Electrochemistry detection of estrogenic effect: Regulation of de novo purine synthesis and catabolism by gibberellin and fulvestrant
In this study, the estrogenic effect induced by gibberellin with ERα-dependent manner was found by E-screen and western blot methods, and the electrochemical signals of MCF-7 cells regulated by gibberellin and fulvestrant were investigated. The results showed that the electrochemical signals of MCF-7 cells were increased by gibberellin, while reduced by fulvestrant significantly, and displayed an extremely sensitive response to the effects of estrogenic effect induced by ERα agonist and antagonist. Western blot results showed that the expressions of phosphoribosyl pyrophosphate amidotransferase and hypoxanthine nucleotid...
Source: Bioelectrochemistry - December 31, 2023 Category: Biochemistry Authors: Yuhang Wang Shuo Zhao Shuhong Wang Jing Zhang Yanli Zhao Cai Ye Zhiyu Zhao Jinlian Li Hongkuan Shen Dongmei Wu Source Type: research
The influence of SRB on corrosion behavior of Cu-based medium-entropy alloy coating sprayed by HVOF
In this study, a novel Cu-based (Cu55Al20Ni12Ti8Si5, at.%) medium-entropy alloy (MEA) coating was prepared by high-velocity oxygen-fuel (HVOF) spraying technology. Thermo-Calc was employed to simulate the phase diagram of the alloy system. Phase composition and microstructure of the as-sprayed coating were characterized by means of XRD, FESEM, TEM and STEM/EDX. The effect of sulfate-reducing bacteria (SRB) on the corrosion behavior of the coating and the as-cast Ni-Al bronze (NAB) was investigated using electrochemical measurements and surface characterization. The Thermo-Cala simulation results showed that the alloy syste...
Source: Bioelectrochemistry - December 31, 2023 Category: Biochemistry Authors: Jie Cheng Yuping Wu Jizhou Duan G ökhan Polat Sheng Hong Jiangbo Cheng Source Type: research
Electrochemistry detection of estrogenic effect: Regulation of de novo purine synthesis and catabolism by gibberellin and fulvestrant
In this study, the estrogenic effect induced by gibberellin with ERα-dependent manner was found by E-screen and western blot methods, and the electrochemical signals of MCF-7 cells regulated by gibberellin and fulvestrant were investigated. The results showed that the electrochemical signals of MCF-7 cells were increased by gibberellin, while reduced by fulvestrant significantly, and displayed an extremely sensitive response to the effects of estrogenic effect induced by ERα agonist and antagonist. Western blot results showed that the expressions of phosphoribosyl pyrophosphate amidotransferase and hypoxanthine nucleotid...
Source: Bioelectrochemistry - December 31, 2023 Category: Biochemistry Authors: Yuhang Wang Shuo Zhao Shuhong Wang Jing Zhang Yanli Zhao Cai Ye Zhiyu Zhao Jinlian Li Hongkuan Shen Dongmei Wu Source Type: research
The influence of SRB on corrosion behavior of Cu-based medium-entropy alloy coating sprayed by HVOF
In this study, a novel Cu-based (Cu55Al20Ni12Ti8Si5, at.%) medium-entropy alloy (MEA) coating was prepared by high-velocity oxygen-fuel (HVOF) spraying technology. Thermo-Calc was employed to simulate the phase diagram of the alloy system. Phase composition and microstructure of the as-sprayed coating were characterized by means of XRD, FESEM, TEM and STEM/EDX. The effect of sulfate-reducing bacteria (SRB) on the corrosion behavior of the coating and the as-cast Ni-Al bronze (NAB) was investigated using electrochemical measurements and surface characterization. The Thermo-Cala simulation results showed that the alloy syste...
Source: Bioelectrochemistry - December 31, 2023 Category: Biochemistry Authors: Jie Cheng Yuping Wu Jizhou Duan G ökhan Polat Sheng Hong Jiangbo Cheng Source Type: research
Therapeutic perspectives of high pulse repetition rate electroporation
Bioelectrochemistry. 2023 Dec 21;156:108629. doi: 10.1016/j.bioelechem.2023.108629. Online ahead of print.ABSTRACTElectroporation, a technique that uses electrical pulses to temporarily or permanently destabilize cell membranes, is increasingly used in cancer treatment, gene therapy, and cardiac tissue ablation. Although the technique is efficient, patients report discomfort and pain. Current strategies that aim to minimize pain and muscle contraction rely on the use of pharmacological agents. Nevertheless, technical improvements might be a valuable tool to minimize adverse events, which occur during the application of sta...
Source: Bioelectrochemistry - December 30, 2023 Category: Biochemistry Authors: Alexia de Caro Franck Talmont Marie-Pierre Rols Muriel Golzio Jelena Kolosnjaj-Tabi Source Type: research
Novel electrochemical sensing strategy for ultrasensitive detection of tetracycline based on porphyrin/metal phthalocyanine-covalent organic framework
Bioelectrochemistry. 2023 Dec 24;156:108630. doi: 10.1016/j.bioelechem.2023.108630. Online ahead of print.ABSTRACTIn this work, a novel two-dimensional semiconducting metal covalent organic framework (CuTAPc-TFPP-COF) was synthesized and used as biosensing platform to construct aptasensor for trace detection of tetracycline (TC). The CuTAPc-TFPP-COF integrates the highly conjugated structure, large specific surface area, high porosity, abundant nitrogen functional groups, excellent electrochemical activity, and strong bioaffinity for aptamers, providing abundant active sites to effectively anchor aptamer strands. As a resu...
Source: Bioelectrochemistry - December 26, 2023 Category: Biochemistry Authors: Yingpan Song Yubo Meng Kun Chen Gailing Huang Sizhuan Li Lijun Hu Source Type: research
Novel electrochemical sensing strategy for ultrasensitive detection of tetracycline based on porphyrin/metal phthalocyanine-covalent organic framework
Bioelectrochemistry. 2023 Dec 24;156:108630. doi: 10.1016/j.bioelechem.2023.108630. Online ahead of print.ABSTRACTIn this work, a novel two-dimensional semiconducting metal covalent organic framework (CuTAPc-TFPP-COF) was synthesized and used as biosensing platform to construct aptasensor for trace detection of tetracycline (TC). The CuTAPc-TFPP-COF integrates the highly conjugated structure, large specific surface area, high porosity, abundant nitrogen functional groups, excellent electrochemical activity, and strong bioaffinity for aptamers, providing abundant active sites to effectively anchor aptamer strands. As a resu...
Source: Bioelectrochemistry - December 26, 2023 Category: Biochemistry Authors: Yingpan Song Yubo Meng Kun Chen Gailing Huang Sizhuan Li Lijun Hu Source Type: research
Novel electrochemical sensing strategy for ultrasensitive detection of tetracycline based on porphyrin/metal phthalocyanine-covalent organic framework
Bioelectrochemistry. 2023 Dec 24;156:108630. doi: 10.1016/j.bioelechem.2023.108630. Online ahead of print.ABSTRACTIn this work, a novel two-dimensional semiconducting metal covalent organic framework (CuTAPc-TFPP-COF) was synthesized and used as biosensing platform to construct aptasensor for trace detection of tetracycline (TC). The CuTAPc-TFPP-COF integrates the highly conjugated structure, large specific surface area, high porosity, abundant nitrogen functional groups, excellent electrochemical activity, and strong bioaffinity for aptamers, providing abundant active sites to effectively anchor aptamer strands. As a resu...
Source: Bioelectrochemistry - December 26, 2023 Category: Biochemistry Authors: Yingpan Song Yubo Meng Kun Chen Gailing Huang Sizhuan Li Lijun Hu Source Type: research
Novel electrochemical sensing strategy for ultrasensitive detection of tetracycline based on porphyrin/metal phthalocyanine-covalent organic framework
Bioelectrochemistry. 2023 Dec 24;156:108630. doi: 10.1016/j.bioelechem.2023.108630. Online ahead of print.ABSTRACTIn this work, a novel two-dimensional semiconducting metal covalent organic framework (CuTAPc-TFPP-COF) was synthesized and used as biosensing platform to construct aptasensor for trace detection of tetracycline (TC). The CuTAPc-TFPP-COF integrates the highly conjugated structure, large specific surface area, high porosity, abundant nitrogen functional groups, excellent electrochemical activity, and strong bioaffinity for aptamers, providing abundant active sites to effectively anchor aptamer strands. As a resu...
Source: Bioelectrochemistry - December 26, 2023 Category: Biochemistry Authors: Yingpan Song Yubo Meng Kun Chen Gailing Huang Sizhuan Li Lijun Hu Source Type: research
Novel electrochemical sensing strategy for ultrasensitive detection of tetracycline based on porphyrin/metal phthalocyanine-covalent organic framework
Bioelectrochemistry. 2023 Dec 24;156:108630. doi: 10.1016/j.bioelechem.2023.108630. Online ahead of print.ABSTRACTIn this work, a novel two-dimensional semiconducting metal covalent organic framework (CuTAPc-TFPP-COF) was synthesized and used as biosensing platform to construct aptasensor for trace detection of tetracycline (TC). The CuTAPc-TFPP-COF integrates the highly conjugated structure, large specific surface area, high porosity, abundant nitrogen functional groups, excellent electrochemical activity, and strong bioaffinity for aptamers, providing abundant active sites to effectively anchor aptamer strands. As a resu...
Source: Bioelectrochemistry - December 26, 2023 Category: Biochemistry Authors: Yingpan Song Yubo Meng Kun Chen Gailing Huang Sizhuan Li Lijun Hu Source Type: research
Electrochemical biosensor based on PAMAM functionalized MXene nanoplatform for detection of folate receptor
In this study, we in-situ synthesized a nanocomposite material with excellent conductivity and stability by grafting first-generation poly(amidoamine) dendrimers onto the MXene (Ti3C2TX) as the immobilized matrix (PAMAM@MXene). An electrochemical sensor was developed for FR monitor by loading the PAMAM@MXene on screen-printed carbon electrodes (SPCEs). Scanning electron microscopy (SEM) supported the effective synthesis of PAMAM@MXene. Under optimal conditions, the prepared sensor achieved the quantification of FR with a wide range of concentrations from 10 ng/mL to 1000 ng/mL with a detection limit (LOD) of 5.6 ng/mL. It ...
Source: Bioelectrochemistry - December 24, 2023 Category: Biochemistry Authors: Jiayi Jiang Linghuan Luo Na Ying Shu Wu Jun Ji Haoyuan Su Xiaoou Li Dongdong Zeng Source Type: research
Electrochemical biosensor based on PAMAM functionalized MXene nanoplatform for detection of folate receptor
In this study, we in-situ synthesized a nanocomposite material with excellent conductivity and stability by grafting first-generation poly(amidoamine) dendrimers onto the MXene (Ti3C2TX) as the immobilized matrix (PAMAM@MXene). An electrochemical sensor was developed for FR monitor by loading the PAMAM@MXene on screen-printed carbon electrodes (SPCEs). Scanning electron microscopy (SEM) supported the effective synthesis of PAMAM@MXene. Under optimal conditions, the prepared sensor achieved the quantification of FR with a wide range of concentrations from 10 ng/mL to 1000 ng/mL with a detection limit (LOD) of 5.6 ng/mL. It ...
Source: Bioelectrochemistry - December 24, 2023 Category: Biochemistry Authors: Jiayi Jiang Linghuan Luo Na Ying Shu Wu Jun Ji Haoyuan Su Xiaoou Li Dongdong Zeng Source Type: research
Electrochemical biosensor based on PAMAM functionalized MXene nanoplatform for detection of folate receptor
In this study, we in-situ synthesized a nanocomposite material with excellent conductivity and stability by grafting first-generation poly(amidoamine) dendrimers onto the MXene (Ti3C2TX) as the immobilized matrix (PAMAM@MXene). An electrochemical sensor was developed for FR monitor by loading the PAMAM@MXene on screen-printed carbon electrodes (SPCEs). Scanning electron microscopy (SEM) supported the effective synthesis of PAMAM@MXene. Under optimal conditions, the prepared sensor achieved the quantification of FR with a wide range of concentrations from 10 ng/mL to 1000 ng/mL with a detection limit (LOD) of 5.6 ng/mL. It ...
Source: Bioelectrochemistry - December 24, 2023 Category: Biochemistry Authors: Jiayi Jiang Linghuan Luo Na Ying Shu Wu Jun Ji Haoyuan Su Xiaoou Li Dongdong Zeng Source Type: research
Smartphone-assisted paper-based electrochemical immunosensor for SARS-CoV-2 detection in saliva
Bioelectrochemistry. 2023 Nov 29;156:108619. doi: 10.1016/j.bioelechem.2023.108619. Online ahead of print.ABSTRACTHerein, we developed a new waste solution-free paper-based electrochemical immunosensor for SARS-CoV-2 detection in saliva, by combining vertical and lateral flow. In detail, the device was constituted of a reservoir containing all reagents for the construction of the immunological chain onto the magnetic beads and a lateral flow holder which contained a polyester-based electrode, a magnet, and an adsorbent pad. The measurement was carried out by adding the saliva sample into the reservoir, followed by the addi...
Source: Bioelectrochemistry - December 21, 2023 Category: Biochemistry Authors: Laura Fabiani Luca Fiore Silvia Fillo Nino D'Amore Riccardo De Santis Florigio Lista Fabiana Arduini Source Type: research
A signal amplification electrochemiluminescence biosensor based on Ru(bpy) < sub > 3 < /sub > < sup > 2+ < /sup > and β-cyclodextrin for detection of AFP
Bioelectrochemistry. 2023 Dec 14;156:108626. doi: 10.1016/j.bioelechem.2023.108626. Online ahead of print.ABSTRACTBy combining two different materials, metal-organic frameworks (MOF) and β-cyclodextrins (β-CD), a signal amplification electrochemical luminescence (ECL) immunosensor was constructed to realize the sensitive detection of AFP. The indium-based metal-organic framework (In-MOF) was used as the carrier of Ru(bpy)32+, and Ru(bpy)32+ was immobilized by In-MOF through suitable pore size and electrostatic interaction. At the same time, using host-guest recognition, β-CD enriched TPA into the hydrophobic cavity for ...
Source: Bioelectrochemistry - December 21, 2023 Category: Biochemistry Authors: Bing Cong Wenjin Liang Wenjing Lai Mingzhe Jiang Chaoyun Ma Chulei Zhao Wenwen Jiang Shaopeng Zhang Hongling Li Chenglin Hong Source Type: research
