Exploring state-of-the-art advances in targeted nanomedicines for managing acute and chronic inflammatory lung diseases
Nanomedicine, Ahead of Print. (Source: Future Medicine: Nanomedicine)
Source: Future Medicine: Nanomedicine - March 28, 2023 Category: Nanotechnology Authors: Sujata Maurya Rashi Srivastava Saniya Arfin Susan Hawthorne Niraj Kumar Jha Kirti Agrawal Sibi Raj Brijesh Rathi Arun Kumar Riya Raj Sharad Agrawal Ana Cl áudia Paiva-Santos Asrar Ahmad Malik Kamal Dua Rakesh Rana Shreesh Ojha Saurabh Kumar Jha Ankur Sha Source Type: research
Exploring state-of-the-art advances in targeted nanomedicines for managing acute and chronic inflammatory lung diseases
Nanomedicine, Ahead of Print. (Source: Nanomedicine)
Source: Nanomedicine - March 28, 2023 Category: Nanotechnology Authors: Sujata Maurya Rashi Srivastava Saniya Arfin Susan Hawthorne Niraj Kumar Jha Kirti Agrawal Sibi Raj Brijesh Rathi Arun Kumar Riya Raj Sharad Agrawal Ana Cl áudia Paiva-Santos Asrar Ahmad Malik Kamal Dua Rakesh Rana Shreesh Ojha Saurabh Kumar Jha Ankur Sha Source Type: research
Correlation Between Toxic Elements and Pesticide Residues in Medicinal Herbs Available in Pharmaceutical Market
Biol Trace Elem Res. 2023 Mar 25. doi: 10.1007/s12011-023-03642-y. Online ahead of print.ABSTRACTThe use of medicinal plants for self-medication of minor health conditions has become a widespread practice in contemporary society. Few consumes, however, question the contamination of these products with toxic factors resulting from the planet's increasingly polluted environment. This paper presents the levels of five toxic elements (As, Cr, Pb, Cd, and Hg) and nine organochlorine pesticides (hexachlorobenzene (HCB), lindane, heptachor, aldrin, dieldrin, endrin, p,p'DDE, p,p'DDD, and p,p'DDT) in 14 brands of regularly consume...
Source: Biological Trace Element Research - March 25, 2023 Category: Biology Authors: Mihaela Mirela Bratu Semaghiul Birghila Corina Birghila Valentina Coatu Diana Andreea Danilov Naliana Lupascu Dan Vasiliu Marius Daniel Radu Source Type: research
Correlation Between Toxic Elements and Pesticide Residues in Medicinal Herbs Available in Pharmaceutical Market
Biol Trace Elem Res. 2023 Mar 25. doi: 10.1007/s12011-023-03642-y. Online ahead of print.ABSTRACTThe use of medicinal plants for self-medication of minor health conditions has become a widespread practice in contemporary society. Few consumes, however, question the contamination of these products with toxic factors resulting from the planet's increasingly polluted environment. This paper presents the levels of five toxic elements (As, Cr, Pb, Cd, and Hg) and nine organochlorine pesticides (hexachlorobenzene (HCB), lindane, heptachor, aldrin, dieldrin, endrin, p,p'DDE, p,p'DDD, and p,p'DDT) in 14 brands of regularly consume...
Source: Biological Trace Element Research - March 25, 2023 Category: Biology Authors: Mihaela Mirela Bratu Semaghiul Birghila Corina Birghila Valentina Coatu Diana Andreea Danilov Naliana Lupascu Dan Vasiliu Marius Daniel Radu Source Type: research
Molecules, Vol. 28, Pages 2811: Understanding the Potential Role of Nanotechnology in Liver Fibrosis: A Paradigm in Therapeutics
Cristina Brisc
The liver is a vital organ that plays a crucial role in the physiological operation of the human body. The liver controls the body’s detoxification processes as well as the storage and breakdown of red blood cells, plasma protein and hormone production, and red blood cell destruction; therefore, it is vulnerable to their harmful effects, making it more prone to illness. The most frequent complications of chronic liver conditions include cirrhosis, fatty liver, liver fibrosis, hepatitis, and illnesses brought on by alcohol and drugs. Hepatic fibrosis involves the activation of hepatic ste...
Source: Molecules - March 20, 2023 Category: Chemistry Authors: Sukhbir Singh Neelam Sharma Saurabh Shukla Tapan Behl Sumeet Gupta Md. Khalid Anwer Celia Vargas-De-La-Cruz Simona Gabriela Bungau Cristina Brisc Tags: Review Source Type: research
Development of a low-dose fipronil deer feed: evaluation of efficacy against two medically important tick species parasitizing white-tailed deer (Odocoileus virginianus) under pen conditions
Odocoileus virginianus (the white-tailed deer) is a key reproductive host for medically important tick species, including Ixodes scapularis and Amblyomma americanum. Orally administering a systemic acaricide to w... (Source: Parasites and Vectors)
Source: Parasites and Vectors - March 9, 2023 Category: Microbiology Authors: David M. Poch é, Donald Wagner, Kylie Green, Zachary Smith, Noah Hawthorne, Batchimeg Tseveenjav and Richard M. Poché Tags: Research Source Type: research
Characterization of procyanidin extracts from hawthorn (Crataegus pinnatifida) in human colorectal adenocarcinoma cell line Caco-2, simulated Digestion, and fermentation identified unique and novel prebiotic properties
This study aims to explore the dynamic changes of HPCs during in vitro digestion and fermentation, as well as their Caco-2 permeability, focusing mainly on the interaction between gut microbiota and HPCs. The results showed that the digested HPC samples had characteristic absorption peaks at 280 nm, and there were absorption peaks in the stretching vibration zone, including OH and CC on the benzene ring, which suggested that procyanidins were the main components in HPCs after in vitro digestion. Meanwhile, HPCs had the highest stability in the oral phase. However, the total procyanidin content of HPCs decreased during gast...
Source: Cell Research - March 4, 2023 Category: Cytology Authors: Xue Han Qian Zhou Zhe Gao Guanying Bianca Xu Hong Chen Bimal Chitrakar Yasai Sun Wen Zhao Xuan Lin Kaixuan Zhou Zhisheng Zhang Source Type: research
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells
In this study, Hawthorn oligomic procyanidins extracts (HPOE) were evaluated for their anticancer activity on colorectal cancer. Our results showed that HPOE arrested HCT116 cells cycle at G2/M phase through P53-Cyclin B pathway and promoted apoptosis partly via mitochondrial (Caspase 9-Caspase 3) and death receptor (Caspase 8-Caspase 3) pathways. Meanwhile, it was found that HPOE aggravated HCT116 cells death through lysosomal vacuolation, which was verified by inhibitor/activator of P53-ILC3 signaling pathway. Taken together, HPOE exerted anticancer effects which lays the foundation for the development of functional food...
Source: Cell Research - January 23, 2023 Category: Cytology Authors: Ya-Sai Sun Zi-Wei Wang Zhe Gao Wen Zhao Kiran Thakur Qian Zhong Zhao-Jun Wei Source Type: research
Ethics and Theoretical Issues in Kidney Xenotransplantation
Xenotransplantation has seen recent global interest peak as a result of several clinical xenotransplants being performed in decedents and a live cardiac recipient. However, underpinning these latest transplants have been decades of invested scientific research programs that have been developing the ideal donor source animals to avoid the overwhelming hyperacute xenograft rejection seen using nongenetically modified animal organs, tissues, and cells. However, this also needs to be undertaken along with the development of safe and efficacious xenotransplantation technologies, immunosuppression, monitoring, disease screening,...
Source: Seminars in Nephrology - January 4, 2023 Category: Urology & Nephrology Authors: Wayne John Hawthorne, Adwin Thomas, Richard N. Pierson Source Type: research
Mapping gestational diabetes in the louisville metro area
Gestational diabetes mellitus (GDM) is the most common complication of pregnancy and can lead to significant maternal and fetal morbidity. Treating GDM requires a multimodal approach including but not limited to: diet, exercise and medication. Access to healthy food, places to exercise, and medication can be limited for many patients. Our aim was to determine how socioeconomic factors impact GDM control. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Emily Root, Jenci Hawthorne, V. Ramsey Aldrich, Mehgan Lazenby, Edward Miller Tags: Poster Session III Source Type: research
Hawthorne Effect: More Than Just Telephones
Ochsner J. 2022 Winter;22(4):286-289. doi: 10.31486/toj.22.5031.NO ABSTRACTPMID:36561101 | PMC:PMC9753954 | DOI:10.31486/toj.22.5031 (Source: Ochsner Journal)
Source: Ochsner Journal - December 23, 2022 Category: General Medicine Authors: Lavern E Nossaman Bobby D Nossaman Source Type: research
