BRAF Mutation in Langerhans Cell HistiocytosisBRAF Mutation in Langerhans Cell Histiocytosis
Children with Langerhans cell histiocytosis (LCH) and the BRAFV600E mutation may be at greater risk for worse outcomes, including permanent injury and poor short-term response to chemotherapy, according to new research from France. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 11, 2016 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Boy with has rare disease LCH causing 'chicken pox' lumps all over his body
Oscar Langham, 10 months old, of Leek, Staffordshire, suffers from Langerhans' cell histiocytosis, a rare disease of the immune cells which causes an angry red rash. (Source: the Mail online | Health)
Source: the Mail online | Health - April 6, 2016 Category: Consumer Health News Source Type: news
Pediatric cancer patients’ art exhibit shows courage and creativity
The artist Henri Matisse once said, “Creativity takes courage.” So does facing cancer as a child. Cancer, creativity and courage merged at a recent exhibit of art by patients of Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Here is a sampling of the patients’ work and what they say about it.
Nate Cavallo, 14, of Lexington, Massachusetts
Sarcoma
Photographs
These were taken on my Make-A-Wish trip to Moorea in French Polynesia. My goal was to experience a magical underwater world, which I’d often dreamed of seeing. It’s great I was able to capture this once-in-a-lifetime experience.
B...
Source: Thrive, Children's Hospital Boston - May 13, 2015 Category: Pediatrics Authors: Irene Sege Tags: Cancer Our patients’ stories Source Type: news
8 Rare 'House, M.D.' Cases That Can Actually Happen (And How To Avoid Them)
"House, M.D.," starring Hugh Laurie as a pill-popping genius, was conceived as the medical version of "Sherlock Holmes" and ran for eight seasons on Fox. Sunday, Nov. 16, marked the 10-year anniversary of the premiere. Though it's easy to look back on the show and focus on some of the unbelievable details of the cases, it might surprise you to learn that "House" was actually much more realistic than you thought.
Yeah, the odds of all these rare medical cases coming to one hospital in New Jersey are pretty slim, but a variety of sources -- including Andrew Holtz, former CNN Medical Correspondent and author of Medical Scien...
Source: Science - The Huffington Post - November 17, 2014 Category: Science Source Type: news
Histiocytosis: Symptoms and Treatment Information
Histiocytosis is also referred to as, "Langerhans Cell Histiocytosis (LCH)," or more formally as, "Histiocytosis X," and represents a group of rare disorders involving specific cells that usually have important roles as part of a person's immune system. (Source: Disabled World)
Source: Disabled World - October 7, 2014 Category: Disability Tags: Autoimmune Diseases Source Type: news
Your NEJM Group Today: Langerhans'-Cell Histiocytosis Image, Draw-a-Child Test, Connecticut Hospitalist Opportunity (FREE)
By the Editors
NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 16, 2014 Category: Primary Care Source Type: news
Boy battling blood disease dies 24 hours after contracting 'infection'
Toddler Max Moment, from Lancashire, died after developing a deadly infection after months of chemotherapy to treat Langerhans Cell Histiocytosis. Just weeks before his death doctors told his parents he was in remission and beating the rare disease. (Source: the Mail online | Health)
Source: the Mail online | Health - July 9, 2014 Category: Consumer Health News Source Type: news
Dying mother's last wish 'to smile in photo with sons' after losing teeth to rare disease
Kelly Murray, from New Whittington in Derbyshire, was diagnosed with the rare disease langerhan cell histiocytosis, which caused the bones in her mouth to disintegrate. (Source: the Mail online | Health)
Source: the Mail online | Health - May 22, 2014 Category: Consumer Health News Source Type: news
Secondary hemophagocytic lymphohistiocytosis (HLH) from a presumed brown recluse spider bite - Dandoy C, Grimley M.
Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We pres... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 22, 2014 Category: Global & Universal Tags: Non-Human Animals and Insects Source Type: news
The girl as delicate as a china doll: Hollie, 4, has bones as fragile as glass that can shatter with the slightest impact
Hollie Hunter from Chester-le-Street, County Durham, suffers from Langerhans' cell histiocytosis, which only affects one in 200,000 children. (Source: the Mail online | Health)
Source: the Mail online | Health - November 4, 2013 Category: Consumer Health News Source Type: news
Longer Treatment For Children With Langerhans Cell Hystiocytosis Improves Survival Rates
A new international study finds that prolonged, intense initial treatment in children with multi-system Langerhans cell histiocytosis (MS-LCH) can achieve survival rates as high as 84 percent - a full 15 percent improvement over the previous clinical trial in this series. The study, LCH-III, is published in Blood, the journal of the American Society of Hematology. It is the third in a series of international randomized clinical trials for LCH that spans twenty years initiated and coordinated by the Histiocyte Society, a group of more than 200 physicians and scientists worldwide... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 31, 2013 Category: Consumer Health News Tags: Lymphoma / Leukemia / Myeloma Source Type: news
Study shows longer treatment for children with langerhans cell hystiocytosis improves survival rates
(Children's National Medical Center) A new international study finds that prolonged, intense initial treatment in children with multi-system Langerhans cell histiocytosis can achieve survival rates as high as 84 percent -- a full 15 percent improvement over the previous clinical trial in this series. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 29, 2013 Category: Global & Universal Source Type: news
What Causes Spontaneous Pneumothorax?
Discussion
“A pneumothorax is a collection of air in the pleural space, and it can be categorized into spontaneous, traumatic or iatrogenic. Spontaneous pneumothorax can be further classified into primary with no clinical evidence of underlying lung disease or secondary due to pre-existing lung disease.”
Spontaneous pneumothorax is a condition that is relatively rare in pediatrics. There is a bimodal age distribution – neonates and late adolescence. It is caused by tearing of the visceral pleural. Clinical signs include chest pain, dyspnea, tachycardia, tracheal deviation towards contralateral side, hypo...
Source: PediatricEducation.org - May 20, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
Rheumatology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Assistant Professor at University of ChicagoEndocardial Calcification in Beh çet ' s Disease. NEJM, 11/2013.A tiger man - sarcoidosis with muscle involvement. Lancet, 12/2012.Raynaud ' s syndrome may lead to acro-osteolysis. Lancet, 06/2012.Vertebra Plana due to Langerhans ' -cell histiocytosis, with Spontaneous Healing. NEJM, 05/2012.Digital Mucous Cyst. NEJM, 04/2012.Post-Traumatic Herniated Cervical Disk. NEJM, 02/2012.Tophaceous Gout. NEJM, 01/2012.Pulmonary Cement Embolism after Vertebroplasty. NEJM, 01/2012.Metastasis of Renal-Cell Carcinoma. NEJM, 10/2011.Gout Nodulosis. NEJM, 09/2...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Rheumatology Source Type: news
