Impact of Ebola and COVID-19 on maternal, neonatal, and child health care among populations affected by conflicts: a scoping review exploring demand and supply-side barriers and solutions
Armed conflicts have a severe impact on the health of women and children. Global health emergencies such as pandemics and disease outbreaks further exacerbate the challenges faced by vulnerable populations in ... (Source: Conflict and Health)
Source: Conflict and Health - January 30, 2024 Category: International Medicine & Public Health Authors: Yasir Shafiq, Elena Rubini, Zoha Zahid Fazal, Muhammad Murtaza Bukhari, Maheen Zakaria, Noor ul Huda Zeeshan, Ameer Muhammad, Luca Ragazzoni, Francesco Barone-Adesi and Martina Valente Tags: Review Source Type: research
‘It’s insane’: New viruslike entities found in human gut microbes
As they collect and analyze massive amounts of genetic sequences from plants, animals, and microbes, biologists keep encountering surprises, including some that may challenge the very definition of life. The latest, reported this week in a preprint, is a new kind of viruslike entity that inhabits bacteria dwelling in the human mouth and gut. These “obelisks,” as they’re called by the Stanford University team that unearthed them, have genomes seemingly composed of loops of RNA and sequences belonging to them have been found around the world.
Other scientists are delighted by obelisks’ debut. “It’s insane,...
Source: Science of Aging Knowledge Environment - January 26, 2024 Category: Geriatrics Source Type: research
News at a glance: Long-awaited malaria shots, risks of face recognition technology, and Japan ’s first moon landing
GLOBAL HEALTH
Long-awaited malaria shots rolled out
After a 60-year quest, the first-ever routine childhood malaria vaccinations—those given as part of the regular immunization schedule—were administered to infants and toddlers in Cameroon on 22 January. They received RTS,S or Mosquirix, made by GlaxoSmithKline and approved for general use in 2021 by the World Health Organization (WHO). The vaccine’s efficacy wanes substantially over time, but a 4-year pilot rollout required by WHO in Ghana, Kenya, and Malawi showed it slashed illness and death in young children. Nineteen other African countrie...
Source: Science of Aging Knowledge Environment - January 25, 2024 Category: Geriatrics Source Type: research
Building Research Capacity in Low- and Middle-Income Countries and Pandemic Preparedness: Lessons Learned and Future Directions
Am J Trop Med Hyg. 2024 Jan 23:tpmd230675. doi: 10.4269/ajtmh.23-0675. Online ahead of print.ABSTRACTResearch capacity is a critical component of pandemic preparedness, as highlighted by the challenges faced during the Ebola outbreak in West Africa. Recent global initiatives, such as the Research & Development Task Force of the Global Health Security Agenda and the World Health Assembly's resolution on strengthening clinical trials, emphasize the need for robust research capabilities. This Perspective discusses the experiences of leaders in infectious disease research and capacity building in low- and middle-income cou...
Source: Am J Trop Med Hyg - January 24, 2024 Category: Infectious Diseases Authors: Peter H Kilmarx Karen A Goraleski Erum Khan John F Lindo Nancy Gore Saravia Source Type: research
Building Research Capacity in Low- and Middle-Income Countries and Pandemic Preparedness: Lessons Learned and Future Directions
Am J Trop Med Hyg. 2024 Jan 23:tpmd230675. doi: 10.4269/ajtmh.23-0675. Online ahead of print.ABSTRACTResearch capacity is a critical component of pandemic preparedness, as highlighted by the challenges faced during the Ebola outbreak in West Africa. Recent global initiatives, such as the Research & Development Task Force of the Global Health Security Agenda and the World Health Assembly's resolution on strengthening clinical trials, emphasize the need for robust research capabilities. This Perspective discusses the experiences of leaders in infectious disease research and capacity building in low- and middle-income cou...
Source: The American Journal of Tropical Medicine and Hygiene - January 24, 2024 Category: Tropical Medicine Authors: Peter H Kilmarx Karen A Goraleski Erum Khan John F Lindo Nancy Gore Saravia Source Type: research
Prophylactic and therapeutic measures for emerging and re-emerging viruses: artificial intelligence and machine learning - the key to a promising future
ConclusionsThe present review not only highlighted public-health management models but also provide leads in potential therapeutic targets as well as vaccine/ antiviral candidates. To support the context, the issues with existing therapeutic strategies are also overviewed and the prospects were identified. This review discusses a wide range of applications of AI and ML pertaining to the clinical domain. (Source: Health and Technology)
Source: Health and Technology - January 24, 2024 Category: Information Technology Source Type: research
Preparing for another Ebola Outbreak: The impact of viral inactivation methods on commonly measured biochemistry analytes in plasma and urine
CONCLUSION: Reliable results for commonly measured electrolytes, enzymes and proteins can be obtained after viral inactivation by Triton X-100 treatment at room temperature. However, heat inactivation has significant negative impact on routine biochemistry enzymes and alternative testing processes should be explored.PMID:38242342 | DOI:10.1016/j.clinbiochem.2024.110718 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - January 19, 2024 Category: Biochemistry Authors: Janet Zhou Franceska Sevilleno Fari Rokhforooz Jennifer Taher Source Type: research
Impact of Ebola epidemics on the daily operation of existing systems in Eastern Democratic Republic of the Congo: a brief review
CONCLUSION: National leadership has not yet taken the lead in strategic, operational, or financial aspects. Therefore, national leaders should double their efforts and awareness to encourage local fundraising, sufficient budget al.location, infrastructure construction, equipment provision, and staff training, to effectively support a holistic approach in response to outbreaks, providing effective results, and all types of research activities.PMID:38240249 | DOI:10.1080/13696998.2024.2305009 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - January 19, 2024 Category: Health Management Authors: Daniel Mukadi-Bamuleka Antoine Nkuba-Ndaye Placide Mbala-Kingebeni Steve Ahuka-Mundeke Jean-Jacques Muyembe-Tamfum Source Type: research
Navigating the Complex Landscape of Ebola Infection Treatment: A Review of Emerging Pharmacological Approaches
AbstractIn 1976 Ebola revealed itself to the world, marking the beginning of a series of localized outbreaks. However, it was the Ebola outbreak that began in 2013 that incited fear and anxiety around the globe. Since then, our comprehension of the virus has been steadily expanding. Ebola virus (EBOV), belonging to theOrthoebolavirus genus of theFiloviridae family, possesses a non-segmented, negative single-stranded RNA genome comprising seven genes that encode multiple proteins. These proteins collectively orchestrate the intricate process of infecting host cells. It is not possible to view each protein as monofunctional....
Source: Infectious Diseases and Therapy - January 19, 2024 Category: Infectious Diseases Source Type: research
Introduction of high containment laboratories in abroad
Uirusu. 2022;72(2):139-148. doi: 10.2222/jsv.72.139.ABSTRACTRecently, outbreaks of highly pathogenic viruses, such as those of Ebola and Lassa viruses, have become a global public health issue. Such viruses must be handled in biosafety level 4 (BSL-4) laboratories. Currently, 62 BSL-4 laboratories are in operation, under construction, or planned in 24 counties. In this review, I provide an overview of the current status and characteristics of BSL-4 facilities in abroad and introduce my research on the wild-type Ebola virus at the BSL-4 facility in the USA.PMID:38220158 | DOI:10.2222/jsv.72.139 (Source: Uirusu. Journal of Virology)
Source: Uirusu. Journal of Virology - January 14, 2024 Category: Virology Authors: Wakako Furuyama Asuka Nanbo Source Type: research
Introduction of high containment laboratories in abroad
Uirusu. 2022;72(2):139-148. doi: 10.2222/jsv.72.139.ABSTRACTRecently, outbreaks of highly pathogenic viruses, such as those of Ebola and Lassa viruses, have become a global public health issue. Such viruses must be handled in biosafety level 4 (BSL-4) laboratories. Currently, 62 BSL-4 laboratories are in operation, under construction, or planned in 24 counties. In this review, I provide an overview of the current status and characteristics of BSL-4 facilities in abroad and introduce my research on the wild-type Ebola virus at the BSL-4 facility in the USA.PMID:38220158 | DOI:10.2222/jsv.72.139 (Source: Uirusu. Journal of Virology)
Source: Uirusu. Journal of Virology - January 14, 2024 Category: Virology Authors: Wakako Furuyama Asuka Nanbo Source Type: research
Introduction of high containment laboratories in abroad
Uirusu. 2022;72(2):139-148. doi: 10.2222/jsv.72.139.ABSTRACTRecently, outbreaks of highly pathogenic viruses, such as those of Ebola and Lassa viruses, have become a global public health issue. Such viruses must be handled in biosafety level 4 (BSL-4) laboratories. Currently, 62 BSL-4 laboratories are in operation, under construction, or planned in 24 counties. In this review, I provide an overview of the current status and characteristics of BSL-4 facilities in abroad and introduce my research on the wild-type Ebola virus at the BSL-4 facility in the USA.PMID:38220158 | DOI:10.2222/jsv.72.139 (Source: Uirusu. Journal of Virology)
Source: Uirusu. Journal of Virology - January 14, 2024 Category: Virology Authors: Wakako Furuyama Asuka Nanbo Source Type: research
Introduction of high containment laboratories in abroad
Uirusu. 2022;72(2):139-148. doi: 10.2222/jsv.72.139.ABSTRACTRecently, outbreaks of highly pathogenic viruses, such as those of Ebola and Lassa viruses, have become a global public health issue. Such viruses must be handled in biosafety level 4 (BSL-4) laboratories. Currently, 62 BSL-4 laboratories are in operation, under construction, or planned in 24 counties. In this review, I provide an overview of the current status and characteristics of BSL-4 facilities in abroad and introduce my research on the wild-type Ebola virus at the BSL-4 facility in the USA.PMID:38220158 | DOI:10.2222/jsv.72.139 (Source: Uirusu. Journal of Virology)
Source: Uirusu. Journal of Virology - January 14, 2024 Category: Virology Authors: Wakako Furuyama Asuka Nanbo Source Type: research
Introduction of high containment laboratories in abroad
Uirusu. 2022;72(2):139-148. doi: 10.2222/jsv.72.139.ABSTRACTRecently, outbreaks of highly pathogenic viruses, such as those of Ebola and Lassa viruses, have become a global public health issue. Such viruses must be handled in biosafety level 4 (BSL-4) laboratories. Currently, 62 BSL-4 laboratories are in operation, under construction, or planned in 24 counties. In this review, I provide an overview of the current status and characteristics of BSL-4 facilities in abroad and introduce my research on the wild-type Ebola virus at the BSL-4 facility in the USA.PMID:38220158 | DOI:10.2222/jsv.72.139 (Source: Uirusu. Journal of Virology)
Source: Uirusu. Journal of Virology - January 14, 2024 Category: Virology Authors: Wakako Furuyama Asuka Nanbo Source Type: research
