High Intensity Focused Ultrasound Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Data-Driven Approach for Estimating Temperature Variations Based on B-mode Ultrasound Images and Changes in Backscattered Energy
Ultrason Imaging. 2024 Jan;46(1):3-16. doi: 10.1177/01617346231205810. Epub 2023 Dec 1.ABSTRACTThermal treatments that use ultrasound devices as a tool have as a key point the temperature control to be applied in a specific region of the patient's body. This kind of procedure requires caution because the wrong regulation can either limit the treatment or aggravate an existing injury. Therefore, determining the temperature in a region of interest in real-time is a subject of high interest. Although this is still an open problem, in the field of ultrasound analysis, the use of machine learning as a tool for both imaging and ...
Source: Ultrasonic Imaging - December 2, 2023 Category: Radiology Authors: Luiz F R Oliveira Felipe M G Fran ça Wagner C A Pereira Source Type: research

High ‐intensity focused ultrasound ablation combined with systemic therapy for unresectable colorectal cancer liver metastasis: A propensity score‐matched analysis
ConclusionsOur study showed that HIFU ablation targeting unresectable CRLM alongside systemic therapy safely and significantly improved local control rates and prolonged mPFS, especially for lesions smaller than 5.0 cm. (Source: Cancer Medicine)
Source: Cancer Medicine - November 30, 2023 Category: Cancer & Oncology Authors: Fei Tang, Qin Zhong, Tingting Ni, Yingbo Xue, Jing Wu, Rong Deng, Qi Zhang, Yan Li, Xuanlu He, Zhenzhou Yang, Yu Zhang Tags: RESEARCH ARTICLE Source Type: research

Anticancer actions of carnosine in cellular models of prostate cancer
In this study, we investigated the effect of carnosine on cell proliferation and metabolism in both a primary cultured androgen-resistant human prostate cancer cell line, PC346Flu1 and murine TRAMP-C1 cells. Our results show that carnosine has a significant dose-dependent inhibitory effect in vitro on the proliferation of both human (PC346Flu1) and murine (TRAMP-C1) prostate cancer cells, which was confirmed in 3D-models of the same cells. Carnosine was also shown to decrease adenosine triphosphate content and reactive species which might have been caused in part by the increase in SIRT3 also shown after carnosine treatmen...
Source: J Cell Mol Med - November 29, 2023 Category: Molecular Biology Authors: K Habra J R D Pearson P Le Vu C Puig-Saenz M J Cripps M A Khan M D Turner C Sale S E B McArdle Source Type: research

Anticancer actions of carnosine in cellular models of prostate cancer
In this study, we investigated the effect of carnosine on cell proliferation and metabolism in both a primary cultured androgen-resistant human prostate cancer cell line, PC346Flu1 and murine TRAMP-C1 cells. Our results show that carnosine has a significant dose-dependent inhibitory effect in vitro on the proliferation of both human (PC346Flu1) and murine (TRAMP-C1) prostate cancer cells, which was confirmed in 3D-models of the same cells. Carnosine was also shown to decrease adenosine triphosphate content and reactive species which might have been caused in part by the increase in SIRT3 also shown after carnosine treatmen...
Source: Molecular Medicine - November 29, 2023 Category: Molecular Biology Authors: K Habra J R D Pearson P Le Vu C Puig-Saenz M J Cripps M A Khan M D Turner C Sale S E B McArdle Source Type: research

Reverse Time Migration and Genetic Algorithms combined for reconstruction in transluminal shear wave elastography: An in silico case study
Ultrasonics. 2023 Nov 25;138:107206. doi: 10.1016/j.ultras.2023.107206. Online ahead of print.ABSTRACTA new reconstruction approach that combines Reverse Time Migration (RTM) and Genetic Algorithms (GAs) is proposed for solving the inverse problem associated with transluminal shear wave elastography. The transurethral identification of the first thermal lesion generated by transrectal High Intensity Focused Ultrasound (HIFU) for the treatment of prostate cancer, was used to preliminarily test in silico the combined reconstruction method. The RTM method was optimised by comparing reconstruction images from several cross-cor...
Source: Ultrasonics - November 26, 2023 Category: Physics Authors: Antonio Gomez Guillermo Rus Nader Saffari Source Type: research

Follow-Up of Men Who Have Undergone Focal Therapy for Prostate Cancer with HIFU-A Real-World Experience
CONCLUSIONS: HIFU as a therapy option for nonmetastatic, significant prostate cancer is effective in the short term for carefully selected patients and shows a low risk of adverse events and side effects.PMID:38002699 | DOI:10.3390/jcm12227089 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - November 25, 2023 Category: Cancer & Oncology Authors: Katharina Sophie Mala Henning Plage Lukas M ödl Sebastian Hofbauer Frank Friedersdorff Martin Schostak Kurt Miller Thorsten Schlomm Hannes Cash Source Type: research