) complexes with N-containing polydentate ligands in aqueous solution with pH 7.4 and 0.2 M NaCl was studied. Complexes with 1,10-phenanthroline and 2,2'-bipyridyl, Au(phen)(OH)2+ and Au(bipy)(OH)2+, react fast with an excess of any of these thiols and in less than a few seconds transform into gold(I) bis-thiolate complexe...
Source: Biometals - October 19, 2023 Category: Biochemistry Authors: Igor V Mironov Viktoria Yu Kharlamova Eugenia V Makotchenko Source Type: research

Some remarks on the biological application of gold(III) complexes
Biometals. 2023 Oct 19. doi: 10.1007/s10534-023-00545-2. Online ahead of print.ABSTRACTGold(III) complexes are widely studied as antitumor agents and show good results. The interaction with biologically active thiols (thiomalate, cysteine, glutathione (GSH) and human serum albumin) of a number of gold(III) complexes with N-containing polydentate ligands in aqueous solution with pH 7.4 and 0.2 M NaCl was studied. Complexes with 1,10-phenanthroline and 2,2'-bipyridyl, Au(phen)(OH)2+ and Au(bipy)(OH)2+, react fast with an excess of any of these thiols and in less than a few seconds transform into gold(I) bis-thiolate complexe...
Source: Biometals - October 19, 2023 Category: Biochemistry Authors: Igor V Mironov Viktoria Yu Kharlamova Eugenia V Makotchenko Source Type: research