TWiV 961: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals, sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody for breakthrough infections during the epidemic of the Omicron variants, effect of wearing glasses on risk...
Source: This Week in Virology - MP3 Edition - December 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 955: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations, acute and postacute sequelae associated with SARS-CoV-2 reinfection, clinical course of SARS-CoV-2 infection and recovery in lung transplant recipients, effectiveness of a third BNT162b2 mRNA COVID-19 vaccina...
Source: This Week in Virology - MP3 Edition - November 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 931: Driven to immunodistraction
TWiV reviews the genetic characterization of a new strain of type 2 oral polio vaccine and its implications for eradication, and how a polymorphism in humans comprising a single amino acid change in an antibody molecule regulates vaccine elicitation of broadly neutralizing antibodies against influenza virus HA. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Characterization of novel OPV2 from humans (MMWR) Engineering nOPV2 (TWiV 756) Genome sequence of Rockland...
Source: This Week in Virology - MP3 Edition - August 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 891: LLOV in the time of Ebola
Elke, Adam, and Gabor join TWiV to discuss their work on Lloviu virus, a filovirus, including recovery of infectious virus from a DNA copy of the genome and from Schreiber’s bats in Hungary. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guests: Elke Muhlberger, Adam Hume, and Gabor Kemenesi Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Elke on TWiV 200 and Threading the NEIDL Infectious Lloviu virus from bats in Hungary (Nat Commun) Infectious Lloviu virus from DNA (PloS Path) Letters read on TWiV 891 Timestamps by Jolene...
Source: This Week in Virology - MP3 Edition - April 21, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 871: If the ACE2 fits, ferret
TWiV discusses whether or not Omicron should be designated a new serotype of SARS-CoV-2, and the finding that amino acid changes that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ABRCMS ePoster Spring Symposium for Emerging Scientists ASV Annual Meeting Registration (ASV) Microbiology & Immunology at LSU Health Is Omicron a new serotype? (Nat Rev Micr) Adaptation of SARS-CoV-2 to mink/ferret (Cell Rep) Letters read on T...
Source: This Week in Virology - MP3 Edition - February 27, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 854: Omicron is evasive
TWiV reviews findings that increased fitness of the Omicron variant is due to immune evasion, not an increase in intrinsic transmissibility, and determination of infectious viral load in patients infected with wild type, Delta and Omicron viruses reveals lack of correlation with RNA loads determined by RT-PCR, similar levels of shedding among Delta and Omicron, and greatly reduced shedding in vaccinated people. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Travel Awa...
Source: This Week in Virology - MP3 Edition - January 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: COVID's origins and the 'lab leak' theory
Where did the SARS-CoV-2 virus come from? As a team of researchers from the WHO prepares to report on its investigation into the origins of the virus, we discuss the leading theories, including the controversial ‘lab leak' hypothesis.Although there is no evidence to support it, the lab-leak idea remains popular among certain groups. Similar hypotheses were even touted about the Ebola outbreak in Sierra Leone. We discuss why theories like this seem to gain traction.News: ‘Major stones unturned’: COVID origin search must continue after WHO report, say scientistsNews: Where did COVID come from? Five myste...
Source: Nature Podcast - March 5, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: COVID's origins and the'lab leak' theory
Where did the SARS-CoV-2 virus come from? As a team of researchers from the WHO prepares to report on its investigation into the origins of the virus, we discuss the leading theories, including the controversial ‘lab leak' hypothesis.Although there is no evidence to support it, the lab-leak idea remains popular among certain groups. Similar hypotheses were even touted about the Ebola outbreak in Sierra Leone. We discuss why theories like this seem to gain traction.News: ‘Major stones unturned’: COVID origin search must continue after WHO report, say scientistsNews: Where did COVID come from? Five myste...
Source: Nature Podcast - March 5, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronavirus Update With Peter Piot, MD, PhD
Peter Piot, MD, PhD, director of The London School of Hygiene and Tropical Medicine, is a legend in global health, having been involved in identification of HIV and Ebola virus in Africa. He was founding executive director of UNAIDS and Under Secretary-General of the United Nations from 1995 to 2008. He joins JAMA's Q&A series to discuss the global public health response to COVID-19 past, present, and future. Recorded January 28, 2021. Related Article(s): The Challenges Ahead With Monoclonal Antibodies (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - February 1, 2021 Category: General Medicine Authors: JAMA Network Source Type: podcasts

The BMJ interview: Fixing America’s covid response in the Biden era
US president elect Joe Biden wasted no time in appointing a special advisory board of experts to guide America out of its coronavirus crisis. One of those experts is Celine Gounder, an infectious diseases epidemiologist who has worked on Ebola, tuberculosis, and HIV in Africa and South America. She’s a clinical assistant professor of medicine and infectious diseases at New York University’s School of Medicine, as well as an active w riter and podcast host, including of Epidemic In this podcast she talks to Joanne Silberner about the ways in which the taskforce is helping prepare for action immediately after the inau...
Source: The BMJ Podcast - January 19, 2021 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

The BMJ interview: Fixing America ’s covid response in the Biden era
US president elect Joe Biden wasted no time in appointing a special advisory board of experts to guide America out of its coronavirus crisis. One of those experts is Celine Gounder, an infectious diseases epidemiologist who has worked on Ebola, tuberculosis, and HIV in Africa and South America. She’s a clinical assistant professor of medicine and infectious diseases at New York University’s School of Medicine, as well as an active writer and podcast host, including of Epidemic In this podcast she talks to Joanne Silberner about the ways in which the taskforce is helping prepare for action immediately after the inaug...
Source: The BMJ Podcast - January 19, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: Lessons from pandemic ‘war-game’ simulations
Next week, we’ll be wrapping up Coronapod in its current form. Please fill out our short survey to let us know your thoughts on the show.In this episode:02:15 Simulating pandemicsResearchers have run numerous military-style simulations to predict the consequences of fictitious viral outbreaks. We discuss how these simulations work, what recommendations come out of them and if any of these warnings have been heeded.24:08 One good thingOur hosts pick out things that have made them smile in the last week, including audience feedback, the official end of the Ebola outbreak in the northeastern Democratic Republic of the Congo...
Source: Nature Podcast - July 3, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: Lessons from pandemic ‘war-game’ simulations
Next week, we’ll be wrapping up Coronapod in its current form. Please fill out our short survey to let us know your thoughts on the show.In this episode:02:15 Simulating pandemicsResearchers have run numerous military-style simulations to predict the consequences of fictitious viral outbreaks. We discuss how these simulations work, what recommendations come out of them and if any of these warnings have been heeded.24:08 One good thingOur hosts pick out things that have made them smile in the last week, including audience feedback, the official end of the Ebola outbreak in the northeastern Democratic Republic of the Congo...
Source: Nature Podcast - July 3, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: Dexamethasone, the cheap steroid that could cut coronavirus deaths
In this episode:00:37 Lessons from the Ebola outbreakWe get an update on the pandemic response in the African countries still reeling from the 2014 Ebola crisis. Resource strapped and under pressure – can the lessons learned from Ebola help keep the coronavirus under control?15:32 Dexamethasone, a breakthrough drug?A UK-based drugs trial suggests that a cheap steroid could cut deaths by a third among the sickest COVID patients. We discuss what this could mean for the pandemic.News: Coronavirus breakthrough: dexamethasone is first drug shown to save lives20:06 One good thingOur hosts pick out things that have made th...
Source: Nature Podcast - June 19, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts