Research in Maori Community Yields Hope for Huntington’s
I have just returned from a couple weeks in New Zealand, where I am collaborating with Dr. Melanie Cheung and others on a pretty incredible Huntington’s disease project. I am so inspired by what we’re doing there that I wanted to share a bit about it. More than 7,000 of the 4.5 million citizens of […]The post Research in Maori Community Yields Hope for Huntington’s appeared first on "On the Brain" with Dr. Michael Merzenich. (Source: On the Brain by Dr. Michael Merzenich, Ph.D.)
Source: On the Brain by Dr. Michael Merzenich, Ph.D. - February 12, 2015 Category: Neuroscience Authors: Dr. Merzenich Tags: Brain Plasticity Brain Science Cognitive impairments Neuroscience Posit Science HD huntington's maori melanie cheung new zealand Source Type: blogs
Research in Maori Community Yields Hope for Huntington ’ s
I have just returned from a couple weeks in New Zealand, where I am collaborating with Dr. Melanie Cheung and others on a pretty incredible Huntington’s disease project. I am so inspired by what we’re doing there that I wanted to share a bit about it. More than 7,000 of the 4.5 million citizens of […]The post Research in Maori Community Yields Hope for Huntington’s appeared first on "On the Brain" with Dr. Michael Merzenich. (Source: On the Brain by Dr. Michael Merzenich, Ph.D.)
Source: On the Brain by Dr. Michael Merzenich, Ph.D. - February 12, 2015 Category: Neuroscience Authors: Dr. Merzenich Tags: Brain Plasticity Brain Science Cognitive impairments Neuroscience Posit Science HD huntington's maori melanie cheung new zealand Source Type: blogs
The Wheat Belly Total Health Public TV broadcast is coming to your area!
Join me for a provocative and enlightening discussion about why the Wheat Belly lifestyle, coupled with the newest strategies revealed in the Wheat Belly Total Health, can help you achieve levels of health and weight control that you didn’t think were possible!
Here is the November schedule for the Wheat Belly Total Health public television special beginning Saturday, November 29th.
Be sure to show your support for your local public television station by making a generous pledge to allow them to continue to air programs like Wheat Belly Total Health. Special, exclusive-to-public-television Wheat Belly Total Health D...
Source: Wheat Belly Blog - November 25, 2014 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Total Health grains PBS public TV Weight Loss Source Type: blogs
Molecular Chaperones Decline with Age
Chaperone proteins work to ensure correct protein folding and function in cells. The more chaperone activity taking place, the less damage in the form of dysfunctional protein machinery at any given time. Artificially boosting forms of chaperone activity is a potential form of treatment for some of the causes and consequences of age-related degeneration, as it could turn back the clock on rising levels of misfolded and otherwise damaged proteins.
Aging is the most significant and universal risk factor for developing neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Alzheimer's, Parkinson's and Hu...
Source: Fight Aging! - November 4, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Protein Mechanism in Neurodegenerative Diseases
HuntingtinHuntingtin, the abnormal protein that produces clumps characteristic of Huntington disease (HD), can spread from one neuron to another. That's what a recent study has uncovered. Because such protein clumping is observed in other neurodegenerative disorders such as Alzheimer disease (AD) and Parkinson disease (PD), some scientists hope that understanding this newly discovered mechanism of transmission within brain tissue may lead to possible treatments or preventive strategies.If you want to read more about it, check out the resources I've provided below.What can we use from this in teaching undergraduate A&P?...
Source: The A and P Professor - November 3, 2014 Category: Physiology Authors: Kevin Patton Source Type: blogs
An Interesting View of Mitochondrial Damage and Disease
Mitochondria are the bacteria-like power plants of the cell, thousands to each cell, and each mitochondrion bearing its own DNA separate from that in the cell nucleus. Damage to this DNA is important in aging, and in a variety of diseases. Mitochondrial disease and mitochondrial contributions to degenerative aging are two very different things, however, for all that they both involve damage to mitochondrial DNA. In mitochondrial disease most of a patient's mitochondria have the same form of mutational damage, inherited from the mother or generated very early in embryonic growth. In aging the damage is random between cells,...
Source: Fight Aging! - October 27, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
A New Discovery Relating to Heat Shock Factors and Longevity
The heat shock factor HSF-1 is involved in the processes of cellular maintenance relating to ensuring correct protein folding and clearing out misfolded proteins. Protein shape is vital to the operation of cellular machinery, and the presence of misfolded proteins should be considered a form of damage. It has been demonstrated that more HSF-1 extends life and improves tolerance to damage-inducing stress in laboratory animals, and thus a number of research groups are interested in producing treatments based on this effect.
For 35 years, researchers have worked under the assumption that when cells undergo heat shock, as wit...
Source: Fight Aging! - October 17, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Investigating a Repair Mechanism for Stroke Damage
The brain attempts to repair itself following damage such as that caused by a stroke, and researchers continue to discover more about these processes, many of which are still comparatively poorly understood. The near term goal here is to manipulate the underlying biochemistry in order to spur much greater regeneration, possibly not just following injury, but also as a way to offset some of the impact of aging on the brain:
A previously unknown mechanism through which the brain produces new nerve cells after a stroke has been discovered. A stroke is caused by a blood clot blocking a blood vessel in the brain, which leads t...
Source: Fight Aging! - October 16, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
SBA’s Risky Franchise Lending
Nicole Kaeding
The Small Business Administration’s (SBA) stated mission is to aid small businesses and strengthen the economy. Under its popular 7(a) program, SBA provides private lenders with loan guarantees. In the case of default, SBA steps in to cover up to 85percent of the lender’s losses.
This structure encourages lenders to provide more loans, but also encourages the approval of riskier loans. The lenders are insulated from most of the risks of default.
A new analysis conducted by the Wall Street Journal confirms that this arrangement induces SBA to provide loans that result in a large number of defaults...
Source: Cato-at-liberty - September 22, 2014 Category: American Health Authors: Nicole Kaeding Source Type: blogs
MLAPlaydate. Polite, Peaceful, Playful, Powerful Parents & Kids. Info And Photos Of Open Source Activism in BC Education
MLAPlaydate. Polite, Peaceful, Playful, Powerful Parents & Kids. Info And Photos Of Open Source Activism in BC EducationPost from: Adult ADD Strengths
MLAPlaydate. Democracy can be fun if you’re imaginative:)
Here is a bit of background on the open source activism online and offline that Quinn Donovan, I @pqpolitics, & Paul Dayson and many, many other BC parents their children and other citizens made happen online and offline for public education in BC.
Also will list the first day’s media coverage and some tweets with photos of the different MLAPlaydates across BC.
There were 22 MLAPlaydates o...
Source: Adult ADD Strengths - September 18, 2014 Category: Psychiatrists and Psychologists Authors: Pete Quily Tags: ADD / ADHD Advocacy Politics ADHD related Politics Non ADHD Vancouver Source Type: blogs
More on Klotho and Neurodegeneration
High levels of the protein produced by the klotho gene are associated with longevity in mammals, and recently it has also been associated with greater cognitive performance. Here is another small piece of evidence to add to all that:
Alzheimer's disease (AD) is the most frequent age-related dementia affecting 5.4 million Americans including 13 percent of people age 65 and older and more than 40 percent of people over the age of 85. In AD the cognitive decline and dementia result from the death of nerve cells that are involved in learning and memory. The amyloid protein and the excess of the neurotransmitter glutamate are ...
Source: Fight Aging! - July 28, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Kim Teske – Compelling Story of VSED
The Globe & Mail has a very extensive story on Kim Teske and her use of VSED to die on her own terms.
Teske had Huntington’s, an incurable genetic disease that combines aspects of Parkinson’s, Alzheimer’s and schizophrenia. She feared that, if she did not act now, she will end her days in an institution with strangers pushing mush into her mouth and hosing her down after she defecates.
So, Teske stopped eating and drinking. Around noon on day 12 of her fast, Teske died peacefully, with none of the delirium or agitation that some watchers had anticipated. (Sou...
Source: blog.bioethics.net - July 22, 2014 Category: Medical Ethics Authors: Thaddeus Mason Pope Tags: Health Care medical futility blog syndicated Source Type: blogs
Memory Aging and Known Influences on Longevity
This open access review paper looks over some of the better known ways to modestly slow aging and extend healthy life in laboratory animals and their relationship with the progressive degeneration of memory with advancing age:
The aging process has been associated with numerous pathologies at the cellular, tissue, and organ level. Decline or loss of brain functions, including learning and memory, is one of the most devastating and feared aspects of aging. During the past century, age-related memory impairments have emerged as one of the top public health threats. Both psychiatric and neurodegenerative disorders comprising...
Source: Fight Aging! - June 19, 2014 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Hospital Taglines, are they dead?
Last week I read an article in Adweek that touted the “death of the tagline“.
It upset me.
I reluctantly agree that many legacy brands whose taglines propelled them to greatness no longer use them. Apple has not used “Think different” for years. I also concede that most of today’s admired brands, such as Starbucks, Whole Foods, Lululemon, Nordstrom—don’t have them, but invest their messaging efforts towards essence statements, such as Starbucks “rewarding everyday moments’.
I still believe in the power of taglines and their function. Taglines are not dead!
World Class Taglines
Here are...
Source: Nicola Ziady - February 7, 2014 Category: Medical Marketing and PR Authors: Nicola Ziady Tags: Healthcare Marketing Source Type: blogs
