Detection of Subclinical Harlequin Syndrome in Pediatric Patients.
CONCLUSION: Asymmetric effects or distribution of local anesthetic used in thoracic epidurals may result in asymmetric blockade of efferent sympathetic nervous system activity. This may cause differences in temperature between the two sides of the face without unilateral flushing. This phenomenon has previously been termed subclinical harlequin syndrome. Subclinical harlequin syndrome may be more common than anticipated and may be detected by comparing temperature differences in patients. PMID: 32160375 [PubMed - as supplied by publisher] (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - March 10, 2020 Category: Anesthesiology Authors: Rovner MS, Redding AT, Wolf BJ, Wharton JA, Risely CJ, Furse CM Tags: Paediatr Anaesth Source Type: research

Harlequin syndrome caused by isolated focal parasympathetic neuropathy
(Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - November 24, 2019 Category: Research Source Type: research

[Harlequin syndrome after scoliosis surgery].
Abstract Harlequin syndrome is a rare combination of symptoms, characterized by unilateral facial anhidrosis and paleness on the affected side, becoming obvious by contralateral flushing mainly during sports activity. The syndrome is mostly idiopathic, however it is also described as a complication of thoracic surgery, i.e. superior lobectomy. Here, we report on two cases of Harlequin syndrome following scoliosis surgery at the cervicothoracic junction. PMID: 31620827 [PubMed - as supplied by publisher] (Source: Der Orthopade)
Source: Der Orthopade - October 15, 2019 Category: Orthopaedics Authors: Heiler U, Pitzen T, Fetter M, Ruf M Tags: Orthopade Source Type: research

North-south syndrome in veno-arterial extra-corporeal membrane oxygenator: the other Harlequin syndrome.
PMID: 31598907 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - October 8, 2019 Category: Anesthesiology Authors: St-Arnaud C, Thériault MM, Mayette M Tags: Can J Anaesth Source Type: research

North-south syndrome in veno-arterial extra-corporeal membrane oxygenator: the other Harlequin syndrome
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - October 8, 2019 Category: Anesthesiology Source Type: research

Isolated Harlequin Syndrome Following Brachial Plexus Nerve Block via Interscalene Approach: A Case Report.
This article describes an occurrence of harlequin syndrome without observed ptosis or miosis following a postoperative interscalene nerve block. PMID: 31573494 [PubMed] (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - October 4, 2019 Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research

Harlequin Syndrome after Thoracoscopic Repair of a Child with Tracheoesophageal Fistula (TEF)
We report on a newborn with TEF who developed HS after thoracoscopic repair. On the first day of life, the girl (3,480 g, gestation age: 41 week) underwent thoracoscopic repair of a type C esophageal atresia (TEF; OR time 105 minute) without complications. The postoperative course was uneventful, the patient swallowed and thrived well and did not require esophageal dilatations. At 2 years of age, missing facial flushing, transpiration, and warming on the right side of her face during agitation were noticed. As no further intervention was required, the girl and her parents adapted well to the symptoms. Our report shows ...
Source: European Journal of Pediatric Surgery Reports - September 25, 2019 Category: Surgery Authors: Wagner, Richard Lacher, Martin Merkenschlager, Andreas Markel, Moritz Tags: Case Report Source Type: research

Harlequin Syndrome Associated with Erector Spinae Plane Block
(Source: Anesthesiology)
Source: Anesthesiology - August 13, 2019 Category: Anesthesiology Source Type: research

Pure autonomic failure presenting as Harlequin syndrome.
We present a patient with unilateral anhidrosis, contralateral facial flushing and hyperhidrosis consistent with Harlequin syndrome that, over 6 years, progressed to PAF, suggesting that PAF may present with focal autonomic impairment prior to generalized autonomic failure. PMID: 31331696 [PubMed - in process] (Source: Autonomic Neuroscience)
Source: Autonomic Neuroscience - July 26, 2019 Category: Neuroscience Authors: Triplett JD, Benarroch EE, Cutsforth-Gregory JK Tags: Auton Neurosci Source Type: research

Harlequin Syndrome in Acute Thalamic Hemorrhage
We describe a case of Harlequin syndrome with co-existing central first-order Horner syndrome in the setting of a large thalamic hemorrhage with intraventricular extension. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2019 Category: Neurology Authors: Mary Clare McKenna, Poornima Menon, Shane Smyth, Sean Murphy Tags: Case Report Source Type: research

Pure autonomic failure presenting as Harlequin syndrome
We present a patient with unilateral anhidrosis, contralateral facial flushing and hyperhidrosis consistent with Harlequin syndrome that, over 6  years, progressed to PAF, suggesting that PAF may present with focal autonomic impairment prior to generalized autonomic failure. (Source: Autonomic Neuroscience: Basic and Clinical)
Source: Autonomic Neuroscience: Basic and Clinical - June 17, 2019 Category: Neuroscience Authors: James D. Triplett, Eduardo E. Benarroch, Jeremy K. Cutsforth-Gregory Source Type: research

Cross-Field Ventilation for Treatment of Harlequin Syndrome in Traumatic Tracheobronchial Injury Repair Using Intraoperative Venoarterial Extracorporeal Membrane Oxygenation
BLUNT TRAUMA to the thorax can lead to a variety of devastating injuries and accounts for a mortality rate of about 15%.1 Tracheobronchial injuries are often missed on initial evaluation because many patients have nonspecific symptoms, and delay in diagnosis can increase mortality.2 Maintaining adequate oxygenation and ventilation while allowing adequate surgical exposure is a priority and requires a coordinated effort by the perioperative team. The authors describe the case of a patient with traumatic left mainstem bronchus avulsion and tracheal tear who was managed intraoperatively with a combination of venoarterial (VA)...
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 6, 2019 Category: Anesthesiology Authors: Jaeyoon Chung, Mark Berguson, Andrew Mendelson, Rebecca Barnett, Eric Schwenk, Nathaniel R. Evans, Scott W. Cowan, Jordan E. Goldhammer Tags: Case Report Source Type: research

Branch Retinal Vein Occlusion in Ipsilateral Harlequin Syndrome.
Authors: Bräutigam A, Somfai GM, Gerding H PMID: 30999345 [PubMed - in process] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 20, 2019 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Management of paediatric dermatological emergencies
This article looks at conditions which may present in childhood that might require urgent treatment. These include infection, drug reactions, erythroderma, congenital ichthyoses (especially collodian baby and Harlequin ichthyosis), Stevens-Johnson syndrome, toxic epidermal necrolysis, infantile haemangiomas and epidermolysis bullosa. (Source: Paediatrics and Child Health)
Source: Paediatrics and Child Health - January 2, 2019 Category: Pediatrics Authors: Rabia Rashid, Helen Goodyear Tags: Symposium: Dermatology Source Type: research

Unconventional Cannulation Strategy in Peripheral Extracorporeal Membrane Oxygenation to Achieve Central Perfusion and Prevent Differential Hypoxia
VENOARTERIAL EXTRACORPOREAL membrane oxygenation (VA-ECMO) is a therapeutic option increasingly used in the management of patients with cardiac and respiratory failure refractory to maximal conventional treatment.1 However, when the heart recovers and lung function remains poor, patients with peripheral ECMO, especially in the case of femoral VA-ECMO, frequently display a lower partial pressure of oxygen (PaO2) in the upper body than in the lower body, a phenomenon that has been termed differential hypoxia, Harlequin syndrome, or North-South syndrome. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 16, 2018 Category: Anesthesiology Authors: Maria E. Antoniucci, Stefano De Paulis, Francesca Bevilacqua, Maria Calabrese, Gabriella Arlotta, Andrea Scapigliati, Michele Corrado, Sergio Guarneri, Lorenzo Martinelli, Roberto Zamparelli, Franco Cavaliere Tags: Case Report Source Type: research