Radiological Findings in a Neonate with Seizure: Discussion Based Approach
Findings:5 day old full term neonate with seizures . MRI shows non hemorrhagic infarction in anteromedial left thalamus with rest grossly normal for age FAQs1. What is the abnormality?Left thalamus in the antero medial nuclei location shows restricted diffusion with reduced ADC values with no haemorrhage / intraventricular bleed/ midline shift/ herniation with unremarkable PCA flow void/ unremarkable watershed zones 2. How do we interpret this?Radiologically could rep overlap of the two most common aetiologies of hypoglycaemia(anteromedial thalamic nuclei +) and HIE (thalam...
Source: Sumer's Radiology Site - October 21, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Cardiology MCQ Test 3
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 ...
Source: Cardiophile MD - October 20, 2017 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Adjusting Neutrophil Behavior to Enhance Stroke Recovery
An emerging theme in regenerative research is the importance of the innate immune system to the mechanisms of tissue maintenance, and researchers have so far found a number of ways in which the behavior of these immune cells might potentially be adjusted in order to enhance healing. The scientific community has made initial strides with macrophages and microglia, shifting the balance of pro-inflammatory versus pro-regenerative cells, and here some of the same high level themes are observed in the response to injury of the innate immune cells known as neutrophils. It matters greatly as to whether these immune cells turn up ...
Source: Fight Aging! - September 21, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How To Clear Four Common Roadblocks to Coverage of Stuttering Treatment
Dealing with fluency issues can be confusing and frustrating for the client and family. Navigating health insurance reimbursement for stuttering treatment can also present challenges for them. In our extensive work with clients who stutter, we’ve learned several tips for getting treatment covered—either initially or through an appeal if the insurance company denies coverage. Ease your clients’ and your own anxiety by learning how to navigate through (or around) these four common insurance roadblocks. Does the policy cover stuttering treatment? Become familiar with an insurance company’s specified benefits to determ...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - September 19, 2017 Category: Speech-Language Pathology Authors: Brooke Leiman Tags: Speech-Language Pathology Fluency Disorders Speech Disorders stuttering Source Type: blogs

Obstruction of Magendie's Foramen :MRI
 Case Report : A 33-year-old woman presented with visual disturbance and balance difficulty on MRI brain shows dilatation of lateral, III and IV ventricles along with periventricular T2/FLAIR hyperintensity. Temporal horns are dilated. Fourth ventricle appears dilated out of propotion along with prominent CSF flow void in the IV ventricle and some enhancement in ependymal surface of IV ventricle. Contour abnormality in the foramen of magendie. These findings are indicative of IV ventricular outflow tract obstruction possibly post infective sequele/arachnoiditis in foramen of magendieTeaching Points:Memb...
Source: Sumer's Radiology Site - September 7, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

FGF21 Promotes Remyelination in the Central Nervous System
In this study, we found that circulating FGF21 promotes OPC proliferation. OPC proliferation was elevated in the spinal cords of mice with toxin-induced demyelination, and this proliferation was inhibited by silencing of FGF21 expression in the pancreas. OPCs expressed β-klotho, an essential coreceptor for FGF21, and inhibition of β-klotho expression in OPCs prevented the increase in OPC proliferation and subsequent remyelination. The results of this study reveal an unexpected role of FGF21, which has been previously characterized as a metabolic regulator. In reviewing previous findings regarding FGF21 function in the CN...
Source: Fight Aging! - August 25, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Snake venom is key ingredient in experimental drug for heart patients
An experimental antiplatelet drug has surprising bite. Based on a protein found in snake venom, the new drug prevented blood clotting in mice without causing excessive bleeding after an injury, according to research published Thursday in the journal Arteriosclerosis, Thrombosis and Vascular Biology. The drug has yet to be tested in humans.Bleeding is a common side effect in the current crop of available antiplatelet drugs, which are usually prescribed for heart patients to prevent blood cells, called platelets, from clumping together and forming clots. Depending on where they occur, clots can lead to a stroke or heart atta...
Source: Medical Hemostat - June 9, 2017 Category: Medical Devices Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs

New AI Program on the Scene for Radiology: Aldoc Medical
Artificial Intelligence is rapidly improving the science of radiology. The latest AI project to revolutionize the field isAldoc Medical, an Israeli-based startup that aims to accelerate a radiologist ’s workload with deep learning algorithms that detect “high-level abnormalities” in medical images.Aldoc zooms in on the aspects of the scan that are most relevant to diagnosis. CEO and founder Elad Walach says that the idea for the technology derived from the high disparity of scans to radiologists. “Over the past few years, the amount of CT and MRI exams have increased dramatically, while the amount of radiologists h...
Source: radRounds - May 12, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs

A 60-something with Syncope, LVH, and convex ST Elevation
Note 2 other similar cases at the bottom that come from my book,The ECG in Acute MI.CaseWhile I was busy seeing patients, a resident brought me this ECG of a 60-something with a history of syncope only. There was no chest pain or SOB at the tim of the ECG:Computerized QTc is 464 msA previous ECG from 8 years prior wasnormal.What do you think?There is sinus rhythm at a rate of nearly 100 (nearly tachycardic)There is 2.5 mm STE in lead V1 and 3 mm in lead V2, withconvexity, and 1.5 mm in V3.This meets " STEMI criteria "However, there is very high voltage, with a very deep S-wave in V2 and tall R-wave in V4.This is ...
Source: Dr. Smith's ECG Blog - April 26, 2017 Category: Cardiology Authors: Steve Smith Source Type: blogs

MR perfusion without contrast (Arterial Spin Labeling, ASL)
Teaching points by Dr MGK Murthy1.  So far, in the absence of better techniques for studying direct neural activity, Science has relied on Vascular supply to regions as an Index , using (a) Gadolinium MRI  (b) Radioactively labeled water (15 O water )imaged with with PET Scanner (c) BOLD techniques of MRI (using Oxygen uptake for e.g.: as in functional MRI) 2. However a new technique now using , Magnetically labeled water molecules(Arterial Spin Labeled, ASL) on MRI scanners to study Brain perfusion ( CBF ,Cerebral Blood Flow) is becoming incre...
Source: Sumer's Radiology Site - April 12, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Roy on the Pros and Cons of Medical Marijuana
Medical marijuana was legalized in Maryland two years ago, and this summer we will be getting our first dispensaries.  Psychiatrists are starting to ask what this means in terms of treating patients.  Roy did a great job summing up some of the research for our colleagues:Unfortunately, because of the many historical restrictions on research, there is increasing amounts of data available, yet few "facts" to go by ("fact" as in "a thing that is indisputably the case"). These data are often viewed from differing perspectives. Such as absolute vs relative risks. Harm reduction vs harm avoidance. Public health vs crim...
Source: Shrink Rap - April 3, 2017 Category: Psychiatry Authors: Dinah Source Type: blogs

Research and Reviews in the Fastlane 176
LITFL: Life in the Fast Lane Medical Blog LITFL: Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the  176th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains  5 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Justin Morgenstern and Chris Ni...
Source: Life in the Fast Lane - March 16, 2017 Category: Emergency Medicine Authors: Justin Morgenstern Tags: Cardiology Clinical Research Emergency Medicine Intensive Care R&R in the FASTLANE EBM literature recommendations research and reviews Source Type: blogs

Research and Reviews in the Fastlane 176
LITFL: Life in the Fast Lane Medical Blog LITFL: Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 176th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 5 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid,  Justin Morgenstern and, of cour...
Source: Life in the Fast Lane - March 16, 2017 Category: Emergency Medicine Authors: Justin Morgenstern Tags: Cardiology Clinical Research Emergency Medicine Intensive Care R&R in the FASTLANE EBM literature recommendations research and reviews Source Type: blogs

Doctors are not God. Even if some patients want them to be.
I am not God. Nor do I want to be, but I feel sometimes that my patients and their families do. When I entered the ICU early that overcast morning I knew judging from the throng of anxious people waiting outside that things were not right. He came to me straight away, his eyes haunting and sunken as if he hadn’t slept for the whole night. His body barely able to support itself and even then leaning against his brother’s supporting arms. “Doctor, please, please save my wife, she is in your hands,” he said with tears welling up in those distraught eyes. He was surrounded by equally lost and desperate looking family m...
Source: Kevin, M.D. - Medical Weblog - March 12, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/shahla-siddiqui" rel="tag" > Shahla Siddiqui, MD < /a > Tags: Physician Intensive care Source Type: blogs

Socialized Medicine: From Anecdote to Data
Last night ’s CNN duel between Senators Bernie Sanders and Ted Cruz on the future of Obamacare was pretty illuminating for a recent arrival to the United States, with Senator Sanders’ playbook all-too-familiar to those of us from the UK.Sanders wants a single-payer socialized healthcare system in the United States, just as we have in Britain. Any objection to that is met with the claim that you are “leaving people to die.” The only alternatives on offer, you would think, are the U.S. system as it exists now, or the UK system. Sanders did not once acknowledge that the UK structure, which is free at the point of use,...
Source: Cato-at-liberty - February 8, 2017 Category: American Health Authors: Ryan Bourne Source Type: blogs