The dark side of DNA - how the immune system senses DNA as a danger signal
Zhijian “ James ” Chen ’ s research into complex cellular biochemistry has led to the discovery of pathways and proteins that trigger immune and stress responses. Chen has identified proteins, such as the mitochondrial protein MAVS, that are crucial to the body ’ s defense against RNA viruses such as influenza and Ebola. Now, Chen and his team are dissecting a signaling pathway involving a novel DNA sensor – cyclic GMP-AMP (cGAMP) synthase, or cGAS – which activates an interferon response that may play a role in immune defense against pathogens and malignant cells, as well as in autoimmune diseases such as lupu...
Source: Videocast - All Events - July 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Genomic Surveillance and Characterization of Microbial Threats Facilitates Early Detection and Containment of Disease Outbreaks in West Africa.
Dr. Christian Happy, has the expertise and skills, leadership and motivation necessary to successfully conduct and oversee health research projects in West Africa. He has a broad background in molecular biology and genomics with application in infectious diseases, including malaria, Lassa fever, Ebola virus disease and HIV. Of his career accomplishments to date, the most meaningful was my use of genomics technologies for early diagnosis and confirmation (within 6 hours) of Ebola virus disease (EVD) in Nigeria. This singular action was major in containing EVD in Nigeria, and therefore saving millions of lives in Africa. Thi...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
COVID-19, International Law, and Data Governance
Speaker Alexandra L. Phelan is an Adjunct Professor in Global and Public Health Law and Ethics, Doctor of Juridical Science (SJD) candidate and General Sir John Monash Scholar at Georgetown University in Washington DC. Professor Phelan ’ s doctoral research examines the global governance of infectious diseases, with a focus on Australian, Chinese and US laws relating to the health and human rights of vulnerable population groups. Professor Phelan ’ s research explores the key legal issues of emerging and re-emerging infectious diseases – such as Ebola, Pandemic Influenza, MERS, and Zika Virus – in the face of press...
Source: Videocast - All Events - September 21, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Evolutionary Dynamics of SARS-CoV-2
This is the annual Dewitt Stetten Jr. Lecture. Speaker Trevor Bedford, Ph.D., is Associate Professor, Vaccine and Infectious Disease Division; Associate Professor, Herbold Computational Biology Program; and Associate Professor, Human Biology Division, Fred Hutch. Bedford uses powerful computers and complex statistical methods to study the rapid spread and evolution of viruses, including those that cause COVID-19, influenza, Ebola and Zika. Data gathered from these processes help researchers develop successful strategies for monitoring and controlling infectious diseases.For more information go tohttps://oir.nih.gov/walsAir...
Source: Videocast - All Events - September 8, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
The RECOVERY Trial: Science in a Crisis
The speaker returned to Oxford in 2014 and established the Epidemic disease Research Group Oxford (ERGO). ERGO is engaged in an international program of clinical and epidemiological research to prepare for and respond to emerging infections that may develop into epidemics or pandemics. ERGO is involved in a number of international projects including the European Commission funded PREPARE project, and ISARIC (International Severe Acute Respiratory and Emerging Infection Consortium). The group is conducting research on a range of epidemic diseases including Ebola virus disease, bird flu (H5N1 and H7N9), MERS-CoV, and Enterov...
Source: Videocast - All Events - December 10, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Clinical Trials in Public Health Emergencies: the Ebola and COVID Experiences
NIH COVID-19 SIG Lecture Series
Designing and implementing clinical trials for novel infectious disease treatments brings many challenges, especially during a rapidly evolving pandemic. A new disease brings uncertainties arising from an imperfect understanding about illness, limited information about proposed countermeasures, and complexities in measuring relevant patient outcomes. A pandemic adds an overloaded medical system with limited resources for research, heightened pressure to find cures quickly, and unpredictability about potential case numbers. I will discuss issues related to designing and conducting treatment t...
Source: Videocast - All Events - May 11, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
The Biomedical Research Response to COVID-19: A View from NIAID
NIH COVID-19 SIG Lecture Series
NIAID has a long-standing dual mandate to maintain a robust portfolio of research in its key focus areas and to respond to emerging and re-emerging infectious diseases (EIDs). With this mandate, NIAID has also sought to improve EID-response preparedness, working in partnership with other U.S. government research entities, industry, academia, and international public-health organizations. This preparedness planning helped the institute respond rapidly to COVID-19. NIAID tapped existing coronavirus expertise and other assets to stand up research programs spanning basic virology and immunology ...
Source: Videocast - All Events - April 13, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Rear Admiral (Upper Half) Richard W. Childs Flag Promotion Ceremony
The United States Public Health Service Flag Promotion ceremony for Rear Admiral (RADM) Richard W. Childs, promoted to RADM Upper Half O-8 in January 2020, is being webcast live on 3/27/2020 from Masur Auditorium. Richard Childs, MD serves as the Clinical Director of the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (NIH). He was commissioned in the USPHS Commissioned Corps as a Lieutenant in 1995 when joined the NCI as an Oncology Fellow. Following fellowship training, he was appointed a tenure-track investigator in the Hematology Branch of the NHLBI where he continues to conduct r...
Source: Videocast - All Events - February 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
CANCELLED - Demystifying Medicine - 1) The Challenge of Pandemic Preparedness 2) Current Status of Emerging and Re-emerging Infectious Diseases
Demystifying Medicine Lecture Series
Ebola, swine flu, drug-resistant tuberculosis, diarrheal diseases, and just about anything carried by mosquitoes … These are but a few of the infectious diseases that keep Drs. Fauci and Glass awake at night. Oh, and ticks, too. Threats are everywhere.
Every day, it seems, brings outbreaks and the potential for a pandemic. And yet, remarkably, scientists and healthcare providers on the frontlines manage to keep billions of people relatively safe. This Demystifying Medicine lecture by two of the biggest names in global health will provide a broad perspective on the myriad infectious d...
Source: Videocast - All Events - January 7, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Demystifying Medicine - Ebola: Then, Now and the NIH
The Demystifying Medicine Lecture Series is designed to help bridge the gap between advances in biology and their applications to major human diseases. The lectures include presentations of patients, pathology, diagnosis, and therapy in the context of major diseases and current research. All clinicians, trainees including fellows, medical students, Ph.D. students, and other healthcare and research professionals are welcome to attend.For more information go tohttps://demystifyingmedicine.od.nih.govAir date: 1/14/2020 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 3, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Demystifying Medicine - 1) The Challenge of Pandemic Preparedness 2) Current Status of Emerging and Re-emerging Infectious Diseases
Demystifying Medicine Lecture Series
Ebola, swine flu, drug-resistant tuberculosis, diarrheal diseases, and just about anything carried by mosquitoes … These are but a few of the infectious diseases that keep Drs. Fauci and Glass awake at night. Oh, and ticks, too. Threats are everywhere.
Every day, it seems, brings outbreaks and the potential for a pandemic. And yet, remarkably, scientists and healthcare providers on the frontlines manage to keep billions of people relatively safe. This Demystifying Medicine lecture by two of the biggest names in global health will provide a broad perspective on the myriad infectious d...
Source: Videocast - All Events - January 3, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Demystifying Medicine: Ebola: Then, Now and the NIH
The Demystifying Medicine Lecture Series is designed to help bridge the gap between advances in biology and their applications to major human diseases. The lectures include presentations of patients, pathology, diagnosis, and therapy in the context of major diseases and current research. All clinicians, trainees including fellows, medical students, Ph.D. students, and other healthcare and research professionals are welcome to attend.For more information go tohttps://demystifyingmedicine.od.nih.govAir date: 1/14/2020 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: Clinicopathologic Grand Rounds: Clinical Cases from the NIH: Clinical Center Ebola Virus: An Update on Ecology and Molecular Correlates of Critical Illness
CC Grand Rounds: Clinicopathologic Grand Rounds: Clinical Cases from the NIH: Clinical Center Ebola Virus: An Update on Ecology and Molecular Correlates of Critical IllnessFor more information go tohttps://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 5/29/2019 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 29, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: Response to an Outbreak: Ebola Virus Monoclonal Antibody (mAb114) Rapid Clinical Development
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 3/13/2019 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: Contemporary Clinical Medicine: Great Teachers Response to an Outbreak: Ebola Virus Monoclonal Antibody (mAb114) Rapid Clinical Development
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 3/13/2019 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
