Can Digital Technologies Help Overcome Diabetes? An Assessment of the Recent PHTI Review
Payers are always wary about funding new treatments for illnesses and conditions: When millions of dollars are at stake, payers want demonstrated improvements in outcomes. So do doctors and patients, before they go through the trouble of adopting a course of treatment. So there was much consternation recently when the Peterson Health Technology Institute (PHTI) released a report saying that digital interventions weren’t helping people with diabetes much and weren’t worth their added costs. PHTI has a comprehensive and detailed assessment framework that it applies to health care technologies to determine whether...
Source: EMR and HIPAA - April 8, 2024 Category: Information Technology Authors: Andy Oram Tags: Clinical Health IT Company Healthcare IT Telemedicine and Remote Monitoring A1c ANdy Molnar Behavior Change Behavior Health CGM Continuous Glucose Monitoring Dario Health diabetes Diabetes Monitoring Digital Health Digital Ther Source Type: blogs

Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls. Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

This Simple Technique Can Double Weight Loss Results
This weight loss is achieved without making changes to exercise or diet. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 6, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Weight Loss Source Type: blogs

How to control high blood pressure without medications
Just because you have been told that your blood pressure is above normal need not mean that you are tied up to medications lifelong. Changes in lifestyle can definitely bring down your blood pressure even without medications. In those already taking medications, the dose of medications can be brought down by important lifestyle changes. Some lucky ones may be able to stop medications as well. But you have to continue monitoring your blood pressure regularly so that any recurrence can be picked up. One of the important ways in which to reduce elevated blood pressure is by reducing extra weight. Roughly the blood pressure mi...
Source: Cardiophile MD - April 6, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

An Urgent Call to Raise Awareness of Heart Disease in Women
By KELLY CARROLL There is a dire need to raise awareness about heart disease in women. It is the number one killer of American women, and key data points reveal a lack of cognizance among doctors and women. An assessment of primary care physicians published in 2019 revealed that only 22% felt extremely well prepared to evaluate cardiovascular disease risks in female patients. A 2019 survey of American women showed that just 44% recognized heart disease as the number one cause of death in women. Ten years earlier, in 2009, the same survey found that 65% of American women recognized heart disease as the leading cause o...
Source: The Health Care Blog - April 5, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice heart disease Kelly Carroll Life Essential 8 prevention Womens health Source Type: blogs

A View of Type 2 Diabetes as Accelerated Aging
The mortality characteristics resulting from type 2 diabetes look very much like an accelerated form of normal aging, as noted in today's open access paper reporting on a large epidemiological study. This mortality characteristic is so much like aging that at times in the past researchers have used animal models of type 2 diabetes as stand-ins for aging, in order to conduct studies more rapidly. Type 2 diabetes is a metabolic disease, a condition that usually arises from excess fat tissue, and is characterized by chronic inflammation, excessive blood sugar, high levels of circulating advanced glycation end-products, and ot...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes. « Back to Top A Skeptical View of the Role of Nuclear DNA Damage in Aging https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/ It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Advantages, Challenges, and Costs of Healthcare at Home Services
Switching to fully remote operations during the pandemic was a rushed adventure into what was mostly uncharted territory. There were a lot of challenges and bugs to work out, but there were also plenty of advantages and unforeseen benefits. And it is thanks to those advantages and benefits that healthcare at home is continuing, even as there are still challenges to work on and in-person operations return. While our first big push into remote care was a leap into the unknown, this time we want to make sure that we are surveying the landscape to make this a safe, smart, and financially responsible decision. So let’s ta...
Source: EMR and HIPAA - March 28, 2024 Category: Information Technology Authors: Grayson Miller Tags: Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Revenue Cycle Management Telemedicine and Remote Monitoring Alaina Victoria Ash Wellness Brenden Hayden Carenet Health Carium Chris Darland David McCormick Source Type: blogs

Interesting Epidemiological Results for Time Restricted Feeding
In this study, researchers investigated the potential long-term health impact of following an 8-hour time-restricted eating plan. They reviewed information about dietary patterns for participants in the annual 2003-2018 National Health and Nutrition Examination Surveys (NHANES) in comparison to data about people who died in the U.S., from 2003 through December 2019, from the Centers for Disease Control and Prevention's National Death Index database. The analysis found: (a) people who followed a pattern of eating all of their food across less than 8 hours per day had a 91% higher risk of death due to cardiovascular d...
Source: Fight Aging! - March 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Apigenin, Sleep, and Aging
For those following research into efforts to upregulate NAD+ levels to improve mitochondrial function, this paper is an interesting sidebar. Some degree of loss of NAD+ emerges from increased activity of CD38. Apigenin is a dietary supplement that can modestly influence both sleep and pace of aging, the latter in short-lived laboratory species at least. Apigenin can increase NAD+ levels by inhibiting CD38 activity. Like much of metabolism, this is all very interesting, but the effect sizes are nothing to write home about. If upregulating NAD+ levels is the goal, you'll do better by exercising. The fundamental flaw in so mu...
Source: Fight Aging! - March 26, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Predicting the Order of Arrival of the First Rejuvenation Therapies
It has been going on eight years since I last speculated on the order of arrival of the first rejuvenation therapies. Tempus fugit, and time for an updated version! Eight years is a long enough span of time for the first of those rejuvenation therapies to now exist, albeit in a prototypical form, arguably proven in principle but not concretely. The world progresses but my biases remain much the same: the first rejuvenation therapies to work well enough to merit the name will be based on the SENS vision, that aging is at root caused by a few classes of accumulated cell and tissue damage, and biotechnologies that either repa...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Redi Health Lands $14 Million Investment to Continue Improving Patient Health Outcomes by Connecting Pharma, Providers, and Patients in One Platform
Series B Funding Round Led by Blue Heron Capital, with Participation from North Coast Ventures, Refinery Ventures, Mutual Capital Partners, Rev1 Ventures, and M25 Redi Health today announced that it has closed $14 million in Series B funding. The funding round was led by Blue Heron Capital, with participation from North Coast Ventures and existing investors Refinery Ventures, Mutual Capital Partners, Rev1 Ventures, and M25. Redi Health will use the financing to foster innovation, develop and launch new products, expand its unique network, and accelerate overall growth. The funding underscores Redi Health’s success...
Source: EMR and HIPAA - March 25, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Blue Heron Capital Gordon Crenshaw Health IT Funding Health IT Fundings Health IT Investment Jim Clair Luke Buchanan M25 Mutual Capital Partners North Coast Ventures Redi.Health Refinery Ventures Source Type: blogs

Thoughts on Micronutrient Intake During Calorie Restriction
Despite the considerable attention given to calorie restriction and intermittent fasting in the research community, there is very little formalism applied to the practice in humans. The few clinical trials conducted to date have had to pick their own protocols, and it is only comparatively recently that the fasting mimicking diet was developed to plant a flag on one specific implementation. The challenge here is that it is difficult to monetize calorie restriction and fasting, and thus there is no push towards standardization or more detailed assessment of variant protocols from any of the usual parties who might otherwise...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology. « Back to Top Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Weight Loss Diet That Cuts Belly Fat
The diet helps people control their blood sugar more effectively. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 21, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Weight Loss Source Type: blogs