Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

A Rare Ectopic Parathyroid Adenoma in the Prevertebral Space
We present a case of a patient admitted to the hospital with severe hypercalcemia and elevated parathyroid hormone levels, in whom imaging revealed two distinct parathyroid masses in the prevertebral space, representing a rare and atypical location for parathyroid tissue. This case highlights the importance of considering ectopic parathyroid adenomas as a potential cause of hyperparathyroidism and discusses the diagnostic challenges and management strategies associated with such cases.PMID:38520268 | DOI:10.1177/00031348241241688 (Source: The American Surgeon)
Source: The American Surgeon - March 23, 2024 Category: Surgery Authors: Alex Tran Manual Molina-Vega Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Reference values of parathyroid hormone in very low birth weight infants
CONCLUSIONS: The physiological range for PTH levels for preterm neonates without 25(OH)D deficiency was estimated as 0.9 - 11.9 pmol/l (8.5 - 112.3 pg/ml). It seems that elevation of serum PTH above this range can be considered as hyperparathyroidism in very low birth weight infant.PMID:38520177 | DOI:10.1177/00045632241245942 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - March 23, 2024 Category: Biochemistry Authors: Tomas Matejek Bara Zapletalova Jaroslav Stranik Lenka Zaloudkova Vladimir Palicka Source Type: research

Complex Primary Hyperparathyroidism
Primary hyperparathyroidism can be sporadic or part of a genetic syndrome, such as MEN1 or HPT-JT. Diagnosis of hereditary HPT requires a thorough history and physical. Parathyroidectomy is curative with greater than 95% success. However, some patients have persistent or recurrent disease requiring reoperation. Reoperative parathyroidectomy is technically challenging, and localizing the pathologic gland can difficult. Patients needing reoperation should undergo evaluation by a high-volume surgeon. Care should be taken to obtain all of the preoperative workup and operative note from the initial surgery. Radioguided parathyr...
Source: Surgical Clinics of North America - March 23, 2024 Category: Surgery Authors: Sanjana Balachandra, Jessica Fazendin, Herbert Chen Source Type: research

Genetic profile of a large Spanish cohort with hypercalcemia
ConclusionsOur study demonstrates the importance of genetic analysis through massive sequencing to obtain a clinical diagnosis of certainty. The identification of patients with a genetic cause is important for the appropriate treatment and identification of family members at risk of the disease. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 22, 2024 Category: Endocrinology Source Type: research

Intraoperative radio-guided localization of parathyroid adenomas using 3D freehand SPECT technology
AbstractParathyroidectomy for primary hyperparathyroidism (PHPT) could have poor outcomes, even with accurate preoperative localization of the adenomas, because their intraoperative localization can be challenging. Freehand single photon emission computed tomography (fhSPECT) is a new technique for radio-guided intraoperative navigation. Its use during parathyroidectomy could be useful and such data are limited. We herein present our experience on the feasibility of fhSPECT for intraoperative detection of abnormal parathyroid glands. We retrospectively reviewed the clinical data of 55 patients (30 –77 years old) with PH...
Source: Updates in Surgery - March 22, 2024 Category: Surgery Source Type: research

Parathyroid thermal ablation in 2023: the advent of a third wave for primary hyperparathyroidism
(Source: European Radiology)
Source: European Radiology - March 21, 2024 Category: Radiology Source Type: research

Surgical Management of Secondary and Tertiary Hyperparathyroidism
Secondary hyperparathyroidism (SHPT) often arises from kidney disease and is characterized by elevated parathyroid hormone (PTH) levels. The reported optimal PTH level to balance the compensatory physiologic response in SHPT with the pathologic morbidity and mortality has changed over time with our evolving understanding. Parathyroidectomy for kidney-related hyperparathyroidism requires consideration of the patient ’s dialysis status, potential for kidney transplantation, and medical history. Extent of parathyroidectomy and intraoperative decision-making requires consideration to maximize cure with the risk of permanent ...
Source: Surgical Clinics of North America - March 21, 2024 Category: Surgery Authors: Marisa Bartz-Kurycki, Sophie Dream Source Type: research

Renal hyperparathyroidism- a risk factor in the development of encapsulating peritoneal sclerosis
ConclusionHigh levels of calcium and phosphate in patients on PD were identified to be risk factors for EPS development. Possible reasons for this may be an imbalance of pro-calcifying factors and calcification inhibitors promoting peritoneal calcification which increases peritoneal stiffness. Mechanical alterations may trigger, unregulated fibrosis and subsequent development of EPS. Improved management of secondary hyperparathyroidism during PD may ultimately diminish the EPS risk. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 19, 2024 Category: Endocrinology Source Type: research

Severe secondary hyperparathyroidism: an increasing problem in CKD but the best management option is still unknown
J Bras Nefrol. 2024 Apr-Jun;46(2):e2024E004. doi: 10.1590/2175-8239-JBN-2024-E004en.NO ABSTRACTPMID:38498844 | DOI:10.1590/2175-8239-JBN-2024-E004en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - March 18, 2024 Category: Urology & Nephrology Authors: Mark Kung Dah Tiong Nigel David Toussaint Source Type: research