Cancers, Vol. 16, Pages 1389: Biphasic Regulation of Apoptosis following Gastric Irreversible Electroporation Using Tissue Immunohistochemistry of Activated Caspase-3 with TUNEL Method
This study aimed to investigate IRE-induced gastric tissue apoptosis in response to changes in the electric field intensity, followed by the repair process. Among the 52 rats used in this study, 24 were used to explore apoptosis, and 28 were used to study regeneration. The apoptosis-to-necrosis ratio of the electrical field strength was evaluated using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling and caspase-3 immunohistochemistry. The size of IRE-induced ulcers in the gastric tissue continuously increased with increasing electrical intensity (r2 = 0.830, p < 0.001)....
Source: Cancers - March 31, 2024 Category: Cancer & Oncology Authors: Han Jo Jeon Hoon Jai Chun Hyuk Soon Choi Bora Keum Hong Bae Kim Jong Hyuk Kim Tags: Article Source Type: research
Gastroprotective Effect of 2,3-Dimethylquinoxaline Against Indomethacin-Induced Gastric Ulcer in Rat
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - March 29, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Helicobacter pylori secretary Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
This study evaluates the role of H. pylori secreted concentrated proteins (HPSCP) related oxidative stress role in NLRP3 inflammasome activation and macrophage differentiation. To perceive the role of ROS/RNS, THP-1 and AGS cells were treated with 10 μM diphenyleneiodonium (DPI), 50 μM salicyl hydroxamic acid (SHX), 5 μM Carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), which are specific inhibitors of NADPH oxidase (NOX), Myeloperoxidase (MPO), and mitochondrial oxidative phosphorylation respectively. Cells were also treated with 10 μM of NOS2 inhibitor l-NMMA and 10 μM of N-acetyl cysteine (NAC), a free ...
Source: Cellular Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Sandeep Kumar Monisha Dhiman Source Type: research
Helicobacter pylori secretary Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
This study evaluates the role of H. pylori secreted concentrated proteins (HPSCP) related oxidative stress role in NLRP3 inflammasome activation and macrophage differentiation. To perceive the role of ROS/RNS, THP-1 and AGS cells were treated with 10 μM diphenyleneiodonium (DPI), 50 μM salicyl hydroxamic acid (SHX), 5 μM Carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), which are specific inhibitors of NADPH oxidase (NOX), Myeloperoxidase (MPO), and mitochondrial oxidative phosphorylation respectively. Cells were also treated with 10 μM of NOS2 inhibitor l-NMMA and 10 μM of N-acetyl cysteine (NAC), a free ...
Source: Cancer Control - March 22, 2024 Category: Cancer & Oncology Authors: Sandeep Kumar Monisha Dhiman Source Type: research
Helicobacter pylori secretary Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
This study evaluates the role of H. pylori secreted concentrated proteins (HPSCP) related oxidative stress role in NLRP3 inflammasome activation and macrophage differentiation. To perceive the role of ROS/RNS, THP-1 and AGS cells were treated with 10 μM diphenyleneiodonium (DPI), 50 μM salicyl hydroxamic acid (SHX), 5 μM Carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), which are specific inhibitors of NADPH oxidase (NOX), Myeloperoxidase (MPO), and mitochondrial oxidative phosphorylation respectively. Cells were also treated with 10 μM of NOS2 inhibitor l-NMMA and 10 μM of N-acetyl cysteine (NAC), a free ...
Source: Cellular Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Sandeep Kumar Monisha Dhiman Source Type: research
Helicobacter pylori secretary Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
This study evaluates the role of H. pylori secreted concentrated proteins (HPSCP) related oxidative stress role in NLRP3 inflammasome activation and macrophage differentiation. To perceive the role of ROS/RNS, THP-1 and AGS cells were treated with 10 μM diphenyleneiodonium (DPI), 50 μM salicyl hydroxamic acid (SHX), 5 μM Carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), which are specific inhibitors of NADPH oxidase (NOX), Myeloperoxidase (MPO), and mitochondrial oxidative phosphorylation respectively. Cells were also treated with 10 μM of NOS2 inhibitor l-NMMA and 10 μM of N-acetyl cysteine (NAC), a free ...
Source: Cancer Control - March 22, 2024 Category: Cancer & Oncology Authors: Sandeep Kumar Monisha Dhiman Source Type: research
Extrahepatic < sup > 90 < /sup > Y Complication; Gastric Ulcer Secondary to < sup > 90 < /sup > Y Therapy for Liver Metastasis Despite Negative Preprocedural Imaging
We present the case of a 66-year-old male who developed a radiation-induced gastric ulcer following 90Y therapy with negative pre-procedural imaging and mapping who was retrospectively found to have an accessory artery from the left hepatic artery to the gastric antrum.PMID:38510819 | PMC:PMC10948730 | DOI:10.1007/s13139-023-00828-z (Source: Molecular Medicine)
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Connor Shea Hannah Lamberg Sevcan Turk Mamadou Sanogo Danielle Turgeon Broko Nojkov Kirk Frey David Raffel Source Type: research
Extrahepatic < sup > 90 < /sup > Y Complication; Gastric Ulcer Secondary to < sup > 90 < /sup > Y Therapy for Liver Metastasis Despite Negative Preprocedural Imaging
We present the case of a 66-year-old male who developed a radiation-induced gastric ulcer following 90Y therapy with negative pre-procedural imaging and mapping who was retrospectively found to have an accessory artery from the left hepatic artery to the gastric antrum.PMID:38510819 | PMC:PMC10948730 | DOI:10.1007/s13139-023-00828-z (Source: Molecular Medicine)
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Connor Shea Hannah Lamberg Sevcan Turk Mamadou Sanogo Danielle Turgeon Broko Nojkov Kirk Frey David Raffel Source Type: research
Endoscopic Ultrasound in Non-healing Gastric Ulcer
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Beyond digestive pathology: endoscopic study in systemic disease
Rev Esp Enferm Dig. 2024 Mar 12. doi: 10.17235/reed.2024.10324/2024. Online ahead of print.ABSTRACTA 77-year-old male patient with heart disease, kidney disease under study, and quiescent multiple myeloma. He presented a 2 years history of weight loss and digestive symptoms. In the endoscopic study, multiple gastric ulcers were observed, whose histological study ruled out the initial suspicion. The patient died a month later from refractory shock.PMID:38469812 | DOI:10.17235/reed.2024.10324/2024 (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - March 12, 2024 Category: Gastroenterology Authors: Marina Jarava Delgado Katherine Milagros G ómez Torres Francisco Gallardo S ánchez Source Type: research
