Hypertrophic Cardiomyopathy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Current perspectives of sudden cardiac death management in hypertrophic cardiomyopathy
In this study, we review the latest findings regarding pathogenesis, risk stratification, and prevention of SCD in HCM patients, highlighting the clinic practice of cardiovascular magnetic resonance imaging for SCD management. (Source: Heart Failure Reviews)
Source: Heart Failure Reviews - March 1, 2024 Category: Cardiology Source Type: research

Hypertrophic cardiomyopathy: New pathogenic variant in MYH7
Med Clin (Barc). 2024 Feb 28:S0025-7753(24)00062-9. doi: 10.1016/j.medcli.2023.12.020. Online ahead of print.NO ABSTRACTPMID:38423942 | DOI:10.1016/j.medcli.2023.12.020 (Source: Medicina Clinica)
Source: Medicina Clinica - February 29, 2024 Category: General Medicine Authors: Fernando Vargas-Urs úa Mar ía Melendo-Viu Andr és Íñiguez-Romo Source Type: research

Is There a Role for Alcohol Septal Ablation in Young Patients with Medically Refractory Hypertrophic Obstructive Cardiomyopathy?
AbstractSurgical myectomy is recommended for symptomatic hypertrophic obstructive cardiomyopathy (HOCM) after optimal pharmacological therapy. Percutaneous transluminal septal myocardial ablation (PTSMA) is reserved for high-risk adults. Symptomatic patients below 25 years underwent either surgery or PTSMA after heart-team discussion and informed consent. Echocardiography assessed gradients in surgical group. PTSMA group underwent invasive transseptal hemodynamic assessment, selective coronary angiography and super-selective cannulation of septal perforators u sing microcatheters. Contrast echocardiography through the mi...
Source: Pediatric Cardiology - February 28, 2024 Category: Cardiology Source Type: research

Generation of induced pluripotent stem cell lines from two unrelated individuals with familial hypertrophic cardiomyopathy carrying MYBPC3 nonsense mutations
Stem Cell Res. 2024 Feb 24;76:103362. doi: 10.1016/j.scr.2024.103362. Online ahead of print.ABSTRACTFamilial hypertrophic cardiomyopathy (HCM) stands as a predominant heart condition, characterised by left ventricle hypertrophy in the absence of any associated loading conditions, with affected individuals having an increased risk of developing heart failure and sudden cardiac death (SCD). Two induced pluripotent stem cell (iPSC) lines were derived from peripheral blood mononuclear cells obtained from two unrelated individuals with previously reported nonsense mutations in the MYBPC3 gene. The first individual is a 48-year-...
Source: Cell Research - February 28, 2024 Category: Cytology Authors: Marta Ribeiro Joanna Jager Marta Furtado Teresa Carvalho Joaquim M S Cabral Dulce Brito Maria Carmo-Fonseca Sandra Martins Sim ão Teixeira da Rocha Source Type: research

Mitral regurgitation mechanisms related to systolic anterior motion in hypertrophic cardiomyopathy
CONCLUSIONS: Our preliminary data suggested that chordal cutting with septal myectomy was associated with an improvement in the tenting area, contributing to MR severity. This procedure may serve as an effective therapy for patients with SAM and significant MR.PMID:38410607 | PMC:PMC10894419 | DOI:10.21037/jtd-23-1206 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 27, 2024 Category: Respiratory Medicine Authors: Hideyuki Hayashi Sameer K Singh Rebecca T Hahn Keitaro Akita Paul Kurlansky Jocelyn Sun Vijay Vedula Jay S Leb Yuichi J Shimada Shepard D Weiner Hiroo Takayama Source Type: research