Cost-effectiveness analysis of single-dose or 2-dose of bivalent, quadrivalent, or nonavalent HPV vaccine in a low/middle-income country setting
CONCLUSION: Oping for 2 doses of 9vHPV vaccine in conjunction with a primary HPV screening represents the most cost-effective option for implementing a school-based HPV vaccination program targeting 12-year-old girls in Thailand. Such findings provide valuable insights for policymakers in the realm of cervical cancer prevention.PMID:38670561 | DOI:10.3802/jgo.2024.35.e85 (Source: Journal of Gynecologic Oncology)
Source: Journal of Gynecologic Oncology - April 26, 2024 Category: OBGYN Authors: Wichai Termrungruanglert Nipon Khemapech Apichai Vasuratna Piyalamporn Havanond Tanitra Tantitamit Source Type: research
Viruses, Vol. 16, Pages 680: Human Papillomavirus and Associated Cancers: A Review
Rysavy
The human papillomavirus is the most common sexually transmitted infection in the world. Most HPV infections clear spontaneously within 2 years of infection; however, persistent infection can result in a wide array of diseases, ranging from genital warts to cancer. Most cases of cervical, anal, and oropharyngeal cancers are due to HPV infection, with cervical cancer being one of the leading causes of cancer death in women worldwide. Screening is available for HPV and cervical cancer, but is not available everywhere, particularly in lower-resource settings. HPV infection disproportionally affects individuals liv...
Source: Viruses - April 26, 2024 Category: Virology Authors: JaNiese E. Jensen Greta L. Becker J. Brooks Jackson Mary B. Rysavy Tags: Review Source Type: research
Intratumoral therapies in head and neck squamous cell carcinoma: A systematic review and future perspectives
Head and neck squamous cell carcinoma (HNSCC) constitute a diverse category of cancer sites, encompassing oral cavity, pharynx, larynx, nasal cavity, and paranasal sinuses [1].These malignancies represent a significant global health challenge, affecting countries at various levels of development. According to data from The Global Cancer Observatory (GLOBOCAN) in 2020, HNSCC ranked as the seventh most common cancer worldwide [2]. Projections for 2030 predict an alarming global rise, primarily driven by tumors associated with the human papillomavirus (HPV)[1]. (Source: Cancer Treatment Reviews)
Source: Cancer Treatment Reviews - April 26, 2024 Category: Cancer & Oncology Authors: Pablo Jim énez-Labaig, Antonio Rullan, Irene Braña, Alberto Hernando-Calvo, Victor Moreno, Bernard Doger, George Bitar, Derfel Ap Dafydd, Alan Melcher, Kevin J. Harrington Tags: Anti-tumour Treatment Source Type: research
Cervical microbiota dysbiosis associated with high-risk Human Papillomavirus infection
In this study we identified significantly lower abundance ofLactobacillus mucosae in women with HR-HPV infection compared to the control group. Furthermore, changes in bacterial diversity were noted inLactobacillus non-dominant (LND) samples compared toLactobacillus-dominant (LD) in both HR-HPV-infected and control groups. LND samples in HR-HPV-infected women exhibited a cervical dysbiotic state, characterized byLactobacillus deficiency. In turn, the LD HR-HPV group showed an overrepresentation ofLactobacillus helveticus. In summary, our study highlighted the distinctive roles ofL.mucosae andL.helveticus in HR-HPV infectio...
Source: PLoS One - April 26, 2024 Category: Biomedical Science Authors: Natalia Zeber-Lubecka Source Type: research
Medical students' knowledge about human papillomavirus (HPV), HPV vaccine and head and neck cancer
Hum Vaccin Immunother. 2024 Dec 31;20(1):2344248. doi: 10.1080/21645515.2024.2344248. Epub 2024 Apr 24.ABSTRACTThe Human Papillomavirus (HPV) is a sexually transmitted infection that significantly affects the population worldwide. HPV preventive methods include vaccination, prophylactics, and education. Different types of cancers associated with HPV usually take years or decades to develop after infections, such as Head and Neck Cancer(HNC). Therefore, HPV prevention can be considered cancer prevention. A sample of medical students in Puerto Rico was evaluated to assess their knowledge about HPV, HPV vaccine, and HNC throu...
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Norangelys Solis-Torres Isardo Braverman-Diaz Luis A Rivera-Morales Jose J Perez-Sanchez Valeria S Perez-Bravo Angel J Neris-Sanchez Alexis Vera Yaritza Diaz-Algorri Source Type: research
PD-L1 Expression in Nonbacterial Chronic Cystitis and Bladder Cancer
CONCLUSIONS: Expression of PD-L1 was detected in a cohort of NCC patients, although the PD-L1 positivity rate was lower than that in BC. Our results demonstrate that the degree of PD-L1 expression in bladder tissue is associated with the presence of viral infections and with the degree of inflammatory infiltration of the bladder wall in both NCC and BC.PMID:38662109 | DOI:10.1007/s00192-024-05782-8 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Inga Kosova Vagan Barsegian Lyudmila Gundorova Dmitriy Kolbasov Source Type: research
Seroprevalence of sexually transmitted infections over 44 years - A cross-sectional study in Sweden
CONCLUSIONS: There was a decrease over time in Chlamydia trachomatis seroprevalence, probably due to contact tracing, testing and early treatment; this might also have affected Mycoplasma genitalium seroprevalence. Despite the reduction, seroprevalences are still high, so continued and new efforts to reduce STI incidence are essential.PMID:38659325 | DOI:10.1177/09564624241248874 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Nirina Andersson Tim Waterboer Elisabet Nylander Annika Idahl Source Type: research
Urine high-risk human papillomavirus testing as an alternative to routine cervical screening: A comparative diagnostic accuracy study of two urine collection devices using a randomised study design trial
CONCLUSIONS: Testing of FVU-device-collected urine for HPV was superior to standard-pot-collected urine in colposcopy attendees and has promising sensitivity for CIN2+ detection. General population HPV testing of FVU-device-collected urine will establish its clinical performance and acceptability as an alternative to routine cervical screening.PMID:38660737 | DOI:10.1111/1471-0528.17831 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 25, 2024 Category: OBGYN Authors: Jennifer C Davies Alexandra Sargent Elisabeth Pinggera Suzanne Carter Clare Gilham Peter Sasieni Emma J Crosbie Source Type: research
Prevalence of high-risk human papillomavirus infection among women with diabetes mellitus in Accra, Ghana
CONCLUSION: Our study points to a high prevalence of hr-HPV among women with DM and highlights a need for glycemic control among them as this could contribute to lowering their odds of hr-HPV infection. The low overall rates of HPV vaccination and prior screening also indicate a need to build capacity and expand the scope of education and services offered to women with DM as regards cervical precancer screening.PMID:38664791 | DOI:10.1186/s12905-024-03078-z (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Yacoba Atiase Kofi Effah Comfort Mawusi Wormenor Ethel Tekpor Esu Aku Catherine Morkli Eunice Boafo Ernest Yorke Robert Aryee Nana Owusu Mensah Essel Stephen Danyo Seyram Kemawor Josephine Akpalu Source Type: research
PD-L1 Expression in Nonbacterial Chronic Cystitis and Bladder Cancer
CONCLUSIONS: Expression of PD-L1 was detected in a cohort of NCC patients, although the PD-L1 positivity rate was lower than that in BC. Our results demonstrate that the degree of PD-L1 expression in bladder tissue is associated with the presence of viral infections and with the degree of inflammatory infiltration of the bladder wall in both NCC and BC.PMID:38662109 | DOI:10.1007/s00192-024-05782-8 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Inga Kosova Vagan Barsegian Lyudmila Gundorova Dmitriy Kolbasov Source Type: research
Seroprevalence of sexually transmitted infections over 44 years - A cross-sectional study in Sweden
CONCLUSIONS: There was a decrease over time in Chlamydia trachomatis seroprevalence, probably due to contact tracing, testing and early treatment; this might also have affected Mycoplasma genitalium seroprevalence. Despite the reduction, seroprevalences are still high, so continued and new efforts to reduce STI incidence are essential.PMID:38659325 | DOI:10.1177/09564624241248874 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Nirina Andersson Tim Waterboer Elisabet Nylander Annika Idahl Source Type: research
Urine high-risk human papillomavirus testing as an alternative to routine cervical screening: A comparative diagnostic accuracy study of two urine collection devices using a randomised study design trial
CONCLUSIONS: Testing of FVU-device-collected urine for HPV was superior to standard-pot-collected urine in colposcopy attendees and has promising sensitivity for CIN2+ detection. General population HPV testing of FVU-device-collected urine will establish its clinical performance and acceptability as an alternative to routine cervical screening.PMID:38660737 | DOI:10.1111/1471-0528.17831 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 25, 2024 Category: OBGYN Authors: Jennifer C Davies Alexandra Sargent Elisabeth Pinggera Suzanne Carter Clare Gilham Peter Sasieni Emma J Crosbie Source Type: research
Viruses, Vol. 16, Pages 667: Unveiling the Role of Human Papillomavirus in Urogenital Carcinogenesis a Comprehensive Review
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Human papillomavirus (HPV), an oncogenic DNA virus, is the most common sexually transmitted virus and significant public health concern globally. Despite the substantial prevalence of HPV infection among men, routine testing remains elusive due to the lack of approved HPV tests and the complexity of detection methods. Various studies have explored the link between HPV and genitourinary cancers, revealing different associations influenced by geographic variation, histological subtype and methodological differences. These findings underscore the importance of further research to elucidate the role of HPV in male urogen...
Source: Viruses - April 25, 2024 Category: Virology Authors: Beliz Bahar Karao ğlan Y üksel Ürün Tags: Review Source Type: research
