Living With Cancer: Cancer Humor
Cracking up may be a better option than breaking down, or so three recent books by young people with cancer suggest. (Source: NYT Health)
Source: NYT Health - October 12, 2017 Category: Consumer Health News Authors: SUSAN GUBAR Tags: Breast Cancer Books and Literature Ewing's Sarcoma (Disease) Comedy and Humor Riggs, Nina (1977-2017) Harrison, Teva (1976- ) Ritvo, Max (1990-2016) Source Type: news
Two agents deliver knockout punches to Ewing sarcoma
(Georgetown University Medical Center) When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 3, 2017 Category: Cancer & Oncology Source Type: news
Inhibition of the oncogenic fusion protein EWS-FLI1 causes G2-M cell cycle arrest and enhanced vincristine sensitivity in Ewings sarcoma
Ewing’s sarcoma (ES) is a rare and highly malignant cancer that grows in the bones or surrounding tissues mostly affecting adolescents and young adults. A chimeric fusion between the RNA binding protein EWS and the ETS family transcription factor FLI1 (EWS-FLI1), which is generated from a chromosomal translocation, is implicated in driving most ES cases by modulation of transcription and alternative splicing. The small-molecule YK-4-279 inhibits EWS-FLI1 function and induces apoptosis in ES cells. We aimed to identify both the underlying mechanism of the drug and potential combination therapies that might enhance its...
Source: Signal Transduction Knowledge Environment - October 3, 2017 Category: Science Authors: Zöllner, S. K., Selvanathan, S. P., Graham, G. T., Commins, R. M. T., Hong, S. H., Moseley, E., Parks, S., Haladyna, J. N., Erkizan, H. V., Dirksen, U., Hogarty, M. D., Üren, A., Toretsky, J. A. Tags: STKE Research Articles Source Type: news
Leicester cancer boy heading home after treatment in US
Alex Goodwin, from Rugby, England, was diagnosed with Ewing's Sarcoma last year after months of agony in his joints and muscles. He finished treatment earlier this month and is headed home in August. (Source: the Mail online | Health)
Source: the Mail online | Health - July 28, 2017 Category: Consumer Health News Source Type: news
A protein, a 'molecular staple' and CRISPR to develop an Ewing sarcoma model
(Centro Nacional de Investigaciones Oncol รณ gicas (CNIO)) A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma. The technique, based on CRISPR and described in the pages of Stem Cell Reports, makes it possible to generate cellular models to analyze the mechanisms underlying the origin and progression of this and other diseases, as well as the search for new treatments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 10, 2017 Category: International Medicine & Public Health Source Type: news
' Jumonji' protein key to Ewing's sarcoma rampage
A new study pinpoints a protein that may be essential to Ewing ' s sarcoma metastasis -- when researchers knocked down the protein KDM3A in Ewing ' s sarcoma tumor cells, one of a family known as Jumonji proteins, they also inhibited the cancer ' s metastatic ability. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 24, 2017 Category: Science Source Type: news
'Jumonji' protein key to Ewing's sarcoma rampage
(University of Colorado Anschutz Medical Campus) A University of Colorado Cancer Center study published in the journal Oncogene pinpoints a protein that may be essential to Ewing's sarcoma metastasis -- when researchers knocked down the protein KDM3A in Ewing's sarcoma tumor cells, one of a family known as Jumonji proteins, they also inhibited the cancer's metastatic ability. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 24, 2017 Category: Cancer & Oncology Source Type: news
Make the Diagnosis: High-Tech Cancer Care
(MedPage Today) -- Case Findings:
A 22-year-old male patient faces a total femur amputation after a diagnosis of Ewing ' s sarcoma. However, a surgeon was able to preserve his ability to walk.
What was the strategy? (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 6, 2017 Category: Hematology Source Type: news
Ewing Sarcoma Survivors At Increased Risk for Subsequent Malignancies
Survivors of childhood Ewing sarcoma have substantial risk for late mortality and subsequent neoplasms, according to a long-term follow-up study. (Source: CancerNetwork)
Source: CancerNetwork - March 3, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: News Sarcoma Source Type: news
British boy with cancer could be forced to leave US early
Alex Goodwin, from Rugby, England, was diagnosed with Ewing's Sarcoma last year after months of agony in his joints and muscles. He is mid treatment in Kansas - but may be forced home. (Source: the Mail online | Health)
Source: the Mail online | Health - February 24, 2017 Category: Consumer Health News Source Type: news
Tissue-engineered model developed to study bone-invading tumor
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers have used tissue engineering to create models for studying the bone-destroying activity of tumors such as the aggressive pediatric cancer Ewing's sarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 24, 2017 Category: Cancer & Oncology Source Type: news
A 5-Question Quiz on Sarcoma
Are you up to date on adverse prognostic factors for Ewing sarcoma? Do you know the latest drug approved for metastatic soft-tissue sarcoma? Test your knowledge on sarcoma in our latest quiz. (Source: CancerNetwork)
Source: CancerNetwork - February 5, 2017 Category: Cancer & Oncology Authors: Debra Hughes Tags: Quiz Source Type: news
Epigenetic diversity in childhood cancer
Tumors of the elderly carry many DNA mutations that can influence disease course. In contrast, much fewer genetic variants exist in childhood cancers, leaving their clinical diversity unexplained. This conundrum has now been addressed for Ewing sarcoma: researchers observed unexpected variety in the epigenome of these tumors. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 30, 2017 Category: Science Source Type: news
Epigenetic diversity in childhood cancer
(CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) Tumors of the elderly carry many DNA mutations that can influence disease course. In contrast, much fewer genetic variants exist in childhood cancers, leaving their clinical diversity unexplained. This conundrum has now been addressed for Ewing sarcoma: researchers at St. Anna Children's Cancer Research Institute and CeMM Research Center for Molecular Medicine observed unexpected variety in the epigenome of these tumors. This finding, published in Nature Medicine, provides new perspectives for developing personalized therapies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 30, 2017 Category: Cancer & Oncology Source Type: news
Little Girl Who Battled Pediatric Cancer Sends Message To Trump
Eight-year-old Abriel Bentley knows what it’s like to fight for your life. She was diagnosed with a form of bone cancer called Ewing Sarcoma in Sept. 2015, and after undergoing chemotherapy and surgery on her leg, she went into remission this past summer.
Now the little girl from Scottsdale, Arizona has a new mission: raising awareness around pediatric cancer and helping other kids in this fight. On Jan. 21, her family posted a video on her Facebook page, “Team Abri.”
In the video, Abriel issues a plea to President Donald Trump: “Please help us beat the odds against childhood cancer,” she...
Source: Healthy Living - The Huffington Post - January 26, 2017 Category: Consumer Health News Source Type: news
