Discovered a potential treatment option for children with Ewing's sarcoma
(IDIBELL-Bellvitge Biomedical Research Institute) A research consortium made up of the Virgen del Rocio hospital in Seville, Sant Joan de Deu and the Bellvitge Biomedical Research Institute in Barcelona, has found a new therapeutic alternative for children who suffer from a malignant pediatric tumor bone and soft tissue called Ewing's sarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 6, 2015 Category: Cancer & Oncology Source Type: news
EORTC and Univ Oxford launch EUROSARC trial for patients with advanced Ewing Sarcoma
(European Organisation for Research and Treatment of Cancer) EUROSARC, European Clinical trials in Rare Sarcomas within an integrated translational trial network, has launched a phase II trial of Linsitinib for patients with relapsed and/or refractory Ewing Sarcoma. The trial, EORTC 1225 / OCTO 038, aims to establish pharmacodynamic responses in Ewing sarcoma tumors to Linsitinib using functional imaging and biopsies, and toxicity and clinical outcomes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 8, 2015 Category: Global & Universal Source Type: news
How My Husband Transformed My Son's MRI Scans Into Incredible Adventures
My son was 2 years old when he had his first MRI scan. After a long, painful night in the emergency room, a CT scan confirmed what we feared: Andrew had a tumor behind his left eye. An MRI was needed to get a clearer and more detailed picture of the horror we were facing.
On that first occasion, the MRI tech took him out of my arms and I listened to my son shriek my name over and over again with his arms flailing as he was carried down a very long, very white hallway. "Maaaama!! Maaaama!!! Mamaaaa!!!" Hearing his screams left me heartbroken and incredulous. It seemed like unnecessary trauma for a child who had already be...
Source: Healthy Living - The Huffington Post - March 31, 2015 Category: Consumer Health News Source Type: news
Ruth Pearcey diagnosed with bone cancer says amputation means she is finally free
Ruth Pearcey, 21, from Leeds, had her leg amputated to beat Ewing's sarcoma, a rare form of bone cancer. Now, ten years later, she says losing her leg gave her her life back. (Source: the Mail online | Health)
Source: the Mail online | Health - February 11, 2015 Category: Consumer Health News Source Type: news
Serendipity leads to discovery of adult cancer genes in young-adult Ewing Sarcoma
(University of Colorado Denver) A University of Colorado Cancer Center study published in the journal PLoS One finds alterations in expression of genes PIK3R3 and PTEN, more commonly observed in adult tumors, in the rare, young-adult bone cancer Ewing Sarcoma, potentially offering ways to improve therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 3, 2015 Category: Cancer & Oncology Source Type: news
New potential therapeutic strategy against a very aggressive infant bone cancer
Inhibition of Sirtuin1 protein may be a future treatment option for metastatic Ewing sarcoma, researchers report. Ewing's sarcoma is the second most common bone cancer and affects children and adolescents. Currently, if diagnosed in time and there is no metastasis, it can be cured in 80% of cases but between 25% and 30% of cases are diagnosed when there is already metastasized, at which low survival to 30 %. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 29, 2015 Category: Science Source Type: news
New potential therapeutic strategy against a very aggressive infant bone cancer
(IDIBELL-Bellvitge Biomedical Research Institute) Researchers at the Bellvitge Biomedical Research Institute, led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 protein as a future treatment option for metastatic Ewing sarcoma. The results of the study were published in the journal Cancer Research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 29, 2015 Category: Cancer & Oncology Source Type: news
Single genetic abnormality accelerates, removes the brakes on Ewing sarcoma tumor growth
(Massachusetts General Hospital) The genetic abnormality that drives the bone cancer Ewing sarcoma operates through two distinct processes -- both activating genes that stimulate tumor growth and suppressing those that should keep cancer from developing. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 16, 2014 Category: Biology Source Type: news
Hornchurch family desperate to save daughter from cancer are crushing cans to raise pennies
EXCLUSIVE: Joni-Mai Stevens, eight, from Hornchurch, is battling five inoperable tumours on her skull, spine and ribs after rare form of bone cancer, Ewing's Sarcoma, returned for a second time. (Source: the Mail online | Health)
Source: the Mail online | Health - December 8, 2014 Category: Consumer Health News Source Type: news
A noncoding RNA promotes pediatric bone cancer
(Journal of Clinical Investigation) Ewing sarcoma is a cancer of bone or its surrounding soft tissue that primarily affects children and young adults. A new study in the Journal of Clinical Investigation indicates that a long non-coding RNA named Ewing sarcoma-associated transcript 1 contributes to the complex network of changes that occur in Ewing Sarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 17, 2014 Category: Cancer & Oncology Source Type: news
Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis
(St. Jude Children's Research Hospital) An international collaboration has identified frequent mutations in two genes that often occur together in Ewing sarcoma and that define a subtype of the cancer associated with reduced survival. The research, conducted by the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and the Institut Curie-Inserm through the International Cancer Genome Consortium, appears in the current issue of the scientific journal Cancer Discovery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2014 Category: Global & Universal Source Type: news
Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project and Institut Curie-Inserm lead collaboration that lays the foundation for precision medicine against bone and soft tissue tumor (Source: St. Jude Children's Research Hospital)
Source: St. Jude Children's Research Hospital - November 12, 2014 Category: Pediatrics Source Type: news
"Gene Sequencing Projects Link Two Mutations to Ewing Sarcoma Subtype with Poor Prognosis," St. Jude Children’s Research Center/The University of Tennessee Health Science Center
An international collaboration has identified frequent mutations in two genes that often occur together in Ewing sarcoma (EWS) and that define a subtype of the cancer associated with reduced survival. The research, conducted by the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and the Institut Curie-Inserm through the International Cancer Genome Consortium, appears in the current issue of the scientific journal Cancer Discovery.
St. Jude Children'... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - November 12, 2014 Category: Cancer & Oncology Source Type: news
Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project and Institut Curie-Inserm lead collaboration that lays the foundation for precision medicine against bone and soft tissue tumor (Source: St. Jude Children's Research Hospital)
Source: St. Jude Children's Research Hospital - November 12, 2014 Category: Pediatrics Source Type: news
