Neutralizing Antibodies Against Enteroviruses in HFM Disease Neutralizing Antibodies Against Enteroviruses in HFM Disease
A better understanding of neutralizing antibody responses in hand foot and mouth disease could have important implications for vaccine development.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 19, 2020 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Emergency Use Authorizations
Source: U.S. Food and Drug Administration (FDA). Published: 2/4/2020. This resource, updated on February 4, 2020, lists current and terminated Emergency Use Authorizations that make available diagnostic and therapeutic medical devices to diagnose and respond to public health emergencies. The topics covered include 2019 Novel Coronavirus Emergency Use Authorization; Zika Virus Emergency Use Authorization; 2015 Enterovirus D68 (EV-D68) Emergency Use Authorization; 2014 Ebola Virus Emergency Use Authorization; 2013 Coronavirus Emergency Use Authorization (Potential Emergency); 2013 H7N9 Influenza Emergency Use Authorization ...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 4, 2020 Category: International Medicine & Public Health Source Type: news

Enterovirus A71 Outbreak in Children ID'd in Colorado Hospital
WEDNESDAY, Jan. 15, 2020 -- In an observational cohort study recently published in The Lancet Infectious Diseases, details are presented for an outbreak of enterovirus A71 (EV-A71) neurological disease in children who presented to a Colorado... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 15, 2020 Category: Pharmaceuticals Source Type: news

Children's Hospital Colorado uncovers largest US outbreak of neurologic disease to date
(Children's Hospital Colorado) The Lancet Infectious Diseases recently published the results of an observational study conducted by researchers at Children's Hospital Colorado that led to a discovery of the largest outbreak of enterovirus A71 (EV-A71) in the United States. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news

2019 Research Highlights — Basic Research Insights
Noteworthy NIH advances in basic research include evidence linking enterovirus infections with acute flaccid myelitis, insights into how disrupted sleep may lead to heart disease, and nanoparticle robots that sweep away biofilms. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 17, 2019 Category: Consumer Health News Source Type: news

Host cell proteases can process viral capsid proteins
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) It has long been suggested that a cell protease could take part in enterovirus infection. However, the identity of such proteases have remained unknown. The work performed in the University of Jyv ä skyl ä shows, for the first time, that host cell calpain proteases can process enterovirus polyprotein in vitro. The research was published in Viruses scientific journal in November 2019. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 4, 2019 Category: Infectious Diseases Source Type: news

Unexpected viral behavior linked to type 1 diabetes in high-risk children
(University of South Florida (USF Health)) New results from the Environmental Determinants of Diabetes in the Young (TEDDY) study show an association between prolonged enterovirus infection and development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes. Conversely, adenovirus C infection seems to confer protection from autoimmunity. The international research suggests new therapeutic avenues for prevention in some children. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 2, 2019 Category: Infectious Diseases Source Type: news

Molecular and Clinical Comparison of EV-D68 Outbreaks Molecular and Clinical Comparison of EV-D68 Outbreaks
A new study compares the molecular characteristics and clinical manifestations from two enterovirus D68 outbreak periods. What have we learned?Emerging Infectious Diseases (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - November 27, 2019 Category: Infectious Diseases Tags: Public Health & Prevention Journal Article Source Type: news

Cellular calpain proteases can cleave the enteroviral polyprotein
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) Enteroviruses can cause severe diseases such as encephalitis or myocarditis, and have been associated with chronic diseases such as type 1 diabetes. In her dissertation at the University of Jyvaskyla M.Sc Mira Laajala focuses on viral and host cell factors that promote the infection of enterovirus B species after cell entry. The research showed that in addition to enteroviral proteases, cellular calpain proteases can cleave the enteroviral polyprotein. The information may possibly be used in antiviral development. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2019 Category: International Medicine & Public Health Source Type: news

More Evidence that Enterovirus May Cause Kids' Paralyzing Disease
Children with acute flaccid myelitis are more likely to have antibodies against the viral family in their spinal fluid than are children without the illness. (Source: The Scientist)
Source: The Scientist - October 22, 2019 Category: Science Tags: News & Opinion Source Type: news

Enterovirus Implicated in Acute Flaccid Myelitis Enterovirus Implicated in Acute Flaccid Myelitis
Enterovirus is the likely cause of pediatric acute flaccid myelitis, new research suggests. A vaccine against two main suspects could become key in preventing the devastating disorder, experts note.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 22, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Scientists admit they have no idea how newly discovered enterovirus infects hosts
Researchers at Tokyo University of Agriculture and Technology (TUAT) said we may be facing an 'new system of viral evolution'. The virus doesn't have the same structure as other viruses. (Source: the Mail online | Health)
Source: the Mail online | Health - October 22, 2019 Category: Consumer Health News Source Type: news

Signs of Virus Seen in Disease Paralyzing Kids
The new test detected antibodies for two types of enteroviruses in the spinal fluid of dozens of patients diagnosed with acute flaccid myelitis (AFM), a disease that causes potentially permanent and sometimes life-threatening paralysis in young children. (Source: WebMD Health)
Source: WebMD Health - October 21, 2019 Category: Consumer Health News Source Type: news

Antiviral Antibodies ID'd in CSF of Acute Flaccid Myelitis Cases
MONDAY, Oct. 21, 2019 -- Enterovirus (EV)-specific antibodies have been identified in the cerebrospinal fluid (CSF) of pediatric cases of acute flaccid myelitis (AFM) versus controls, according to a study published online Oct. 21 in Nature... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 21, 2019 Category: Pharmaceuticals Source Type: news

'Powerful piece of circumstantial evidence' that virus causes paralyzing illness in kids
Study provides the most robust evidence so far that enteroviruses cause AFM, a mysterious illness that can start like the sniffles but quickly paralyze children. (Source: CBC | Health)
Source: CBC | Health - October 21, 2019 Category: Consumer Health News Tags: News/Health Source Type: news