Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
Conditions:   Hematopoietic and Lymphoid Cell Neoplasm;   Recurrent Ependymoma;   Recurrent Ewing Sarcoma;   Recurrent Hepatoblastoma;   Recurrent Histiocytic and Dendritic Cell Neoplasm;   Recurrent Langerhans Cell Histiocytosis;   Recurrent Lymphoma;   Recurrent Malignant Germ Cel l Tumor;   Recurrent Malignant Glioma;   Recurrent Malignant Solid Neoplasm;   Recurrent Medulloblastoma;   Recurrent Neuroblastoma;   Recurr...
Source: ClinicalTrials.gov - March 25, 2020 Category: Research Source Type: clinical trials

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
Conditions:   Ectomesenchymoma;   Recurrent Adrenal Gland Pheochromocytoma;   Recurrent Ependymoma;   Recurrent Ewing Sarcoma;   Recurrent Hepatoblastoma;   Recurrent Langerhans Cell Histiocytosis;   Recurrent Malignant Germ Cell Tumor;   Recurrent Malignant Glioma;   Recurrent Medull oblastoma;   Recurrent Melanoma;   Recurrent Neuroblastoma;   Recurrent Non-Hodgkin Lymphoma;   Recurrent Osteosarcoma;   Recurrent Peripheral Primitive Neuroectode...
Source: ClinicalTrials.gov - February 26, 2020 Category: Research Source Type: clinical trials

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)
Conditions:   Recurrent Ependymoma;   Recurrent Ewing Sarcoma;   Recurrent Hepatoblastoma;   Recurrent Langerhans Cell Histiocytosis;   Recurrent Malignant Germ Cell Tumor;   Recurrent Malignant Glioma;   Recurrent Malignant Solid Neoplasm;   Recurrent Medulloblastoma;   Recurrent Ne uroblastoma;   Recurrent Non-Hodgkin Lymphoma;   Recurrent Osteosarcoma;   Recurrent Peripheral Primitive Neuroectodermal Tumor;   Recurrent Rhabdoid Tumor;   R...
Source: ClinicalTrials.gov - December 12, 2019 Category: Research Source Type: clinical trials

AraC for Newly Diagnosed Adult Langerhans Cell Histiocytosis
Condition:   Langerhans Cell Histiocytosis Intervention:   Drug: Cytarabine Sponsor:   Peking Union Medical College Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2019 Category: Research Source Type: clinical trials

Thalidomide, Cyclophosphamide and Dexamethasone for Recurrent/Refractory Adult Langerhans Cell Histiocytosis
Condition:   Langerhans Cell Histiocytosis Intervention:   Drug: thalidomide combined with dexamethasone and cyclophosphamide Sponsor:   Peking Union Medical College Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2019 Category: Research Source Type: clinical trials