Non-Calcifying/Langerhans Cell-Rich Calcifying Epithelial Odontogenic Tumour: A Critical Review of the Rare and Distinctive Entity
ConclusionThe NCLC subtype of CEOT is unique as it contains significant numbers of Langerhans cells and has clinicopathological features distinctive from classic CEOT. (Source: Head and Neck Pathology)
Source: Head and Neck Pathology - November 27, 2023 Category: Pathology Source Type: research
Ultrasound characteristics of breast fibromatosis mimicking carcinoma
CONCLUSION: Some differences were observed between BF and IDC in terms of patient age, lesion size, and US characteristics.PMID:37991026 | DOI:10.1002/jcu.23613 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - November 22, 2023 Category: Cancer & Oncology Authors: Huan-Zhong Su Mei Huang Zhi-Yong Li Jin-Hua Tu Long-Cheng Hong Zuo-Bing Zhang Xiao-Dong Zhang Source Type: research
Ultrasound characteristics of breast fibromatosis mimicking carcinoma
CONCLUSION: Some differences were observed between BF and IDC in terms of patient age, lesion size, and US characteristics.PMID:37991026 | DOI:10.1002/jcu.23613 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - November 22, 2023 Category: Cancer & Oncology Authors: Huan-Zhong Su Mei Huang Zhi-Yong Li Jin-Hua Tu Long-Cheng Hong Zuo-Bing Zhang Xiao-Dong Zhang Source Type: research
Association of hyperparathyroidism and benign fibro-osseous jaw tumors: a 25-year retrospective study at Mayo Clinic
ConclusionPatients with benign jaw tumors including FD, OF, and GCG may have increased risk of PHPT compared to the general population. Surgeons treating these benign tumors need to be cognizant of these findings, obtain appropriate laboratory studies, and incorporate multidisciplinary care including endocrinologists, endocrine surgeons, and maxillofacial surgeons. (Source: Oral and Maxillofacial Surgery)
Source: Oral and Maxillofacial Surgery - November 22, 2023 Category: ENT & OMF Source Type: research
Cytologic analysis of metaplastic breast carcinoma: Review of 66 cases diagnosed at the Institut Curie
CONCLUSIONS: Fine-needle aspiration holds considerable potential as a valid, independent, and complementary approach to histologic examination of MBC.PMID:37987613 | DOI:10.1093/ajcp/aqad144 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 21, 2023 Category: Pathology Authors: Adam Kowalewski Jerzy Klijanienko Source Type: research
Cytologic analysis of metaplastic breast carcinoma: Review of 66 cases diagnosed at the Institut Curie
CONCLUSIONS: Fine-needle aspiration holds considerable potential as a valid, independent, and complementary approach to histologic examination of MBC.PMID:37987613 | DOI:10.1093/ajcp/aqad144 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 21, 2023 Category: Pathology Authors: Adam Kowalewski Jerzy Klijanienko Source Type: research
Cervical Aggressive Fibromatosis Causing Airway Obstruction
We report the case of a 26-year-old Tunisian female who presented with acute obstructive dyspnea and a 3-week history of cervical swelling. The swelling was initially only located in the left submandibular area, it then gradually extended to all the anterior cervical supra- and infrahyoid regions causing a clinical presentation resembling that of obstructive dyspnea, the patient was admitted, and an emergency tracheotomy was performed. Tissue samples were taken, pathological analysis revealed an aggressive case of fibromatosis. The patient was treated with corticosteroids and antihormonal therapy, the fibrous mass shrunk c...
Source: Ear, Nose and Throat Journal - November 10, 2023 Category: ENT & OMF Authors: Azer Chebil Mehdi Hasnaoui Mohamed Masmoudi Abedrraouf Ben Fatma Saida Jerbi Khelifa Mighri Source Type: research
Cervical Aggressive Fibromatosis Causing Airway Obstruction
We report the case of a 26-year-old Tunisian female who presented with acute obstructive dyspnea and a 3-week history of cervical swelling. The swelling was initially only located in the left submandibular area, it then gradually extended to all the anterior cervical supra- and infrahyoid regions causing a clinical presentation resembling that of obstructive dyspnea, the patient was admitted, and an emergency tracheotomy was performed. Tissue samples were taken, pathological analysis revealed an aggressive case of fibromatosis. The patient was treated with corticosteroids and antihormonal therapy, the fibrous mass shrunk c...
Source: Ear, Nose and Throat Journal - November 10, 2023 Category: ENT & OMF Authors: Azer Chebil Mehdi Hasnaoui Mohamed Masmoudi Abedrraouf Ben Fatma Saida Jerbi Khelifa Mighri Source Type: research
Cervical Aggressive Fibromatosis Causing Airway Obstruction
We report the case of a 26-year-old Tunisian female who presented with acute obstructive dyspnea and a 3-week history of cervical swelling. The swelling was initially only located in the left submandibular area, it then gradually extended to all the anterior cervical supra- and infrahyoid regions causing a clinical presentation resembling that of obstructive dyspnea, the patient was admitted, and an emergency tracheotomy was performed. Tissue samples were taken, pathological analysis revealed an aggressive case of fibromatosis. The patient was treated with corticosteroids and antihormonal therapy, the fibrous mass shrunk c...
Source: Ear, Nose and Throat Journal - November 10, 2023 Category: ENT & OMF Authors: Azer Chebil Mehdi Hasnaoui Mohamed Masmoudi Abedrraouf Ben Fatma Saida Jerbi Khelifa Mighri Source Type: research
Cervical Aggressive Fibromatosis Causing Airway Obstruction
We report the case of a 26-year-old Tunisian female who presented with acute obstructive dyspnea and a 3-week history of cervical swelling. The swelling was initially only located in the left submandibular area, it then gradually extended to all the anterior cervical supra- and infrahyoid regions causing a clinical presentation resembling that of obstructive dyspnea, the patient was admitted, and an emergency tracheotomy was performed. Tissue samples were taken, pathological analysis revealed an aggressive case of fibromatosis. The patient was treated with corticosteroids and antihormonal therapy, the fibrous mass shrunk c...
Source: Ear, Nose and Throat Journal - November 10, 2023 Category: ENT & OMF Authors: Azer Chebil Mehdi Hasnaoui Mohamed Masmoudi Abedrraouf Ben Fatma Saida Jerbi Khelifa Mighri Source Type: research
Cervical Aggressive Fibromatosis Causing Airway Obstruction
We report the case of a 26-year-old Tunisian female who presented with acute obstructive dyspnea and a 3-week history of cervical swelling. The swelling was initially only located in the left submandibular area, it then gradually extended to all the anterior cervical supra- and infrahyoid regions causing a clinical presentation resembling that of obstructive dyspnea, the patient was admitted, and an emergency tracheotomy was performed. Tissue samples were taken, pathological analysis revealed an aggressive case of fibromatosis. The patient was treated with corticosteroids and antihormonal therapy, the fibrous mass shrunk c...
Source: Ear, Nose and Throat Journal - November 10, 2023 Category: ENT & OMF Authors: Azer Chebil Mehdi Hasnaoui Mohamed Masmoudi Abedrraouf Ben Fatma Saida Jerbi Khelifa Mighri Source Type: research
PDGFR β signaling cooperates with β-catenin to modulate c-Abl and biologic behavior of desmoid-type fibromatosis
CONCLUSIONS: The β-catenin transcriptional target ABL1 is necessary for proliferation and maintenance of HIF1α in desmoid cells. Regulation of c-Abl activity by PDGF signaling and targeted therapies modulates desmoid cell proliferation, thereby suggesting a reason for variable biologic behavior between tumors, a mechanism for sorafenib activity in desmoids, and markers predictive of outcome in patients.PMID:37943631 | DOI:10.1158/1078-0432.CCR-23-2313 (Source: Cell Research)
Source: Cell Research - November 9, 2023 Category: Cytology Authors: Jia Hu Meera R Hameed Narasimhan P Agaram Karissa A Whiting Li-Xuan Qin Anthony M Villano Rachael B O'Connor Julian M Rozenberg Sonia Cohen Katherine Prendergast Sara Kryeziu Richard L White Mitchell C Posner Nicholas D Socci Mrinal M Gounder Samuel Singe Source Type: research
PDGFR β signaling cooperates with β-catenin to modulate c-Abl and biologic behavior of desmoid-type fibromatosis
CONCLUSIONS: The β-catenin transcriptional target ABL1 is necessary for proliferation and maintenance of HIF1α in desmoid cells. Regulation of c-Abl activity by PDGF signaling and targeted therapies modulates desmoid cell proliferation, thereby suggesting a reason for variable biologic behavior between tumors, a mechanism for sorafenib activity in desmoids, and markers predictive of outcome in patients.PMID:37943631 | DOI:10.1158/1078-0432.CCR-23-2313 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - November 9, 2023 Category: Cancer & Oncology Authors: Jia Hu Meera R Hameed Narasimhan P Agaram Karissa A Whiting Li-Xuan Qin Anthony M Villano Rachael B O'Connor Julian M Rozenberg Sonia Cohen Katherine Prendergast Sara Kryeziu Richard L White Mitchell C Posner Nicholas D Socci Mrinal M Gounder Samuel Singe Source Type: research
PDGFR β signaling cooperates with β-catenin to modulate c-Abl and biologic behavior of desmoid-type fibromatosis
CONCLUSIONS: The β-catenin transcriptional target ABL1 is necessary for proliferation and maintenance of HIF1α in desmoid cells. Regulation of c-Abl activity by PDGF signaling and targeted therapies modulates desmoid cell proliferation, thereby suggesting a reason for variable biologic behavior between tumors, a mechanism for sorafenib activity in desmoids, and markers predictive of outcome in patients.PMID:37943631 | DOI:10.1158/1078-0432.CCR-23-2313 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - November 9, 2023 Category: Cancer & Oncology Authors: Jia Hu Meera R Hameed Narasimhan P Agaram Karissa A Whiting Li-Xuan Qin Anthony M Villano Rachael B O'Connor Julian M Rozenberg Sonia Cohen Katherine Prendergast Sara Kryeziu Richard L White Mitchell C Posner Nicholas D Socci Mrinal M Gounder Samuel Singe Source Type: research
