Calorie Restriction versus Cancer, Viewed in Terms of Growth Signaling
The practice of calorie restriction, eating fewer calories while still obtaining sufficient micronutrients, is well demonstrated to reduce cancer risk in animal models, and also appears to improve outcomes in the case of an established cancer. This is similarly the case for practices such as intermittent fasting or fasting mimicking diets, the latter having undergone trials as an adjuvant therapy in human cancer patients. Researchers here review this topic through the lens of nutrient sensing and growth signaling in the body, such as the well studied pathways involving growth hormone and IGF-1. More growth means more DNA d...
Source: Fight Aging! - October 18, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
HIV/AIDS vaccine underscores need for better health access
“HIV has been a blessing in my life.” Lola was a 48-year-old woman living in Denver when I interviewed her in 2002 about her HIV-positive diagnosis. She said the diagnosis improved her life in important ways; she had received income and housing support, nutritional assistance, health insurance, medication assistance and primary and infectious disease healthRead more …HIV/AIDS vaccine underscores need for better health access originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 11, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/alyson-odaniel" rel="tag" > Alyson O ’Daniel < /a > < /span > Tags: Policy Infectious Disease Public Health & Source Type: blogs
Fight Aging! Newsletter, September 20th 2021
In conclusion, inhibiting the lysosomal oxidation of LDL in atherosclerotic lesions by antioxidants targeted at lysosomes causes the regression of atherosclerosis and improves liver and muscle characteristics in mice and might be a promising novel therapy for atherosclerosis in patients.
NANOG Expression versus Cellular Senescence
https://www.fightaging.org/archives/2021/09/nanog-expression-versus-cellular-senescence/
Are there many strategies that can reverse cellular senescence? There are certainly strategies that can lower levels of cellular senescence over time, both in cell cultures and in living a...
Source: Fight Aging! - September 19, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards the Regeneration of Hair Cells to Restore Lost Hearing
Loss of hair cells in the inner ear is thought to be the primary mechanism behind the progression of age-related hearing loss, though there is some debate over whether it is in fact loss of cells versus loss of the connections that link hair cells to the brain. For some years, the research community has investigated whether or not it is possible to generate new hair cells in a living animal, bypassing the usual inability to replace losses in this cell population. Various approaches to signaling and cell therapy have been attempted, but despite interesting technology demonstrations, there is as yet little progress towards c...
Source: Fight Aging! - September 17, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Dangers of Disclosure: How HIV Laws Harm Domestic Violence Survivors
Courtney Cross (University of Alabama), The Dangers of Disclosure: How HIV Laws Harm Domestic Violence Survivors, 95 Wash. L. Rev. 83 (2020): People living with HIV or AIDS must decide whether, how, and when to disclose their positive status. State... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - September 13, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Don ’t Read Disparate Impact Into Section 504
Walter Olson and Nicole Saad BembridgeCVS Caremark, a benefits management company pursuing cost containment, introduced rules that require patients using specialty drugs to pay higher prices if they go outside the company ’s in‐house distribution system, specifically its home‐delivery service or pickup at a CVS pharmacy.Five John Doe HIV/AIDS patients who use specialty drugs with employer ‐sponsored healthcare plans sued CVS claiming, firstly, that CVS’s policy change amounts to discrimination under the Affordable Care Act (ACA) by treating consumers of specialty drugs differently from consumer...
Source: Cato-at-liberty - September 10, 2021 Category: American Health Authors: Walter Olson, Nicole Saad Bembridge Source Type: blogs
How To Go Fully Organic + Why Consider Doing So In All Aspects Of Your Lifestyle
When you walk through your local grocery store, maybe you have noticed more spaces and shelves dedicated to organic foods. Organic foods are grown and produced without most pesticides and are free of hormones and antibiotics. The idea of natural resources and healthier options is in high demand - not surprising, with this growth of organic food.
An organic lifestyle means much more than just food, however. For example, you can purchase things for your household that help reduce the amount of waste produced, and you can look for alternate ways of travel that do not leave a carbon footprint.
If you are looking to...
Source: PickTheBrain | Motivation and Self Improvement - August 31, 2021 Category: Consumer Health News Authors: Nicole McCray Tags: featured health and fitness philosophy productivity tips self-improvement better heath organic sustainabl Source Type: blogs
Indian Reservations: Subsidies vs. Property Rights
Chris EdwardsThe proposed Democratic spending planwould provide $20 billion more in subsidies for American Indian programs. Education, health care, and other services on reservations have been appallingly mismanaged for decades. New subsidies may help but they won ’t get at the core problems resulting in reservations being among the poorest places in America.The fundamental issue is the lack of individual property rights on reservations, which undermines incentives for investment and entrepreneurship. Other problems include excessive regulations and mismanagement by federal and tribal bureaucracies, as I examinedin ...
Source: Cato-at-liberty - August 30, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs
Arguing for Economic Inequality Part I: Desert
" Desert " in this context means " people getting what they deserve, " in other words it ' s a subset of the broader idea of justice. The arguments people make in defense of economic inequality are many and varied, but they overlap a good deal and share some assumptions. In substantial part they rely on the pseudoscience of Economics 101. So there ' s a tangled skein to sort out. I ' ve decided to start here.The desert argument is that some people are justly wealthier than others for such reasons as they work harder, or their talents and skills are superior, or they make a greater contribution to society.The first seems tr...
Source: Stayin' Alive - August 30, 2021 Category: American Health Source Type: blogs
Reflection on 40 Years of HIV/AIDS Research
In this jointly written Director ’s Message, NIMH director Dr. Joshua Gordon and Dr. Maureen Goodenow, associate director for AIDS Research and director of the Office of AIDS Research at the National Institutes of Health, discuss 40 years of NIMH and NIH support for HIV/AIDS research. (Source: NIMH Directors Blog)
Source: NIMH Directors Blog - August 9, 2021 Category: Psychiatry Authors: National Institute of Mental Health Source Type: blogs
COVID ’s lab leak theory obscures zoonosis and progression
Even as COVID-19 is found in apes, big cats, minks, domestic cats, other small mammals, and now in U.S. deer, some don ’t want to let go of the insultingly simplistic “lab leak” theory. Do they really think the 1918 influenza and AIDS pandemics (or Ebola, MERS, and SARS ) needed lab mendacity to exist? WeRead more …COVID’s lab leak theory obscures zoonosis and progression originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 7, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/martha-rosenberg" rel="tag" > Martha Rosenberg < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs
Integrating music, movement and stroke rehabilitation, MedRhythms raises $25M to develop and commercialize digital therapeutic
MedRhythms raises 25m to get patients back in tune after a stroke (TechCrunch):
MedRhythms secured $25 million in Series B funding to advance its digital therapy platform aimed at measuring and improving someone’s ability to walk after they have experienced a neurologic injury or disease … Company co-founder and CEO Brian Harris was a neurologic music fellow at Spaulding Rehabilitation Hospital in Boston, treating people with stroke and brain deficits with music. He began getting questions from patients and families on how they could access similar care outside of the hospital. Not seeing a suitable alternative, h...
Source: SharpBrains - August 2, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation brain deficits breakthrough device chronic stroke walking deficits digital therapeutics digital therapy platform electrophysiological entrainment neural circuitry neurologic disorders neur Source Type: blogs
Biden Should Extend a “Public Option” as a Message to “Health Care Royalists ”
By MIKE MAGEE
In this world of political theatrics, with Democratic legislators from Texas forced into exodus to preserve voters’ rights, and Tucker Carlson rantings about Rep. Eric Swalwell riding shirtless on a camel in Qatar streaming relentlessly, Americans can be excused if they missed a substantive and historic news event last week.
On Friday, July 9th, President Biden signed a far-reaching executive order intended to fuel social and economic reform, and in the process created a potential super-highway sized corridor for programs like universal healthcare. In the President’s view, the enemy of the common ma...
Source: The Health Care Blog - July 19, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Politics Public Health Biden Health insurance Mike Magee Public Option Source Type: blogs
Alcohol, Smoking, Drugs: How Technology Can Help
The global statistics on substance use are disquieting. Globally, about 3 million people die every year from alcohol abuse. Tobacco kills up to half of its users – over 8 million people annually. And the UN’s 2021 World Drug Report estimated that around 275 million people used drugs worldwide in 2020, while over 36 million people suffered from drug use disorders.
Disruptive technologies could act only as additional tools for managing preventive or reactive treatment for both victims and physicians next to therapy. Alcohol content-measuring wristbands, smart lighters, nicotine tracking wearables, stop smoking apps, virt...
Source: The Medical Futurist - July 15, 2021 Category: Information Technology Authors: berci.mesko Tags: E-Patients Future of Medicine Future of Pharma Health Sensors & Trackers Portable Medical Diagnostics Security & Privacy Telemedicine & Smartphones Virtual Reality alcohol digital health Innovation smoking technology VR health Source Type: blogs
Which Modified Sgarbossa Rule does this meet? And what is the Rhythm?
A reader sent this ECG and asked " Steve, can this be hyperK? " He sent no clinical information.What do you think?My answer: " This is inferior OMI. " There is LBBB and an with a false negative Modified Sgarbossa. "The rhythm is also interesting, but does not affect the diagnosis of OMI:there are also no P-waves before the QRS complex. The wide complex suggests an idioventricular rhythm, in fact it is an accelerated junctional rhythm followed by Left Bundle Branch Block (LBBB). Idioventricular rhythm would have a slower QRS onset, similar to VT (and it can ' t be VT also because it is too slow).&nbs...
Source: Dr. Smith's ECG Blog - July 13, 2021 Category: Cardiology Authors: Steve Smith Source Type: blogs
