Custom ‐Design of Multi‐Stimuli‐Responsive Degradable Silica Nanoparticles for Advanced Cancer‐Specific Chemotherapy
The fundamental design principles governing the use of degradable silica nanoparticles, particularly their responsiveness to endogenous/exogenous stimuli, are meticulously outlined in this review, which delves into the use of these nanoparticles for the integration of chemotherapy and diverse treatment modalities. Additionally, this review highlights potential challenges that may impede future research progress and the translation of these innovative approaches into clinical applications. AbstractChemotherapy is crucial in oncology for combating malignant tumors but often encounters obatacles such as severe adverse effects...
Source: Small - April 23, 2024 Category: Nanotechnology Authors: Junjie Zhang, Jiani Zhou, Longguang Tang, Jiayi Ma, Ying Wang, Hui Yang, Xiaoxiao Wang, Wenpei Fan Tags: Review Source Type: research

Intravoxel incoherent motion (IVIM)-derived perfusion fraction mapping for the visual evaluation of MR-guided high intensity focused ultrasound (MR-HIFU) ablation of uterine fibroids
CONCLUSION: The MR-HIFU treatment effect in uterine fibroids can be visualized using IVIM perfusion fraction mapping, in moderate concordance with contrast enhanced MRI. IVIM perfusion fraction mapping has therefore the potential to serve as a contrast agent-free imaging method to visualize the MR-HIFU treatment progression in uterine fibroids.PMID:38616245 | DOI:10.1080/02656736.2024.2321980 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 14, 2024 Category: Internal Medicine Authors: Derk J Slotman Lambertus W Bartels Ingrid M Nijholt Martijn Froeling Judith A F Huirne Chrit T W Moonen Martijn F Boomsma Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

High intensity focused ultrasound in treating great saphenous vein incompetence: Perioperative and 1-year outcomes
CONCLUSION: These preliminary results suggest that HIFU holds promise for the treatment of GSV incompetence. Further trials are needed to compare it with other techniques and assess long-term outcomes.PMID:38560785 | DOI:10.1177/02683555241243161 (Source: Phlebology)
Source: Phlebology - April 1, 2024 Category: Internal Medicine Authors: Paolo Casoni Daniele Bissacco Matteo Pizzamiglio Emanuele Nanni Source Type: research

Effectiveness and complication rates of high intensity focused ultrasound treatment for abdominal wall endometriosis: A systematic review
Eur J Obstet Gynecol Reprod Biol. 2024 Mar 26;297:15-23. doi: 10.1016/j.ejogrb.2024.03.029. Online ahead of print.ABSTRACTIn this review, a systematic literature search on the effectiveness and complication rates of ultrasound-guided and magnetic resonance-guided high-intensity focused ultrasound (USg-/MRgHIFU) for abdominal wall endometriosis (AWE) was conducted in six databases in May/June 2023. Original articles of (non)randomized trials, cohort studies, case-control studies and case series published in peer-reviewed journals were included. Of the included studies the level of evidence (LoE) and methodological quality u...
Source: Reproductive Biology - March 31, 2024 Category: Reproduction Medicine Authors: Elisabeth R Knorren Larissa A de Ridder Ingrid M Nijholt Jeroen R Dijkstra Manon N G J A Braat Judith A F Huirne Martijn F Boomsma Joke M Schutte Source Type: research