Fight Aging! Newsletter, April 11th 2016
In this study we expanded the study by investigating associations of the rest blood parameters with age, and associations between generations, aiming to seek candidate factors associated with familial longevity. Associations of blood parameters in centenarians (CEN) with their first generation of offspring (F1) and F1 spouses (F1SP) were analyzed.
In this study, using association and further comparison analyses we identified several blood parameters that may contribute to longevity. First, total cholesterol (TC) and triglyceride (TG) increased with age until 80 years, but decreased in centenarians, indicating that l...
Source: Fight Aging! - April 10, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Funtabulously Frivolous Friday Five 140
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 140
Question 1
What would you smoke to bring on acute diffuse alveolar haemorrhage?
+ Reveal the Funtabulous Answer
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Crack
that is…Cocaine. [Reference]
Question 2
What is the more common name for ephelides?
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Source: Life in the Fast Lane - April 8, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five aide's pupil argyll robertson pupil cocaine crack crack cocaine ephelides freckles lhermitte's sign ms multiple sclerosis neurosyphilis nitrous oxide torus transverse myelitis Source Type: blogs
Funtabulously Frivolous Friday Five 139
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 139
Question 1
Who is likely to have given one of the first blood transfusion in the United States (clue: famous surgeon)?
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William Halsted, at the age of 29.
His sister had delivered her first baby and severe haemorrhage followed.
His sister had uncontrolled haemorrhage and others thought ...
Source: Life in the Fast Lane - April 1, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five blood transfusion botulinum botulism FFFF herpes zoster hutchinson sign jarsich-herxheimer melanoma syphilis topagnosis William Halsted Source Type: blogs
Research and Reviews in the Fastlane 126
This article is a well done, RDCT comparing non-dissociative dose intravenous ketamine (0.3 mg/kg) to intravenous morphine (0.1 mg/kg). The authors found no statistically significant difference between the two at 30 minutes. This data gives further credence to the use of ketamine for acute pain relief in the ED though it does not demonstrate superiority.
Recommended by Anand Swaminathan
Cardiology
Kim S, et al. Searching for answers to clinical questions using google versus evidence-based summary resources: a randomized controlled crossover study. Academic medicine : journal of the Association of American Medical Coll...
Source: Life in the Fast Lane - March 16, 2016 Category: Emergency Medicine Authors: Jeremy Fried Tags: Airway Cardiology Emergency Medicine R&R in the FASTLANE EBM Education literature recommendations research and reviews Source Type: blogs
Funtabulously Frivolous Friday Five 135
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 135
Question 1
What was the cause for the most fatalities at Pearl Harbour?
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NOT Thiopental (but the initial trauma or delayed hemorrhagic shock)
It has been a popular myth that Thiopental caused more deaths than the initial trauma but of the 344 patients admitted to the Tripler Army Hospi...
Source: Life in the Fast Lane - February 12, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five Aluminium Anaesthetics Buddy Ebsen FFFF Heidelberg Electric Belt impotence Kehr's sign pearl harbour Princess Diana pulmonary vein splenic rupture thiopental thoracotomy Source Type: blogs
" My Beautiful Broken Brain " Coming to Netflix in Mid-March
" My Beautiful Broken Brain " is a documentary by filmmaker Lotje Sodderland about her life after experiencing an hemorrhagic stroke. It was a Kickstarter-funded project. It is co-directed by Lotje and Sophie Robinson. Both are joined by David Lynch as Executive Directors of the film. < p > Film website: < a href= " http://mybeautifulbrokenbrain.com/ " > My Beautiful Broken Brain < /a > < p > Available on Netflix in mid-March after its SXSW premiere. < p > (Here is an article by Lotje Sodderland written for The Guardian in late November, 2015: < a href= " http://www.theguardian.com/society/2014/nov/22/it-felt-as-if-i-h...
Source: BrainBlog - February 7, 2016 Category: Neurology Source Type: blogs
"My Beautiful Broken Brain" Coming to Netflix in Mid-March
"My Beautiful Broken Brain" is a documentary by filmmaker Lotje Sodderland about her life after experiencing an hemorrhagic stroke. It was a Kickstarter-funded project. It is co-directed by Lotje and Sophie Robinson. Both are joined by David Lynch as Executive Directors of the film. Film website: My Beautiful Broken Brain Available on Netflix in mid-March after its SXSW premiere. (Here is an article by Lotje Sodderland written for The Guardian in late November, 2015: I felt as if I had become fear itself.) (Source: BrainBlog)
Source: BrainBlog - February 7, 2016 Category: Neurology Source Type: blogs
Funtabulously Frivolous Friday Five 134
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 134
Question 1
You do a ketamine sedation and the patient develops laryngeal spasm. What physical manoeuvre can you preform to try and resolve the laryngeal spasm while the nursing staff draw up a paralytic?
+ Reveal the Funtabulous Answer
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Larson’s point or the ‘laryngospasm notch’ [Reference]. Accordi...
Source: Life in the Fast Lane - February 5, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five coffee FFFF fox's sign Hammon's crunch larson's point pancreatitis Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 8
This study found that though it is often associated with coronary artery disease (CAD), it can also occur in those without significant CAD. It was not specifically associated with disease of right coronary artery disease.
This cardioinhibitory response may be a manifestation of the Bezold-Jarisch reflex. Bezold-Jarisch reflex inhibits sympathetic activity (sympathetic withdrawal) and increases parasympathetic activity, resulting in bradycardia, which may be associated with vasodilatation, nausea and hypotension. Bezold-Jarisch has been described in the setting of inferior wall infarction and coronary angiography. Origin...
Source: Cardiophile MD - January 26, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ Cardiology X-ray Featured Source Type: blogs
What Do We Know About Medical Errors Associated With Electronic Medical Records?
By ROSS KOPPEL
Recently, the Journal of Patient Safety published a powerful and important article on the role of EHRs in patient harm, errors and malpractice claims. The article is open access. Electronic Health Record–Related Events in Medical Malpractice Claims by Mark L. Graber, Dana Siegal, Heather Riah, Doug Johnston, and Kathy Kenyon.
The article is remarkable for several reasons:
Considerably over 80% of the reported errors involve horrific patient harm: many deaths, strokes, missed and significantly delayed cancer diagnoses, massive hemorrhage, 10-fold overdoses, ignored or lost critical lab results, ...
Source: The Health Care Blog - January 11, 2016 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs
Should Fluoro be Your New Go-To?
Part Three in a Three-Part Series
This is the third and final part of our series on foreign bodies and fluoroscopy. Click here for part one and here for part two.
This month, we walk you through a step-by-step guide with bonus video footage to aid in your technique. This progressive procedure is absolutely significant to your practice, and we hope you all get a chance to try it.
The Approach
n Identification of foreign body on plain film or ultrasound
n Saphenous or posterior tibial nerve block
n Enlargement of the wound or entrance site using incision...
Source: The Procedural Pause - January 4, 2016 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
This Week in Neuroblunders: Optogenetics Edition
Recent technological developments in neuroscience have enabled rapid advances in our knowledge of how neural circuits function in awake behaving animals. Highly targeted and reversible manipulations using light (optogenetics) or drugs have allowed scientists to demonstrate that activating a tiny population of neurons can evoke specific memories or induce insatiable feeding.But this week we learned these popular and precise brain stimulation and inactivation methods may produce spurious links to behavior!! And that “controlling neurons with light or drugs may affect the brain in more ways than expected”! Who knew that r...
Source: The Neurocritic - December 11, 2015 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Giant T wave inversion
Brief Review
ECG showing deep T wave inversion in anterior wall myocardial infarction
(Click on the image for an enlarged view)
Giant T wave inversion can be broad and deep or just deep T inversions. A depth of T wave of 10 mm or above is generally considered as deep T inversion [1]. Giant T wave inversions with depth of 35 mm have also been described in literature [2]. Deep T inversions without gross increase in width can occur in ischemia and hypertrophic cardiomyopathy. In a study involving 864 patients with hypertrophic cardiomyopathy, 15% had giant T wave inversion [3]. While giant T inversions occurred in about one ...
Source: Cardiophile MD - November 18, 2015 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: ECG / Electrophysiology ECG Library deep T inversion giant T inversion Large T wave inversion Source Type: blogs
Research & Reviews in the Fastlane 107
This study suggests we’re even worse at it when the ED is busy. Researchers looked at 1116 hand hygiene opportunities presented to nurses, physicians and other healthcare professionals and used time to physician assessment as a marker of ED crowding. Mean hand hygiene compliance was only 29% but more worryingly longer mean time to physician assessment and higher nursing hours were associated with even lower compliance (24%). The bottom line? No matter how busy you are, WASH YOUR HANDS!
Recommended by Lauren Westafer, Natalie May
Emergency Medicine
Tseng HJ et al. Imaging Foreign Bodies: Ingested, Aspirated, and...
Source: Life in the Fast Lane - November 4, 2015 Category: Emergency Medicine Authors: Jeremy Fried Tags: Cardiology Education Emergency Medicine Infectious Disease Intensive Care Neurology Pediatrics R&R in the FASTLANE Respiratory Resuscitation clinical critical care EBM FOAM literature recommendations research and reviews Source Type: blogs
