Fourth Pillar or “Third Rail?:” Towards a Community-Centered Understanding of the Role of Molecular HIV Surveillance in Ending the HIV Epidemic in the United States
by Justin C. Smith Molldrem and Smith’s thoughtful article “Reassessing the Ethics of Molecular HIV Surveillance in the Era of Cluster Detection and Response: Toward HIV Data Justice,” calls attention to vitally important considerations in the implementation of molecular HIV surveillance (MHS) in HIV cluster detection response (CDR) efforts. The authors are rightly concerned with the myriad ethical questions posed by how these efforts are carried out, and they echo concerns that some members of the HIV advocacy community in the United States have raised.… (Source: blog.bioethics.net)
Source: blog.bioethics.net - September 25, 2020 Category: Medical Ethics Authors: Blog Editor Tags: Editorial-AJOB Featured Posts HIV/AIDS Technology Source Type: blogs

We Are People, Not Clusters!
by Edwin J. Bernard, Alexander McClelland, Barb Cardell, Cecilia Chung  Marco Castro-Bojorquez, Martin French, Devin Hursey, Naina Khanna, Mx Brian Minalga, Andrew Spieldenner, and Sean Strub As advocates and scholars, including people living with HIV, we have been engaged in a critical debate over molecular HIV surveillance (MHS), as well as its antecedent and future practices. We have elaborated our concerns on the ethical implications and potential harms MHS poses to our communities, in academic fora (Bernard et al. 2007; Chung et al.… (Source: blog.bioethics.net)
Source: blog.bioethics.net - September 25, 2020 Category: Medical Ethics Authors: Blog Editor Tags: Editorial-AJOB Featured Posts HIV/AIDS Technology data informatics MHS Source Type: blogs

Remove Barriers that Prevent Nurses from Addressing Public and Private Health Crises
Michael F. CannonNurses have been on the front line of the COVID-19 pandemic as they have been for every public health crisis from the Spanish influenza to the AIDS epidemic. Yet state governments have made it harder for nurses to help victims of this and other diseases.In 2004, California enacted a law that restricts the ability of hospitals to assign nurses to where patients need them, which increases the cost of care. In that year, California became the first state to mandate inpatient facilities adhere to predeterminednurse ‐​to‐​patient ratios. The law restricts the number of patients each nurse can ...
Source: Cato-at-liberty - September 22, 2020 Category: American Health Authors: Michael F. Cannon Source Type: blogs

Smartphone Video Otoscope To The Rescue: The HearScope Review
Did you know the smallest bones in your body have a super important function? One which you use constantly? The ossicles are just a few millimetres in size, but they help you hear in every second of the day – even when you’re sleeping! Your hearing outer-, middle- and inner ear is a delicate, special system. Examining it requires special skills and a lengthy training. Creating the opportunity to safely observe some parts of this system by non-medical personnel is empowering. This offers a possibility for long distance consultation and telemedicine as well. Source: pinterest.com Is the future of ENT here? ...
Source: The Medical Futurist - September 22, 2020 Category: Information Technology Authors: szandra Tags: Portable Diagnostics Telemedicine & Smartphones device medical device medical technology medical imaging A.I. otoscope hearscope otorhinolaryngology ENT hearables Source Type: blogs

Now Is Not the Time to Forget About the AIDS Epidemic
By SOMA SEN I keep hearing the voices of colleagues and friends that have been part of the AIDS epidemic compare it to the current COVID-19 pandemic. In fact Dr. Kathy Creticos, Director of Infectious Disease at Howard Brown Health spoke about the politicization of both the pandemics.  “Here we are in 2020 with this disease that kills people, that we don’t have any treatments for, that we really don’t understand the full manifestation and presentation biology of the virus,” Creticos said In the final segment of an interview with Contagion during International AIDS Society (IAS) AIDS 2020 Virtual...
Source: The Health Care Blog - September 21, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Public Health AIDS HIV Soma Sen Source Type: blogs

Fight Aging! Newsletter, September 14th 2020
This study is the first to provide a direct link between this inflammation and plaque development - by way of IFITM3. Scientists know that the production of IFITM3 starts in response to activation of the immune system by invading viruses and bacteria. These observations, combined with the new findings that IFITM3 directly contributes to plaque formation, suggest that viral and bacterial infections could increase the risk of Alzheimer's disease development. Indeed, researchers found that the level of IFITM3 in human brain samples correlated with levels of certain viral infections as well as with gamma-secretase activ...
Source: Fight Aging! - September 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Targeting Cellular Senescence to Heal Non-Healing Wounds
An accumulation of senescent cells takes place throughout the body with age. Cells become senescent constantly, the vast majority as a consequence of hitting the Hayflick limit on replication of somatic cells. In youth, these cells are efficiently removed, either via programmed cell death, or destroyed by the immune system. In later life, removal processes slow down, while the damaged state of tissue provokes ever more cells into becoming senescent. In older people, this imbalance leads to a state in which a few percent of all cells in tissues are senescent at any given time. This is, unfortunately, more than enough to pro...
Source: Fight Aging! - September 10, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Mechanisms by which Hearing Loss Might Contribute to the Onset of Dementia
There is a correlation between age-related hearing loss and cognitive decline. Is this because similar mechanisms of cell and tissue damage disrupt both the function of the brain and nerve cells in the ears, or is this because hearing is important in the ongoing operation of the brain? Supporting evidence exists for both options. Here, researchers discuss ways in which loss of hearing might disrupt brain function. Hearing loss in midlife has been estimated to account for 9% of cases of dementia. Acquired hearing loss is most commonly caused by cochlear damage, while dementia is due to cortical degeneration that ty...
Source: Fight Aging! - September 8, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Federal Aid Creates Central ‐​Planning Power
This study argues that Congress should repeal all federal aid-to-state programs for many reasons, including that aid comes with costly strings attached that destroy local democracy.Richard Epstein and Mario Loyolanoted about aid programs: “When Americans vote in state and local elections, they think they are voting on state and local policies. But often they are just deciding which local officials get to implement the dictates of distant and insulated federal bureaucrats, whom even Congress can’t control.”I came across a table (p. 82) in New Jersey ’s budget that lists the $15 billion the state received in 2020 fro...
Source: Cato-at-liberty - September 4, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs

CCR2 Inhibition Promotes Muscle Regeneration in Aged Mice
Chronic inflammation is an important component of aging. The immune system becomes overactive, provoked by a range of problems that include persistent viral infections, increased amounts of molecular debris from dead and damaged cells, and the pro-inflammatory signaling of growing numbers of senescent cells. Inflammation is useful and even necessary in the short term, a part of the defense against pathogens and regeneration from injury. In youth, episodes of inflammation are resolved when no longer needed, but this progressively ceases to be the case in older individuals. Today's open access paper reports on researc...
Source: Fight Aging! - August 31, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

New Cato Book: Ten Global Trends Every Smart Person Should Know: And Many Others You Will Find Interesting
In conclusion, I hope that you will buy this book and share it with your family and friends. It is meant to be a conversation piece. Instead of gathering dust on a bookshelf, it is designed to lie on a living room table (like so many architecture and interior design books), for visitors to see and discuss over a martini or glass of wine. I hope that it will alleviate some depression and anxiety, spark a fact ‐​filled discussion around the dining room table, and maybe even change some minds. Strangers things have happened. Cheers! (Source: Cato-at-liberty)
Source: Cato-at-liberty - August 31, 2020 Category: American Health Authors: Marian L. Tupy Source Type: blogs

Bottom ’s Up: My Addiction Journey
The West Vancouver (Canada) police officer rang the doorbell of my house on Cypress Creek on a fine Tuesday afternoon in April. He told me that a citizen had seen me driving "wildly" the previous Friday afternoon on the Upper Levels Highway and handed me a letter. I thought back to that day. It had started with a large goblet of Chardonnay while making the kids' breakfast. I drove them to school, returned to the house and continued with the white wine. Then I got into the cocaine. Then I was too wired to do anything so I popped a Zopiclone, a tiny blue pill that is guaranteed to put me to sleep no matter ...
Source: PickTheBrain | Motivation and Self Improvement - August 26, 2020 Category: Consumer Health News Authors: Rosemary Keevil Tags: depression family featured psychology addiction anxiety grief recovery Source Type: blogs

Covid-19 and Deafness: Why the Protocols Fall Short
I am hard-of-hearing; I wear two hearing aids, and Covid-19 has made all forms of human interaction extraordinarily difficult. The post Covid-19 and Deafness: Why the Protocols Fall Short appeared first on The Hastings Center. (Source: blog.bioethics.net)
Source: blog.bioethics.net - August 21, 2020 Category: Medical Ethics Authors: Susan Gilbert Tags: Health Care communicating COVID-19 disability Hastings Bioethics Forum Social Distancing syndicated wearing masks Source Type: blogs

TWiV 655: Minority health with Robert Fullilove
Sociomedical scientist Robert Fullilove joins TWiV to discuss disparities in minority health; FDA announces an EUA on Yale’s SalivaDirect, protection of the upper and respiratory tract of mice after intranasal inoculation with an adenovirus-vectored SARS-CoV-2 spike gene, and listener questions. (Source: virology blog)
Source: virology blog - August 21, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus coronavirus COVID-19 HIV/AIDS minority health mucosal immunity pandemic SalivaDirect SARS-CoV-2 vaccine viral viruses Source Type: blogs