Sclerosing orbital lesions: broadening the differential diagnosis of " idiopathic sclerosing pseudotumor "
Sclerosing orbital lesion(the biopsy revealed it to be Erdheim-Chester disease)Sclerosing lesions of the orbit can present a diagnostic conundrum. Often submitted with a differential diagnosis that includes idiopathic sclerosing pseudotumor, it is incumbent upon the pathologist to rule out other diagnostic possibilities before designating the lesion as idiopathic. In order to survey the range of diagnoses for such specimens, we searched over a 10-year period for specimens submitted to the University of Colorado pathology department which either clinically or pathologically raised the possibility of idiopathic sclerosing ps...
Source: neuropathology blog - April 19, 2019 Category: Radiology Tags: ophthalmic pathology Source Type: blogs
Langerhans cell histiocytosis
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - November 10, 2013 Category: Internists and Doctors of Medicine Tags: miscellaneous Source Type: blogs
Invisible Illnesses and Special Treatment
Two kinds of posts endlessly circulate on Facebook. Both of them are quite whiny. This one popped up yesterday and is representative of the Type 1 post, INVISIBLE ILLNESS and is presented with odd spellings and punctuation exactly as everyone else posts it:
"Ignorant people can be so cruel!! I'm posting this because recently I
have been mocked and laughed at for things beyond my control... I have
three of these illnesses as does some of my friends.... Not one of my
Facebook friends will copy and paste (but I am counting on a true family
member or friend to do it). If you would
be there for me no matter wha...
Source: Had a Dad Alzheimers Blog - July 15, 2013 Category: Dementia Authors: GBP })i({ Source Type: blogs
Paget's disease if Nipple- Review
Clinical:
Approximately 1%–3% of women with adenocarcinoma of the
breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance,
as originally described in 1874, when Sir James Paget recorded that such
lesions may resemble “ordinary chronic eczema” or present as nipple erosion or
ulceration. Paget disease often has a deceptively banal clinical morphology but
should lead the list of differential diagnoses when evaluating unilateral
lesions of the nipple–areola complex in adults.
Paget disease presenting with nipple erosion.
Most women with the histopathologic finding o...
Source: Oncopathology - June 28, 2013 Category: Pathologists Tags: Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma a common misdiagnosis. Source Type: blogs
Paget's disease if Nipple- Review
Clinical:Approximately 1% –3% of women with adenocarcinoma of the breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance, as originally described in 1874, when Sir James Paget recorded that such lesions may resemble “ordinary chronic eczema” or present as nipple erosion or ulceration. Paget disease often has a deceptively banal clinical morphology but should lead the list of differential diagnoses when evaluating unilateral lesions of the nipple–areola complex in adults.Paget disease presenting with nipple erosion. Most women with the histopathologic finding of Paget disease ...
Source: Oncopathology - June 28, 2013 Category: Cancer & Oncology Tags: a common misdiagnosis. breast Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma Source Type: blogs
Sarcoma – Signs, Histology, and Treatment
Pathophysiology of Soft Tissue Sarcoma
1) sarcomas of the soft tissue are a family of neoplasms affecting the soft tissue of the body Causes 2) previous radiation 3) HIV 4) genetic predisposition such as L-Fraumeni syndrome 5) asbestosis 6) congenital immunodeficiences 7) dioxin exposure 8) Herpes virus
Signs and Symptoms
1) most common presentation is an enlarging mass 2) pain 3) neuralgia and neurologic deficits, if the tumor encases a nerve structure 4) metastases are usually via the blood system and most commonly go to the lungs
Characteristic Test Findings
Radiology – mass on MRI
Histology/Gross Pathology
1) m...
Source: Inside Surgery - January 27, 2013 Category: Surgeons Authors: Editor Tags: Oncology angiosarcoma leimyosarcoma malignant fibrous histiocytosis p53 Schwannoma tumor suppressor Source Type: blogs
