In vitro investigation of the effects of high-intensity therapeutic ultrasound (HITU) in glial tumor cell culture
CONCLUSIONS: Our laboratory analyses offer compelling evidence that HITU is not merely feasible but is also a promising non-invasive approach in the treatment paradigm of brain tumors. Standing distinctively apart from radiotherapy, HITU averts early, or late complications commonly associated with the former. While the path ahead mandates comprehensive research to ascertain its clinical utility, preliminary indications firmly posit HITU as a groundbreaking prospect in the management of brain tumors.PMID:38164850 | DOI:10.26355/eurrev_202312_34785 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - January 2, 2024 Category: Drugs & Pharmacology Authors: K T Ozdemir G Ayberk A Kazanci E Simsek C Kabakci Source Type: research

In vitro investigation of the effects of high-intensity therapeutic ultrasound (HITU) in glial tumor cell culture
CONCLUSIONS: Our laboratory analyses offer compelling evidence that HITU is not merely feasible but is also a promising non-invasive approach in the treatment paradigm of brain tumors. Standing distinctively apart from radiotherapy, HITU averts early, or late complications commonly associated with the former. While the path ahead mandates comprehensive research to ascertain its clinical utility, preliminary indications firmly posit HITU as a groundbreaking prospect in the management of brain tumors.PMID:38164850 | DOI:10.26355/eurrev_202312_34785 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - January 2, 2024 Category: Drugs & Pharmacology Authors: K T Ozdemir G Ayberk A Kazanci E Simsek C Kabakci Source Type: research

Long-term outcome and risk factors of reintervention after high intensity focused ultrasound ablation for uterine fibroids: a systematic review and meta-analysis
CONCLUSION: This meta-analysis showed that the overall reintervention rates after HIFU were acceptable and provided consultative suggestions regarding treatment alternatives for patients with fibroids. Subgroup-analysis revealed that USgHIFU, NPVR ≥ 50%, and hypo-/iso-intensity of fibroids on T2WI were significant factors in reducing reintervention.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42023456094.PMID:38164630 | DOI:10.1080/02656736.2023.2299479 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - January 2, 2024 Category: Internal Medicine Authors: Yuya Dou Lian Zhang Yu Liu Min He Yanzhou Wang Zhibiao Wang Source Type: research

In vitro investigation of the effects of high-intensity therapeutic ultrasound (HITU) in glial tumor cell culture
CONCLUSIONS: Our laboratory analyses offer compelling evidence that HITU is not merely feasible but is also a promising non-invasive approach in the treatment paradigm of brain tumors. Standing distinctively apart from radiotherapy, HITU averts early, or late complications commonly associated with the former. While the path ahead mandates comprehensive research to ascertain its clinical utility, preliminary indications firmly posit HITU as a groundbreaking prospect in the management of brain tumors.PMID:38164850 | DOI:10.26355/eurrev_202312_34785 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - January 2, 2024 Category: Drugs & Pharmacology Authors: K T Ozdemir G Ayberk A Kazanci E Simsek C Kabakci Source Type: research

In vitro investigation of the effects of high-intensity therapeutic ultrasound (HITU) in glial tumor cell culture
CONCLUSIONS: Our laboratory analyses offer compelling evidence that HITU is not merely feasible but is also a promising non-invasive approach in the treatment paradigm of brain tumors. Standing distinctively apart from radiotherapy, HITU averts early, or late complications commonly associated with the former. While the path ahead mandates comprehensive research to ascertain its clinical utility, preliminary indications firmly posit HITU as a groundbreaking prospect in the management of brain tumors.PMID:38164850 | DOI:10.26355/eurrev_202312_34785 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - January 2, 2024 Category: Drugs & Pharmacology Authors: K T Ozdemir G Ayberk A Kazanci E Simsek C Kabakci Source Type: research

Focal therapy with high-intensity focused ultrasound for localized prostate cancer: approval as advanced medical care and future outlook
(Source: Journal of Medical Ultrasonics)
Source: Journal of Medical Ultrasonics - January 1, 2024 Category: Radiology Source Type: research

US-guided high-intensity focused ultrasound in pancreatic cancer treatment: a consensus initiative between Chinese and European HIFU centers
Conclusions: US-guided HIFU for advanced pancreatic cancer addresses treatment goals, available options, success rates, and limitations. As a non-invasive, effective local therapy, complementary to chemotherapy and best supportive care, it plays a pivotal role in pain relief, reducing of tumor volume, and potentially improving survival rates.PMID:38159562 | DOI:10.1080/02656736.2023.2295812 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - December 30, 2023 Category: Internal Medicine Authors: Kun Zhou Holger Strunk Dobromir Dimitrov Joan Vidal-Jove Maria A Gonzalez-Carmona Markus Essler Chengbin Jin Zhechuan Mei Hui Zhu Milka Marinova Source Type: research

Cavitation cloud formation and surface damage of a model stone in a high-intensity focused ultrasound field
Ultrason Sonochem. 2023 Dec 22;102:106738. doi: 10.1016/j.ultsonch.2023.106738. Online ahead of print.ABSTRACTThis work investigates the fundamental role of cavitation bubble clouds in stone comminution by focused ultrasound. The fragmentation of stones by ultrasound has applications in medical lithotripsy for the comminution of kidney stones or gall stones, where their fragmentation is believed to result from the high acoustic wave energy as well as the formation of cavitation. Cavitation is known to contribute to erosion and to cause damage away from the target, yet the exact contribution and mechanisms of cavitation rem...
Source: Ultrasonics Sonochemistry - December 27, 2023 Category: Chemistry Authors: Luc Biasiori-Poulanges Bratislav Luki ć Outi Supponen Source Type: research

Cavitation cloud formation and surface damage of a model stone in a high-intensity focused ultrasound field
Ultrason Sonochem. 2023 Dec 22;102:106738. doi: 10.1016/j.ultsonch.2023.106738. Online ahead of print.ABSTRACTThis work investigates the fundamental role of cavitation bubble clouds in stone comminution by focused ultrasound. The fragmentation of stones by ultrasound has applications in medical lithotripsy for the comminution of kidney stones or gall stones, where their fragmentation is believed to result from the high acoustic wave energy as well as the formation of cavitation. Cavitation is known to contribute to erosion and to cause damage away from the target, yet the exact contribution and mechanisms of cavitation rem...
Source: Ultrasonics Sonochemistry - December 27, 2023 Category: Chemistry Authors: Luc Biasiori-Poulanges Bratislav Luki ć Outi Supponen Source Type: research

High-intensity focused ultrasound —a needleless management for osteoid osteoma: a systematic review
The objective of this study is to review the efficacy and side effects of HIFU in the management of osteoid osteoma. A comprehensive search was conducted in PubMed, Science Direct, and Clinical Key until June 30, 2022. Demographic data, baseline characteristics, success rates, pre- and post-procedure pain scores, recurrences, and complications were recorded. Eleven studies were included in this systematic review. Pooled analysis that involved 186 subjects resulted in an overall success rate of 91.94%. Recurrence was reported in two studies, in which it occurred in 4/177 (2.26%) subjects. Skin burn was found in 1 (0.54%) pa...
Source: Musculoskeletal Surgery - December 27, 2023 Category: Orthopaedics Source Type: research

Histology-based quantification of boiling histotripsy outcomes via ResNet-18 network: Towards mechanical dose metrics
Ultrasonics. 2023 Dec 20;138:107225. doi: 10.1016/j.ultras.2023.107225. Online ahead of print.ABSTRACTThis work was focused on the newly developed ultrasonic approach for non-invasive surgery - boiling histotripsy (BH) - recently proposed for mechanical ablation of tissues using pulsed high intensity focused ultrasound (HIFU). The BH lesion is known to depend in size and shape on exposure parameters and mechanical properties, structure and composition of tissue being treated. The aim of this work was to advance the concept of BH dose by investigating quantitative relationships between the parameters of the lesion, pulsing ...
Source: Ultrasonics - December 23, 2023 Category: Physics Authors: Ekaterina Ponomarchuk Gilles Thomas Minho Song Alisa Krokhmal Anastasia Kvashennikova Yak-Nam Wang Vera Khokhlova Tatiana Khokhlova Source Type: research

Histology-based quantification of boiling histotripsy outcomes via ResNet-18 network: Towards mechanical dose metrics
Ultrasonics. 2023 Dec 20;138:107225. doi: 10.1016/j.ultras.2023.107225. Online ahead of print.ABSTRACTThis work was focused on the newly developed ultrasonic approach for non-invasive surgery - boiling histotripsy (BH) - recently proposed for mechanical ablation of tissues using pulsed high intensity focused ultrasound (HIFU). The BH lesion is known to depend in size and shape on exposure parameters and mechanical properties, structure and composition of tissue being treated. The aim of this work was to advance the concept of BH dose by investigating quantitative relationships between the parameters of the lesion, pulsing ...
Source: Ultrasonics - December 23, 2023 Category: Physics Authors: Ekaterina Ponomarchuk Gilles Thomas Minho Song Alisa Krokhmal Anastasia Kvashennikova Yak-Nam Wang Vera Khokhlova Tatiana Khokhlova Source Type: research

Histology-based quantification of boiling histotripsy outcomes via ResNet-18 network: Towards mechanical dose metrics
Ultrasonics. 2023 Dec 20;138:107225. doi: 10.1016/j.ultras.2023.107225. Online ahead of print.ABSTRACTThis work was focused on the newly developed ultrasonic approach for non-invasive surgery - boiling histotripsy (BH) - recently proposed for mechanical ablation of tissues using pulsed high intensity focused ultrasound (HIFU). The BH lesion is known to depend in size and shape on exposure parameters and mechanical properties, structure and composition of tissue being treated. The aim of this work was to advance the concept of BH dose by investigating quantitative relationships between the parameters of the lesion, pulsing ...
Source: Ultrasonics - December 23, 2023 Category: Physics Authors: Ekaterina Ponomarchuk Gilles Thomas Minho Song Alisa Krokhmal Anastasia Kvashennikova Yak-Nam Wang Vera Khokhlova Tatiana Khokhlova Source Type: research

Histology-based quantification of boiling histotripsy outcomes via ResNet-18 network: Towards mechanical dose metrics
Ultrasonics. 2023 Dec 20;138:107225. doi: 10.1016/j.ultras.2023.107225. Online ahead of print.ABSTRACTThis work was focused on the newly developed ultrasonic approach for non-invasive surgery - boiling histotripsy (BH) - recently proposed for mechanical ablation of tissues using pulsed high intensity focused ultrasound (HIFU). The BH lesion is known to depend in size and shape on exposure parameters and mechanical properties, structure and composition of tissue being treated. The aim of this work was to advance the concept of BH dose by investigating quantitative relationships between the parameters of the lesion, pulsing ...
Source: Ultrasonics - December 23, 2023 Category: Physics Authors: Ekaterina Ponomarchuk Gilles Thomas Minho Song Alisa Krokhmal Anastasia Kvashennikova Yak-Nam Wang Vera Khokhlova Tatiana Khokhlova Source Type: research

Ultrasound monitoring of simultaneous High-Intensity focused ultrasound (HIFU) therapy using Minimum-Peak-Sidelobe coded excitation
In this study, a novel single-transmit bipolar sequence with minimum-peak-sidelobe (MPS) level is developed not only to restore the image quality of US monitoring but also remove acoustic interference from simultaneous HIFU transmission. The proposed MPS code is designed with an equal number of positive and negative bits and the bit duration should be an integer multiple of the period of the HIFU waveform. In addition, different permutations of code sequence are searched in order to obtain the optimal encoding. The received imaging echo is firstly decoded by matched filtering to cancel HIFU interference and to enhance the ...
Source: Ultrasonics - December 22, 2023 Category: Physics Authors: Che-Chou Shen Nien-Hung Wu Source Type: research