The onset of < em > de novo < /em > autoantibodies in healthcare workers after mRNA based anti-SARS-CoV-2 vaccines: a single centre prospective follow-up study
Autoimmunity. 2023 Dec;56(1):2229072. doi: 10.1080/08916934.2023.2229072.ABSTRACTNowadays, data concerning the risk of autoimmune disease after SARS-CoV-2 (COVID-19) vaccination is controversial. The aim of this single centre prospective follow-up study was to evaluate whether healthcare workers (HCWs) vaccinated with BNT162b2 mRNA and mRNA-1273 will show a development and/or a persistence of autoantibodies, focussing on the detection of antibodies against nuclear antigens (antinuclear antibodies, ANA). We enrolled 155 HCWs, however only 108 of them received the third dose and were considered for further analysis. Blood sa...
Source: Autoimmunity - June 29, 2023 Category: Allergy & Immunology Authors: M C Sacchi C Pelazza M Bertolotti L Agatea P De Gaspari S Tamiazzo D Ielo P Stobbione M Grappiolo T Bolgeo P Novel M M Ciriello A Maconi Source Type: research