Early Surgery for Infective Endocarditis Complicated with Neurological Injury
Infective endocarditis (IE) has an incidence of approximately 3 to 10 per 100  000 person-years.(1) Its global morbidity and mortality rates remain high despite improvements in the guidelines for treatment and surgical interventions.(1) Embolic neurological events occur in 20% to 40% of active IE cases; these have been suggested to increase mortality during short-term and l ong-term follow-up.(2-5) For patients presenting with neurological complications on admission or with such complications before operation, determining the optimal timing for cardiac surgery following stroke is challenging.(6) One small randomized cont...
Source: Journal of Cardiothoracic and Vascular Anesthesia - February 14, 2024 Category: Anesthesiology Authors: Sing-Siou Tsai, Victor Chien-Chia Wu, Yi-Hsin Chan, Dong-Yi Chen, Yu-Ting Cheng, Kuo-Chun Hung, Fu-Chih Hsiao, Ying-Chang Tung, Chia-Pin Lin, Pao-Hsien Chu, Yen Chu, Shao-Wei Chen Tags: Original Article Source Type: research

Single-Chamber and Dual-Chamber Pacemaker Devices in Adults with Moderate and Complex Congenital Heart Disease: A Single Tertiary Referral Center Experience
AbstractThe number of device implantation procedures has increased in adult patients with congenital heart disease (ACHD). Despite significant improvements in materials and implantation techniques, these patients are exposed to higher risk of device related complications than general population. Herein, we describe our single tertiary referral center experience on transvenous pacemaker (PM) implantation and follow-up in adult patients with moderate and complex congenital heart disease (CHD) as limited data are available on long-term outcome. We considered all adults with moderate and complex CHD aged more than 16 years who...
Source: Pediatric Cardiology - February 14, 2024 Category: Cardiology Source Type: research

Single-Chamber and Dual-Chamber Pacemaker Devices in Adults with Moderate and Complex Congenital Heart Disease: A Single Tertiary Referral Center Experience
AbstractThe number of device implantation procedures has increased in adult patients with congenital heart disease (ACHD). Despite significant improvements in materials and implantation techniques, these patients are exposed to higher risk of device related complications than general population. Herein, we describe our single tertiary referral center experience on transvenous pacemaker (PM) implantation and follow-up in adult patients with moderate and complex congenital heart disease (CHD) as limited data are available on long-term outcome. We considered all adults with moderate and complex CHD aged more than 16 years who...
Source: Mammalian Genome - February 14, 2024 Category: Genetics & Stem Cells Source Type: research

Early Surgery for Infective Endocarditis Complicated With Neurologic Injury
To estimate the association between early surgery and the risk of mortality in patients with left-sided infective endocarditis in the context of stroke. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - February 14, 2024 Category: Anesthesiology Authors: Sing-Siou Tsai, Victor Chien-Chia Wu, Yi-Hsin Chan, Dong-Yi Chen, Yu-Ting Cheng, Kuo-Chun Hung, Fu-Chih Hsiao, Ying-Chang Tung, Chia-Pin Lin, Pao-Hsien Chu, Yen Chu, Shao-Wei Chen Tags: Original Article Source Type: research

Sensitizing methicillin-resistant < em > Staphylococcus aureus < /em > (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine
Antimicrob Agents Chemother. 2024 Feb 13:e0162723. doi: 10.1128/aac.01627-23. Online ahead of print.ABSTRACTMethicillin-resistant Staphylococcus aureus (MRSA) strains are a major challenge for clinicians due, in part, to their resistance to most β-lactams, the first-line treatment for methicillin-susceptible S. aureus. A phenotype termed "NaHCO3-responsiveness" has been identified, wherein many clinical MRSA isolates are rendered susceptible to standard-of-care β-lactams in the presence of physiologically relevant concentrations of NaHCO3, in vitro and ex vivo; moreover, such "NaHCO3-responsive" isolates can be effective...
Source: Antimicrobial Agents and Chemotherapy - February 13, 2024 Category: Microbiology Authors: Selvi C Ersoy Richard A Proctor Warren E Rose Wessam Abdelhady Sook-Ha Fan Sabrina L Madrigal Ahmed M Elsayed Henry F Chambers Rita G Sobral Arnold S Bayer Source Type: research

C-terminal deletion of RelA protein is suggested as a possible cause of infective endocarditis recurrence with < em > Enterococcus faecium < /em >
Antimicrob Agents Chemother. 2024 Feb 13:e0108323. doi: 10.1128/aac.01083-23. Online ahead of print.ABSTRACTInfective endocarditis (IE) caused by Enterococcus spp. represents the third most common cause of IE, with high rates of relapse compared with other bacteria. Interestingly, late relapses (>6 months) have only been described in Enterococcus faecalis, but here we describe the first reported IE relapse with Enterococcus faecium more than a year (17 months) after the initial endocarditis episode. Firstly, by multi locus sequence typing (MLST), we demonstrated that both isolates (EF646 and EF641) belong to the same se...
Source: Antimicrobial Agents and Chemotherapy - February 13, 2024 Category: Microbiology Authors: Jos é Manuel Ortiz de la Rosa Guillermo Mart ín-Gutiérrez Carlos S Casimiro-Soriguer Mar ía Adelina Gimeno-Gascón Jos é Miguel Cisneros Ar ístides de Alarcón Jos é Antonio Lepe Source Type: research

New Insights into Mortality-Related Risk Factors in Infective Endocarditis: Results from the Brandenburg State Endocarditis Register
Conclusion Our first registry data show the complexity of endocarditis patients and the challenging treatment. Some risk factors can be treated preoperatively. For instance, hypalbuminemia and the duration of the procedure can be controlled with adequate albumin substitution and carefully planned procedures restricted to the essential requirements, that is, hybrid approaches with consecutive interventions. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - February 9, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Ostovar, Roya Schroeter, Filip Seifi Zinab, Frarzane Fritzsche, Dirk Minden, Hans-Heinrich Lasheen, Nirmeen Hartrumpf, Martin Ritter, Oliver D örr, Gesine Albes, Johannes Maximilian Tags: Original Cardiovascular Source Type: research

Papillary fibroelastoma originating from the atrial septum touching the mitral valve leading to infective endocarditis: a case report
Cardiac papillary fibroelastoma is a rare benign tumor, which is often mistaken for a vegetation. Predominantly asymptomatic, it can cause life-threatening complications. Although rare, mobile papillary fibroe... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - February 9, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Koji Funaishi, Hirofumi Kasahara, Naohiko Oki, Tomoyori Nakatogawa and Kazuhiro Yamanoi Tags: Case Report Source Type: research

Healthcare exposures and associated risk of endocarditis after open-heart cardiac valve surgery
This study aimed to i... (Source: BMC Medicine)
Source: BMC Medicine - February 8, 2024 Category: Internal Medicine Authors: Timothy N. Kwan, David Brieger, Vincent Chow, Arnold Chin Tse Ng, Gemma Kwan, Karice Hyun, Raymond Sy, Leonard Kritharides and Austin Chin Chwan Ng Tags: Research article Source Type: research

Multiple pulmonary aneurysms and infective endocarditis as initial presentation of persistent ductus arteriosus
Arch Cardiol Mex. 2024 Feb 2. doi: 10.24875/ACM.23000058. Online ahead of print.NO ABSTRACTPMID:38306411 | DOI:10.24875/ACM.23000058 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - February 2, 2024 Category: Cardiology Authors: David J S ánchez-Amaya Mateo D Guti érrez-Castañeda Diego Araiza-Garaygordobil Alexandra Arias-Mendoza Source Type: research

Infective Endocarditis Is the Leading Cause of Infection-Associated Cutaneous Vasculitis - A Single Academic Center Dermatology Consultant Experience
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 2, 2024 Category: Dermatology Authors: Jordan Phillipps, Carine Lama, John Strickley, Amy Musiek Source Type: research

Critically ill patients with infective endocarditis, neurological complications and indication for cardiac surgery: a multicenter propensity-adjusted study
The benefit –risk balance and optimal timing of surgery for severe infective endocarditis (IE) with ischemic or hemorrhagic strokes is unknown. The study aim was to compare the neurological outcome between pati... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 2, 2024 Category: Intensive Care Authors: Alexandre Gros, Benjamin Seguy, Guillaume Bonnet, Yves-Olivier Guettard, Xavier Pillois, Renaud Prevel, Arthur Orieux, Julien Ternacle, Sebastien Pr éau, Yoan Lavie-Badie, Elisabeth Coupez, Rémi Coudroy, Delphine Marest, Raphaël P. Martins, Didier Grus Tags: Research Source Type: research

Infective endocarditis is the leading cause of infection-associated cutaneous vasculitis: A single academic center dermatology consultant experience
To the Editor: Cutaneous vasculitis (CV) has diverse manifestations and etiologies —infectious etiologies are common in children whereas idiopathic or underlying systemic conditions are common in adults.1 Infective endocarditis (IE) can cause CV, however, the lack of pathognomonic cutaneous findings makes this diagnosis challenging.2 Importantly, competing etiologies complicate management, as empiric treatments (eg, immunosuppression for infectious etiologies) can be fatal. To investigate the observation that many patients with CV had IE, we conducted a single-institution retrospective study from 2018 to 2023 to characte...
Source: Journal of the American Academy of Dermatology - February 2, 2024 Category: Dermatology Authors: Jordan Phillipps, Carine Lama, John Strickley, Amy Musiek Tags: Research letter Source Type: research

Staphylococcus succinus Infective Endocarditis, France
L. d ’Epenoux et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 1, 2024 Category: Infectious Diseases Source Type: research

Infective Endocarditis: The role of PET imaging in diagnosis and management
Positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG) has recently emerged as an increasingly used alternative and supplementary imaging modality for the diagnosis of infective endocarditis. 18F-FDG PET/CT imaging for IE is given a Class I recommendation (level of evidence B) and is therefore recommended in cases of possible prosthetic valve IE to both detect valvular lesions, as well as confirm the diagnosis of IE. They have also given a class I recommendation (level of evidence B) for brain and whole-body 18F-FDG PET/CT and/or MRI imaging to detect peripheral lesions for patients with either native or ...
Source: Journal of Medical Imaging and Radiation Sciences - February 1, 2024 Category: Radiology Authors: Kevin Emery Boczar, Lawrence Lau, Nuha Hejji, Christiane Wiefels Tags: Short Communication Source Type: research