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High burden of human papillomavirus infection among men in Guangzhou, South China: Implications for HPV vaccination strategies
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 3, 2024 Category: Allergy & Immunology Authors: Pan LiuXiaohan YangHongyu ZhaoLihua LiangMinchai ChenAihua YinMedical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China Source Type: research

Sexual Health for Transgender and Gender Diverse Individuals
Gynecologists play a critical role in the office evaluation of transgender and gender diverse individuals. This includes the provision of essential healthcare services including the treatment and prevention of human immunodeficiency virus and sexually-transmitted infections and screening for human papillomavirus infection-related diseases and cancers. Caring for patients who identify as transgender or gender diverse (TGD) and who have undergone gender-affirming surgical treatments is challenging due in part to clinical gaps in knowledge resulting from insufficient training and educational resources. A patient-centered appr...
Source: Obstetrics and Gynecology Clinics - April 3, 2024 Category: OBGYN Authors: Jocelyn Wascher, Aniruddha Hazra, Andrew R. Fisher Source Type: research

HPV DNA Testing and Mobile Colposcopy for Cervical Precancer Screening in HIV Positive Women: A Comparison Between Two Settings in Ghana and Recommendation for Screening
CONCLUSIONS: There is a high prevalence of hr-HPV among WLHIV in both rural and urban settings in this study in Ghana. Concurrent HPV DNA testing with a visual inspection method (colposcopy/VIA) reduces loss to follow-up compared to performing HPV DNA testing as a standalone test and recalling hr-HPV positive women for follow up with a visual inspection method. Concurrent HPV DNA testing and a visual inspection method may also pick up precancerous cervical lesions that are hr-HPV negative and may be missed if HPV DNA testing is performed alone.PMID:38563112 | DOI:10.1177/10732748241244678 (Source: Cancer Control)
Source: Cancer Control - April 2, 2024 Category: Cancer & Oncology Authors: Kofi Effah Richard Anthony Ethel Tekpor Joseph E Amuah Comfort M Wormenor Georgina Tay Smith E Y Kraa Angela M Katso Christiana A Akonnor Seyram Kemawor Stephen Danyo Bernard H Atuguba Nana Owusu M Essel Patrick K Akakpo Source Type: research

Human papillomavirus circulating tumor DNA: a diagnostic tool in squamous cell carcinoma of unknown primary —a pilot study
DiscussionctHPVDNA demonstrated good diagnostic accuracy for both known and unknown primaries. Incorporation of ctHPVDNA into the diagnostic algorithm for SCCUP may reduce the need for multiple procedures to establish HPV status. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - April 2, 2024 Category: Cancer & Oncology Source Type: research

An evaluation of the cost of human papilloma virus (HPV) vaccine delivery in Zambia
Human papillomavirus (HPV) is a common sexually transmitted infection and the leading cause of cervical cancer. The HPV vaccine is a safe and effective way to prevent HPV infection. In Zambia, the vaccine is g... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 2, 2024 Category: Infectious Diseases Authors: Moses C Simuyemba, Chitalu M Chama-Chiliba, Abson Chompolola, Aaron Sinyangwe, Abdallah Bchir, Gilbert Asiimwe, Carla Chibwesha and Felix Masiye Tags: Research Source Type: research

For due or overdue cervical cancer screening, direct or opt-in mailing of HPV self-sampling increased screening at 6 mo vs. education
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0019. Online ahead of print.ABSTRACTWiner RL, Lin J, Anderson ML, et al. Strategies to increase cervical cancer screening with mailed human papillomavirus self-sampling kits: a randomized clinical trial. JAMA. 2023;330:1971-1981. 38015219.PMID:38560899 | DOI:10.7326/J24-0019 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Pelin Batur Source Type: research

A case report: recurrent anemia related to long term acyclovir use in a pregnant HIV infected Ugandan
Abstract: This case report describes a pregnant patient with recent diagnosis of Human Immuno-Deficiency Virus (HIV) infection initiated on Anti-Retroviral Therapy (ART) in the second trimester, as well as high dose acyclovir high for large infected genital warts. She had no other HIV related opportunistic infections, and no prior anti tuberculosis treatment or preventive medication. Despite little response to acyclovir, patient was continuing on acyclovir for over 4 months. She subsequently developed recurrent anemia requiring frequent transfusion (14 units in total) over a 6-week period.On stopping acyclovir, the anemia ...
Source: African Health Sciences - April 1, 2024 Category: African Health Authors: Mariam Nambuya, Harriet Mayanja-Kizza Source Type: research

Attitude to cervical cancer screening and human papillomavirus testing experience in self-sampled Nigerian women
Conclusion: There is need for more education to improve the level of awareness and uptake of hr-HPV testing for cervicalcancer in Lagos. Health care providers are not offering cervical cancer screening enough and this needs to be explored more infuture studies.Keywords: Cervical cancer; screening test; cancer screening. (Source: African Health Sciences)
Source: African Health Sciences - April 1, 2024 Category: African Health Authors: Ayokunle M Olumodeji, Ayodeji K Adefemi, Modupe O Adedeji, Ayokunle A Ogunyemi, Ifeanyichukwu A Onyeodi, Kabiru A Rabiu, Olurotimi I Akinola Source Type: research

5. Human Papillomavirus Vaccination Uptake in Adolescent Survivors of Bone Marrow Transplant
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and can lead to cervical, oropharyngeal, and anogenital dysplasia and malignancy. Vaccination against HPV is recommended for all adolescents but is particularly important in patients with a history of bone marrow transplant (BMT) as they can have higher rates of persistent HPV-related disease or secondary cancers. Because of lost or reduced immunity after BMT, patients who previously received the vaccine must be re-vaccinated after transplant. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Aimee Morrison, Kasiani Myers, Tara Streich-Tilles Source Type: research

Alterations of UHRF family Expression and was regulated by High Risk Type HPV16 in Uterine Cervical Cancer
In this study, we analyzed the UHRF family expression in cervical cancers, and it's regulation by human papillomavirus (HPV). Western blotting was performed to analyze protein expression in cervical cancer cell lines. Immunohistochemical analysis were used to investigate the expression of UHRF family and MIB-1 in cervical cancer tissues. Transfection were done for analyze the relationship between UHRF family and HPVs. We showed that NIRF expression was decreased and ICBP90 expression was increased in cervical cancers compared to normal counterparts. Western blotting also showed that NIRF expression was quite low levels, bu...
Source: Experimental Cell Research - March 31, 2024 Category: Cytology Authors: Masafumi Yoshimoto Aoi Tokuda Ayami Eguchi Yoshihiro Nozawa Tsutomu Mori Yuji Yaginuma Source Type: research