Correction for 'multicentre, open-label, randomised, controlled trial to compare early intervention with calcimimetics and conventional therapy in preventing coronary artery calcification in patients with secondary hyperparathyroidism (UPCOMING): a study protocol
This article has been corrected since it was published online. The authors wish to add a statement about the sharing of data for this trial, in line with BMJ Open’s policy on data sharing. The jRCT registry (the registry where information for this trial is listed) provides a section on data sharing, which is titled "Plan to share IPD" (individual participant data), and the authors had already filled out this section when initially registering the study. The jRCT system only makes this section publicly available after the study is complete. Data generated from our study and any other necessary materials will be made a...
Source: BMJ Open - April 19, 2024 Category: General Medicine Tags: Open access Correction Source Type: research

Familial states of primary hyperparathyroidism: an update
AbstractBackgroundFamilial primary hyperparathyroidism (PHPT) includes syndromic and non-syndromic disorders. The former are characterized by the occurrence of PHPT in association with extra-parathyroid manifestations and includes multiple endocrine neoplasia (MEN) types 1, 2, and 4 syndromes, and hyperparathyroidism –jaw tumor (HPT–JT). The latter consists of familial hypocalciuric hypercalcemia (FHH) types 1, 2 and 3, neonatal severe primary hyperparathyroidism (NSHPT), and familial isolated primary hyperparathyroidism (FIHP). The familial forms of PHPT show different levels of PHPT penetrance, developing earlier and...
Source: Journal of Endocrinological Investigation - April 18, 2024 Category: Endocrinology Source Type: research

A prospective cross-sectional study on hypocalcemia after total thyroidectomy in patients with Graves ’ disease: insights on secondary hyperparathyroidism
ConclusionsHyperfunctioning parathyroid glands in the SHPT state were more susceptible to postoperative PTH reduction, which, combined with low preoperative Ca levels, increased the risk of postoperative hypocalcemia in patients with Graves ’ disease. (Source: Surgery Today)
Source: Surgery Today - April 18, 2024 Category: Surgery Source Type: research

Comparative Analysis of Transoral Endoscopic Parathyroidectomy Vestibular Approach and Focused Open Surgery for Primary Hyperparathyroidism Treatment: A Single Center Experience
CONCLUSIONS TOEPVA is a safe method in patients who underwent parthyroid surgery to avoid cervical scarring.PMID:38622842 | DOI:10.12659/MSM.944128 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 16, 2024 Category: Research Authors: Mehmet Zafer Sabuncuoglu Isa Sozen İsmail Zihni Girayhan Celik Nesime Inci Ery ılmaz Fatma Nur Dal Demet Gunduz Ozer Makay Source Type: research

Thoracoscopic resection of paraesophageal ectopic mediastinal parathyroid adenoma in the superior posterior mediastinum: a case report
The ectopic superior parathyroid in the tracheoesophageal groove and paraesophageal region is rare. Hyperparathyroidism results when these glands become hyperfunctioning. That may necessitate surgical interven... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Kai Fu, Xin-Yu Zhu, Xin-Yu Jia, Kun-Peng Feng, Yuan Cui, Jun Zhao and Chang Li Tags: Case Report Source Type: research

Multiple endocrine neoplasia type 1 with MEN1 variant of unknown significance, in a patient after the diagnosed of pancreatic neuroendocrine neoplasia
AbstractDuodenopancreatic neuroendocrine neoplasia (DP-NEN) is in approximately 10% of cases of multiple endocrine neoplasia type 1 (MEN1). We encountered a case in which the onset of NEN led to suspicion and diagnosis of MEN1. Although genetic testing showedMEN1 variant of uncertain significance (VUS), we considered it pathological from the clinical course, promoting the provision of genetic counseling and screening for relatives. MEN1 has a variety of clinical manifestations, and DP-NENs are the second-most common manifestation after primary hyperparathyroidism (pHPT). It is important to assume that MEN1 is an underlying...
Source: International Cancer Conference Journal - April 16, 2024 Category: Cancer & Oncology Source Type: research

The added value of [ < sup > 18 < /sup > F]Fluorocholine PET/TC in the assessment of secondary or tertiary hyperparathyroidism
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2024 Apr 13:500005. doi: 10.1016/j.remnie.2024.500005. Online ahead of print.NO ABSTRACTPMID:38621476 | DOI:10.1016/j.remnie.2024.500005 (Source: Molecular Medicine)
Source: Molecular Medicine - April 15, 2024 Category: Molecular Biology Authors: S Abouzian D A L ópez-Mora A Fern ández-León C Facundo P Stefaneli A Flotats Source Type: research

The added value of [ < sup > 18 < /sup > F]Fluorocholine PET/TC in the assessment of secondary or tertiary hyperparathyroidism
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2024 Apr 13:500005. doi: 10.1016/j.remnie.2024.500005. Online ahead of print.NO ABSTRACTPMID:38621476 | DOI:10.1016/j.remnie.2024.500005 (Source: Molecular Medicine)
Source: Molecular Medicine - April 15, 2024 Category: Molecular Biology Authors: S Abouzian D A L ópez-Mora A Fern ández-León C Facundo P Stefaneli A Flotats Source Type: research

Management of surgical diseases of Primary Hyperparathyroidism: indications of the United Italian Society of Endocrine Surgery (SIUEC)
The objective of this publication was to support surgeons with modern rational protocols of treatment that can be shared by health-care profes sionals, taking into account important clinical, healthcare and therapeutic aspects, as well as potential sequelae and complications. The task force consists of 12 members of the SIUEC highly trained and experienced in thyroid and parathyroid surgery. The main topics concern diagnostic test and loca lization studies, mode of admission and waiting time, therapeutic pathway (patient preparation for surgery, surgical treatment, postoperative management, management of major complication...
Source: Updates in Surgery - April 15, 2024 Category: Surgery Source Type: research

Multiple and hereditary renal tumors: a review for radiologists
Radiologia (Engl Ed). 2024 Mar-Apr;66(2):132-154. doi: 10.1016/j.rxeng.2024.03.001. Epub 2024 Mar 23.ABSTRACT80% of renal carcinomas (RC) are diagnosed incidentally by imaging. 2-4% of "sporadic" multifocality and 5-8% of hereditary syndromes are accepted, probably with underestimation. Multifocality, young age, familiar history, syndromic data, and certain histologies lead to suspicion of hereditary syndrome. Each tumor must be studied individually, with a multidisciplinary evaluation of the patient. Nephron-sparing therapeutic strategies and a radioprotective diagnostic approach are recommended. Relevant data for the rad...
Source: Radiologia - April 13, 2024 Category: Radiology Authors: M Á Corral de la Calle J Encinas de la Iglesia G C Fern ández Pérez A Fraino M Repoll és Cobaleda Source Type: research

Hypovitaminosis D and hyperparathyroidism: a 5-year postoperative follow-up of 30,458 gastric bypass and sleeve gastrectomy patients
CONCLUSIONS: Previous studies alongside these results suggest that RYGB, more so than SG, may cause hypovitaminosis D and thereby hyperparathyroidism, which could lead to osteopenia. The threshold for 25-OH-D should be >75 nmol/L, and despite higher levels, current vitamin D supplementation may not be sufficient. Follow-up should include screening for hyperparathyroidism and hypovitaminosis D.PMID:38614927 | DOI:10.1016/j.soard.2024.02.004 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 13, 2024 Category: Surgery Authors: Katharina Stevens Hella Hultin Magnus Sundbom Source Type: research

Hypovitaminosis D and hyperparathyroidism: a 5-year postoperative follow-up of 30,458 gastric bypass and sleeve gastrectomy patients
CONCLUSIONS: Previous studies alongside these results suggest that RYGB, more so than SG, may cause hypovitaminosis D and thereby hyperparathyroidism, which could lead to osteopenia. The threshold for 25-OH-D should be >75 nmol/L, and despite higher levels, current vitamin D supplementation may not be sufficient. Follow-up should include screening for hyperparathyroidism and hypovitaminosis D.PMID:38614927 | DOI:10.1016/j.soard.2024.02.004 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 13, 2024 Category: Surgery Authors: Katharina Stevens Hella Hultin Magnus Sundbom Source Type: research

Multiple and hereditary renal tumors: a review for radiologists
Radiologia (Engl Ed). 2024 Mar-Apr;66(2):132-154. doi: 10.1016/j.rxeng.2024.03.001. Epub 2024 Mar 23.ABSTRACT80% of renal carcinomas (RC) are diagnosed incidentally by imaging. 2-4% of "sporadic" multifocality and 5-8% of hereditary syndromes are accepted, probably with underestimation. Multifocality, young age, familiar history, syndromic data, and certain histologies lead to suspicion of hereditary syndrome. Each tumor must be studied individually, with a multidisciplinary evaluation of the patient. Nephron-sparing therapeutic strategies and a radioprotective diagnostic approach are recommended. Relevant data for the rad...
Source: Radiologia - April 13, 2024 Category: Radiology Authors: M Á Corral de la Calle J Encinas de la Iglesia G C Fern ández Pérez A Fraino M Repoll és Cobaleda Source Type: research

Hypovitaminosis D and hyperparathyroidism: a 5-year postoperative follow-up of 30,458 gastric bypass and sleeve gastrectomy patients
CONCLUSIONS: Previous studies alongside these results suggest that RYGB, more so than SG, may cause hypovitaminosis D and thereby hyperparathyroidism, which could lead to osteopenia. The threshold for 25-OH-D should be >75 nmol/L, and despite higher levels, current vitamin D supplementation may not be sufficient. Follow-up should include screening for hyperparathyroidism and hypovitaminosis D.PMID:38614927 | DOI:10.1016/j.soard.2024.02.004 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 13, 2024 Category: Surgery Authors: Katharina Stevens Hella Hultin Magnus Sundbom Source Type: research