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Talaromyces marneffei endocarditis initially detected by Next Generation Sequencing: A case report
CONCLUSION: Infective endocarditis is becoming more and more common in the elderly due to the widely use of invasive surgical procedures and implantation of intracardiac devices. The diagnosis and treatment of T. marneffei endocarditis is challenging because of its rarity. Here, we discussed a case of T. marneffei endocarditis, and emphasized the role of mNGS in early diagnosis, which is of great significance for treatment and survival rate of patients.PMID:38394877 | DOI:10.1016/j.ijmm.2024.151615 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - February 23, 2024 Category: Microbiology Authors: Youqi Ji Bingqian Zhuo Tao Jiang Mengyuan Chen Wei Xu Yuhuan Shen Dongqing Cheng Yumei Ge Source Type: research

Case reports involving coinfection with Avibacterium paragallinarum and Ornithobacterium rhinotracheale in broiler chickens and Avibacterium endocarditis in broiler breeding hens in Poland
Avian Pathol. 2024 Feb 22:1-33. doi: 10.1080/03079457.2024.2323029. Online ahead of print.ABSTRACTAbstractThe study describes three clinical cases of infection with Avibacterium spp.. In case no. 1, respiratory clinical signs and high mortality (0.7-4.2% daily; total 21.2%) in broiler chickens Ross 308 were shown to be caused by coinfection with sequence type 9 of O. rhinotracheale presumptive serotype A and A. paragallinarum presumptive serotype B. The identical PFGE restriction pattern (pulsotype) of seven A. paragallinarum isolates indicated that infectious coryza (IC) in broilers was caused by the same clone. In cases ...
Source: Avian Pathology - February 22, 2024 Category: Pathology Authors: Dagmara St ępień-Pyśniak Marta Dec Tomasz Hauschild Olimpia Kursa Agnieszka Marek Jaros ław Wilczyński Micha ł Brzeski Source Type: research

Oral streptococci: modulators of health and disease
Streptococci are primary colonizers of the oral cavity where they are ubiquitously present and an integral part of the commensal oral biofilm microflora. The role oral streptococci play in the interaction with the host is ambivalent. On the one hand, they function as gatekeepers of homeostasis and are a prerequisite for the maintenance of oral health - they shape the oral microbiota, modulate the immune system to enable bacterial survival, and antagonize pathogenic species. On the other hand, also recognized pathogens, such as oral Streptococcus mutans and Streptococcus sobrinus, which trigger the onset of dental caries be...
Source: Frontiers in cellular and infection microbiology - February 22, 2024 Category: Microbiology Source Type: research

Getting to the heart of the matter - Are two agents really better than one for the treatment of staphylococcal infective endocarditis?
The recently published 2023 update from the European Society of Cardiology (ESC) regarding the management of infective endocarditis introduces many welcome changes. Commendable are the transition towards outpatient care and the adoption of oral therapeutic regimens for carefully selected and clinically stable patients [1]. However, the management of these patients still presents numerous challenges, particularly in the context of selecting the most appropriate antimicrobial regimen. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - February 21, 2024 Category: Infectious Diseases Authors: James Donnelly, Helene McDermott, Sadhbh Gash, Ciara O'Connor, Karina O'Connell, Sinead O'Donnell, Binu Dinesh, Karen Burns, Fidelma Fitzpatrick Tags: Perspective Source Type: research

Getting to the heart of the matter —are two agents really better than one for the treatment of staphylococcal infective endocarditis?
The recently published 2023 update from the European Society of Cardiology (ESC) regarding the management of infective endocarditis introduces many welcome changes. Commendable is the transition toward outpatient care and the adoption of oral therapeutic regimens for carefully selected and clinically stable patients [1]. However, the management of these patients still presents numerous challenges, particularly in the context of selecting the most appropriate antimicrobial regimen. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - February 21, 2024 Category: Infectious Diseases Authors: James Donnelly, Helene McDermott, Sadhbh Gash, Ciara O'Connor, Karina O'Connell, Sinead O'Donnell, Binu Dinesh, Karen Burns, Fidelma Fitzpatrick Tags: Perspective Source Type: research