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A Real-World Observational Study to Evaluate the Safety and Effectiveness of Fluticasone Furoate –Oxymetazoline Fixed Dose Combination Nasal Spray in Patients with Allergic Rhinitis
ConclusionThe fixed-dose combination of once-daily fluticasone furoate and oxymetazoline hydrochloride nasal spray 27.5/50 mcg was effective in relieving the nasal congestion and reduction of TNSS, TOSS and TSS in patients suffering from AR. The combination was safe and well tolerated with no rebound congestion throughout the treatment period. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - January 9, 2024 Category: Drugs & Pharmacology Source Type: research

Dupilumab suppresses relapsing chronic eosinophilic pneumonia with severe asthma
Nagoya J Med Sci. 2023 Nov;85(4):857-865. doi: 10.18999/nagjms.85.4.857.ABSTRACTDupilumab-induced hypereosinophilia is mediated by blockade of the IL-4/IL-13 pathway, which reduces eosinophil migration from peripheral blood. The increase in peripheral blood eosinophils may lead to chronic eosinophilic pneumonia (CEP) and/or eosinophilic granulomatosis with polyangiitis, but a direct causal connection between dupilumab and eosinophilic lung diseases has not been established. A 33-year-old Japanese woman with bronchial asthma since age three was treated with fluticasone propionate plus salmeterol twice daily after several as...
Source: Nagoya Journal of Medical Science - December 29, 2023 Category: International Medicine & Public Health Authors: Nami Masumoto Chiyako Oshikata Ryo Nakadegawa Yuto Motobayashi Reeko Osada Saki Manabe Takeshi Kaneko Naomi Tsurikisawa Source Type: research