Teenager with 'slipped disc' is horrified to be told she actually has cancer that's spread all over her body
Dion Yates, 15, from Moray, Scotland, had been in agony for months before her devastating diagnosis of Ewing's sarcoma, a rare but deadly form of bone cancer that affects young people.  (Source: the Mail online | Health)
Source: the Mail online | Health - October 13, 2014 Category: Consumer Health News Source Type: news

Teenage cancer survivor Kieran Maxwell gets surprise police escort to school ball
Kieran Maxwell, from County Durham, was diagnosed with Ewing's Sarcoma childhood cancer when he was 12, and had an above-knee amputation on his left leg on March 31, 2011 - six months after he was diagnosed. (Source: the Mail online | Health)
Source: the Mail online | Health - July 13, 2014 Category: Consumer Health News Source Type: news

Largest Study of Consolidation Therapy for Ewing's SarcomaLargest Study of Consolidation Therapy for Ewing's Sarcoma
Cyclophosphamide and ifosfamide showed similar cure rates, but long-term effects on fertility and kidney function still require study. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 9, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

'Dad and I always ran together... it was our thing. Now we're running for him': Four children raise £10,000 in memory of runner who died of rare bone cancer at just 51
EXCLUSIVE: Paul O'Byrne from North London died following an 18-month battle with Ewing's Sarcoma. His four children, Laura, Katie, Luke and Frankie mark every Father's Day running in his honour. (Source: the Mail online | Health)
Source: the Mail online | Health - June 16, 2014 Category: Consumer Health News Source Type: news

JCI online ahead of print contents for June 9, 2014
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, June 9, 2014, in the JCI: 'Clinical trial evaluates ex vivo cultured cord blood,' 'Murine model of Ewing's sarcoma reveals tumor origins,' 'Vitamin B12-dependent taurine synthesis regulates growth and bone mass,' 'Hypomorphic PCNA mutation underlies a human DNA repair disorder,' 'Characterization of pandemic influenza immune memory signature after vaccination or infection,' and more. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2014 Category: Global & Universal Source Type: news

Tumor chromosomal translocations reproduced for the first time in human cells
(Centro Nacional de Investigaciones Oncologicas (CNIO)) Scientists from the Spanish National Cancer Research Centre and the Spanish National Cardiovascular Research Centre have been able to reproduce, for the first time in human cells, chromosomal translocations associated with two types of cancer: acute myeloid leukemia and Ewing's sarcoma. The discovery, published today in the journal Nature Communications, opens the door to the development of new therapeutic targets to fight these types of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 3, 2014 Category: Cancer & Oncology Source Type: news

Study: Possible new druggable target in Ewing's Sarcoma
(University of Colorado Denver) A University of Colorado Cancer Center study, recently published in the journal Oncogene, shows that downstream from the oncogenic fusion of gene EWS with FLI1 is a signaling chain that includes microRNA-22 and the gene KDM3A. By targeting these links, researchers hope to break this cancer-causing chain. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 21, 2014 Category: Cancer & Oncology Source Type: news

Children's Cancer target of $1.7 million grant
(University of Utah Health Sciences) CureSearch for Children's Cancer this week awarded researchers at Huntsman Cancer Institute at the University of Utah a $1.73 million grant to test a novel targeted treatment for Ewing sarcoma that hopefully will disrupt the cancer's growth and spread. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 4, 2013 Category: Cancer & Oncology Source Type: news

Cancer shouldn't happen to people as young as me. But it does... and I'm proof you can survive it: Teenage Cancer Trust poster girl Charlotte Newman's harrowing story will give hope to every young sufferer
Charlotte, 23, from Leeds was 21 and in the third year of her law degree when she was diagnosed with bone cancer Ewing's Sarcoma. (Source: the Mail online | Health)
Source: the Mail online | Health - August 18, 2013 Category: Consumer Health News Source Type: news

Blocking The Protein-Protein Interaction Which Causes Ewing Sarcoma
Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Their study, which will be presented at the 2013 annual meeting of the American Society of Clinical Oncology*, provides pre-clinical evidence necessary to initiate a clinical trial... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 17, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Preclinical tests shows agent stops 'slippery' proteins from binding, causing Ewing sarcoma
(Georgetown University Medical Center) Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically. Researchers say the study provides preclinical evidence necessary to initiate a clinical trial. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 15, 2013 Category: Cancer & Oncology Source Type: news

More Realistic Tumor Growth And Response To Anti-Cancer Drugs Using Polymer Scaffolds
Porous polymer scaffolds fabricated to support the growth of biological tissue for implantation may hold the potential to greatly accelerate the development of cancer therapeutics. Researchers at Rice University and the University of Texas MD Anderson Cancer Center in Houston and Mount Sinai Medical Center in New York reported this week that three-dimensional scaffolds used to culture Ewing's sarcoma cells were effective at mimicking the environment in which such tumors develop. Their research appears online this week in the Proceedings of the National Academy of Sciences... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 4, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Mutations In 2 Genes Tied To The Death Of Motor Neurons Associated With ALS
A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases. The same mutation occurred in both genes and led to the abnormal build-up of the proteins inside cells. These proteins play an essential role in normal RNA functioning and have also been linked to cancer, including the Ewing sarcoma, the second most common type of bone cancer in children and adolescents... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2013 Category: Consumer Health News Tags: Muscular Dystrophy / ALS Source Type: news