Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: Am J Physiol Cell Ph... - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Long noncoding RNA lncPostn links TGF- β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis
Am J Physiol Cell Physiol. 2023 Dec 25. doi: 10.1152/ajpcell.00515.2023. Online ahead of print.ABSTRACTCardiac fibroblasts are essential for the homeostasis of the extracellular matrix whose remodeling in many cardiovascular diseases leads to fibrosis. Long noncoding RNAs (lncRNAs) are associated with cardiac pathologies, but their functions in cardiac fibroblasts and contributions to cardiac fibrosis remain unclear. Here, we aimed to identify fibroblast-enriched lncRNAs essential in myocardial infarction (MI)-induced fibrosis, and explore the molecular mechanisms responsible for their functions. Global lncRNA profiling wa...
Source: American Journal of Physiology. Cell Physiology - December 25, 2023 Category: Cytology Authors: Lichan Tao Zihan Qin Lin Lin Haoran Guo Zi Liang Tingting Wang Jiani Xu Min Xu Fei Hua Xiong Su Source Type: research
Surgically Resected Cardiac Angiosarcoma: Survival Analysis from the National Cancer Database
J Clin Med. 2023 Dec 18;12(24):7764. doi: 10.3390/jcm12247764.ABSTRACTAngiosarcoma is a rare type of soft-tissue sarcoma arising from endothelial cells. It is considered 'high-grade' by definition, reflecting its aggressive behavior. We sought to investigate the role of surgery in cardiac angiosarcoma, identify late mortality predictors, and identify interactions with other modalities in its treatment using a national dataset. The 2004-2017 National Cancer Database was reviewed for patients with primary cardiac angiosarcoma. Late mortality predictors were evaluated with Kaplan-Meier curves and Cox regression analysis. Surg...
Source: Clinical Lung Cancer - December 23, 2023 Category: Cancer & Oncology Authors: Mohamed Rahouma Massimo Baudo Sherif Khairallah Christopher Lau Mario Gaudino Magdy M El-Sayed Ahmed Akshay Kumar Roberto Lorusso Stephanie L Mick Source Type: research
