Haemophilus influenzae endocarditis: a case report and literature review
ConclusionNative tricuspid valve IE is an uncommon entity, especially in the absence of IV drug use. Haemophilus influenzae is an extremely rare cause of IE, with a literature review showing merely 15 reported cases. This article cites the 16th case of HI-IE published in the literature. (Source: Infection)
Source: Infection - March 15, 2024 Category: Infectious Diseases Source Type: research

Aspirin Responsiveness in a Cohort of Pediatric Patients with Right Ventricle to Pulmonary Artery Conduits and Transcatheter Valve Replacement Systems
AbstractThe aim of this study was to determine the rate of aspirin responsiveness in a cohort of pediatric patients with in situ xenograft valved right ventricle to pulmonary artery (RV-PA) conduits and/or transcatheter valve replacements (TVR). Aspirin is routinely prescribed to these patients. Optimizing anti-platelet therapy could promote valve longevity and reduce the risk of infective endocarditis in this at-risk group. This was a prospective, observational study. Patients were recruited from both ward and outpatient settings. Patients were eligible if under 18 years and taking aspirin. Non-response to aspirin was def...
Source: Mammalian Genome - March 15, 2024 Category: Genetics & Stem Cells Source Type: research

Hybrid approach to management for a patient with culture negative infective endocarditis with profunda femoris mycotic pseudoaneurysm: A case report and review of the literature
We present a case of a patient who underwent mitral valve repair for severe mitral regurgitation secondary to culture negative IE which was complicated by multiple mycotic pseudoaneurysm. The PFA pseudoaneurysm which was affected and was complicated with a large hematoma compressing the femoral nerve. This was managed by a staged hybrid approach. Endovascular stenting was performed first to seal the pseudoaneurysm and facilitate open surgical repair using a reversed interposition saphenous vein graft. To the best of our knowledge, this is the first reported case of a PFA mycotic aneurysm (MA) being managed by a hybrid appr...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Fahad M. Alshair, Abdullah H. Baghaffar, Mazin A. Fatani, Reda A. jamjoom Tags: CASE REPORT Source Type: research

Outpatient parenteral antimicrobial therapy (OPAT) in Germany: insights and clinical outcomes from the K-APAT cohort study
ConclusionThe study demonstrates that OPAT can be safely conducted in Germany. In preparation for its broader implementation, crucial next steps include creating medical guidelines, fostering interdisciplinary and inter-sectoral communication, as well as creating financial and structural regulations that facilitate and encourage the adoption of OPAT.Trial registration numberNCT04002453. (Source: Infection)
Source: Infection - March 13, 2024 Category: Infectious Diseases Source Type: research

18F-FDG PET/CT and radiolabeled leukocyte SPECT/CT imaging for the evaluation of cardiovascular infection in the multimodality context
This document on cardiovascular infection, including infective endocarditis, is the first in the American Society of Nuclear Cardiology Imaging Indications (ASNC I2)  series to assess the role of radionuclide imaging in the multimodality context for the evaluation of complex systemic diseases with multi-societal involvement including pertinent disciplines. A rigorous modified Delphi approach was used to determine consensus clinical indications, diagnostic crite ria, and an algorithmic approach to diagnosis of cardiovascular infection including infective endocarditis. (Source: Heart Rhythm)
Source: Heart Rhythm - March 11, 2024 Category: Cardiology Authors: Jamieson M. Bourque, Ulrika Birgersdotter-Green, Paco E. Bravo, Ricardo P.J. Budde, Wengen Chen, Vivian H. Chu, Vasken Dilsizian, Paola Anna Erba, Cesia Gallegos Kattan, Gilbert Habib, Fabien Hyafil, Yiu Ming Khor, Jaimie Manlucu, Pamela Kay Mason, Edward Tags: Consensus Statement Source Type: research

Impact of infective versus sterile transvenous lead removal on 30-day outcomes in cardiac implantable electronic devices
ConclusionHigher in-hospital mortality and rates of thromboembolic events associated with TLR resulting from infective indications may warrant further pursuing this diagnosis in patients. (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - March 9, 2024 Category: Cardiology Source Type: research

Clinical and microbiological profile of Viridans group streptococcal bacteraemia; experience from South India
CONCLUSIONS: VGS are an important cause of bacteraemia and was associated with 19% mortality in our study. High rates of penicillin and ceftriaxone resistance are a reason of concern. Molecular diagnostics like matrix assisted laser desorption ionization-time of flight (MALDI-TOF) identification must be increasingly applied for species identification considering that a substantial number of isolates were not identified to species level.PMID:38456022 | PMC:PMC10917554 | DOI:10.53854/liim-3201-5 (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - March 8, 2024 Category: Infectious Diseases Authors: Rajalakshmi Arjun Vettakkara Kandy Muhammed Niyas Febeena Hussain Sandeep Surendran Viji Mohan Source Type: research