Management Modalities of Aggressive Brown Tumor of the Jaws —a Case Series
We report a case series of four patients who presented with brown tumor of both maxilla and mandible. A complete assessment of the medical history, blood investigations and radiological findings combined with biopsy results is necessary for a correct diagnosis. The standard treatment of the Brown tumors is not a surgical resection, but the treatment of the cause of the tumor, which in this case is hyperparathyroidism. However in our case, the extent of the lesion and the non resolution after the parathyroidectomy necessitated a surgical approach in two of our patients however two responded well to medical management alone....
Source: Journal of Maxillofacial and Oral Surgery - April 8, 2024 Category: ENT & OMF Source Type: research
Molecules, Vol. 29, Pages 1636: Comparative Performance Assessment of Novel Fluorescence Immunoassay POCTs for Measuring Circulating Levels of Vitamin-D
onio D’Avolio
Vitamin D (Vit D) is a fat-soluble molecule acting like a hormone, and it is involved in several biological mechanisms such as gene expression, calcium homeostasis, bone metabolism, immune modulation, viral protection, and neuromuscular functions. Vit D deficiency can lead to chronic hypocalcemia, hyperparathyroidism, and many other pathological conditions; in this context, low and very low levels of 25-hydroxy-vitamin D (25-OH-D) were found to be associated with an increased risk of COVID-19 infection and the likelihood of many severe diseases. For all these reasons, it is important to quantify and mon...
Source: Molecules - April 5, 2024 Category: Chemistry Authors: Alice Palermiti Alessandra Manca Fabrizio Mastrantonio Domenico Maiese Aurora Curatolo Miriam Antonucci Marco Simiele Amedeo De Nicol ò Antonio D ’Avolio Tags: Communication Source Type: research
Correction to: "Trabecular Bone Score as a More Sensitive Tool to Evaluate Bone Involvement in MEN1-related Primary Hyperparathyroidism"
J Clin Endocrinol Metab. 2024 Apr 4:dgae186. doi: 10.1210/clinem/dgae186. Online ahead of print.NO ABSTRACTPMID:38573910 | DOI:10.1210/clinem/dgae186 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 4, 2024 Category: Endocrinology Source Type: research
Outcome of surgical parathyroidectomy for tertiary hyperparathyroidism in kidney transplant recipients: tertiary hyperparathyroidism should not be ignored, for the sake of precious allografts
Ren Fail. 2024 Dec;46(1):2333919. doi: 10.1080/0886022X.2024.2333919. Epub 2024 Apr 4.ABSTRACTTertiary hyperparathyroidism is a complication of kidney transplantation. This complicated condition carries over from the dialysis period and varies according to the function of the transplanted allograft. Treatments include pharmacotherapy (mainly using calcimimetics) and parathyroidectomy, but calcimimetics are currently not covered by the national insurance system in Japan. Two types of parathyroidectomy can be performed: subtotal parathyroidectomy; and total parathyroidectomy with partial autograft. Both types can be expected...
Source: Renal Failure - April 4, 2024 Category: Urology & Nephrology Authors: Michio Nakamura Shinya Takiguchi Saeko Uehara Yusuke Tomita Source Type: research
Outcome of surgical parathyroidectomy for tertiary hyperparathyroidism in kidney transplant recipients: tertiary hyperparathyroidism should not be ignored, for the sake of precious allografts
Ren Fail. 2024 Dec;46(1):2333919. doi: 10.1080/0886022X.2024.2333919. Epub 2024 Apr 4.ABSTRACTTertiary hyperparathyroidism is a complication of kidney transplantation. This complicated condition carries over from the dialysis period and varies according to the function of the transplanted allograft. Treatments include pharmacotherapy (mainly using calcimimetics) and parathyroidectomy, but calcimimetics are currently not covered by the national insurance system in Japan. Two types of parathyroidectomy can be performed: subtotal parathyroidectomy; and total parathyroidectomy with partial autograft. Both types can be expected...
Source: Renal Failure - April 4, 2024 Category: Urology & Nephrology Authors: Michio Nakamura Shinya Takiguchi Saeko Uehara Yusuke Tomita Source Type: research
Predictive analysis of severe hypocalcemia following total parathyroidectomy for renal secondary hyperparathyroidism
CONCLUSIONS: Younger patients with renal SHPT who have elevated preoperative iPTH and ALP levels are at an increased risk of experiencing severe hypocalcemia following TPTX. These findings underscore the importance of careful preoperative assessment and monitoring to mitigate the risk of this complication.PMID:38567585 | DOI:10.26355/eurrev_202403_35726 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: T Bi S-J Bai G-M Cheng X-D Feng W Zhang Source Type: research
Predictive analysis of severe hypocalcemia following total parathyroidectomy for renal secondary hyperparathyroidism
CONCLUSIONS: Younger patients with renal SHPT who have elevated preoperative iPTH and ALP levels are at an increased risk of experiencing severe hypocalcemia following TPTX. These findings underscore the importance of careful preoperative assessment and monitoring to mitigate the risk of this complication.PMID:38567585 | DOI:10.26355/eurrev_202403_35726 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: T Bi S-J Bai G-M Cheng X-D Feng W Zhang Source Type: research
