Inflammaging in the Inner Ear, a Path to Hearing Loss
Inflammaging is a blanket term for the inappropriate inflammatory reaction of the immune system to the accumulation of molecular damage and other changes that take place with age. Constant, low-grade, unresolved inflammatory activation of the immune system is a feature of aging. It alters cell behavior for the worse and is disruptive to tissue structure and function. A number of different mechanisms contribute to forming and maintaining the state of inflammaging, such as pro-inflammatory signaling produced by ever-larger numbers of senescent cells, and innate immune recognition of mislocalized mitochondrial DNA that result...
Source: Fight Aging! - December 20, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Building a Culture of Safety in Perinatal Nursing: Insights from The Nurse Keith Show with Guest Jeanette Zocco
This special episode of The Nurse Keith Show titled " Perinatal Safety Nursing, Evidence-Based Practice, and Fostering a Culture of Safety, " features guest Jeanette Zocco, a perinatal quality and safety specialist. Zocco ' s experience and passion for perinatal nursing shine through as she discusses the critical importance of safety in nursing.Jeanette Zocco delves into the significance of safety protocols in perinatal nursing. She addresses the necessity of ingraining safety measures into everyday operations and embracing programs such as team steps and crew resource management. The dedication to fostering a safet...
Source: Digital Doorway - December 20, 2023 Category: Nursing Source Type: blogs

Ginger Vieira – Exercise with Type 1 Diabetes
In conclusion, Ginger Vieira’s book, Exercise with Type 1 Diabetes (affiliate link), is a must-read for anyone with diabetes who wants to incorporate exercise into their daily routine. Ginger’s expertise and personal experiences make this book a valuable resource for understanding the impact of exercise on blood sugar levels and managing diabetes effectively. With practical tips and a supportive approach, Ginger empowers readers to take control of their health and enjoy the benefits of exercise. Don’t miss out on this concise and informative guide! ...
Source: Scott's Diabetes Blog - December 20, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

5 Things We Learnt About Investments In Digital Health: Our E-book
At The Medical Futurist (TMF), and especially at The Medical Futurist Institute, we don’t usually deal with investment-related news and announcements. We receive many press releases coming from incubators and venture capital firms each week, but we never share them on our channels. Even though we focus on technologies and trends rather than companies of interest to investors, this doesn’t mean that we don’t keep a close eye on all these developments.  We are in close contact with many digital health startup founders, analyze the technologies they work on and objectively share news relevant to investors. A...
Source: The Medical Futurist - December 19, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Biotechnology Health Sensors & Trackers MySugr theranos invest portable diagnostics Gary rule Kardia CliniCloud tmfi alivecor MagicLeap covid19 digital health investors pandemic ecg R Source Type: blogs

Concerning EKG with a Non-obstructive angiogram. What happened?
CONCLUSION: Given resolution of severe CP in association with the above marked improvement of ST-T wave abnormalities in virtually all leads during the less than 1 hour between the recording of ECGs #1 and #2 — this strongly suggests reopening of a " culprit " vessel (whichever vessel this was)  — regardless of the fact that " no obstructive lesion was seen " at the time the cardiac catheterization happened to be done.The more than doubling of Troponin (even though " normal limits " for Troponin were not surpassed) — is consistent with a brief OMI, with only...
Source: Dr. Smith's ECG Blog - December 19, 2023 Category: Cardiology Authors: Willy Frick Source Type: blogs

Vida Health Announces $28.5 Million in Funding; Appoints Joe Murad CEO
Investment to Support Key Growth Initiatives and Drive Continued Focus on Improving Access to Effective, Affordable, and Sustainable Cardiometabolic Care Treatments Vida Health today announced it has closed $28.5 million in financing led by existing investors, including General Atlantic, Ally Bridge, Canvas Ventures, Hercules Capital, and other insiders. The company also named Joe Murad as Chief Executive Officer. Murad brings more than two decades of experience leading healthcare technology companies, with a demonstrated ability to guide venture-backed businesses from early stages through phases of significant growth. Mur...
Source: EMR and HIPAA - December 18, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Ally Bridge Canvas Ventures General Atlantic Health IT Funding Health IT Fundings Health IT Investment Hercules Capital Joe Murad Stephanie Tilenius Vida Health Source Type: blogs

Ozempic: miracle drug or a band-aid for obesity?
An excerpt from Dr. T’s Drop the Fat Diet: 12 Steps to Leaner You Forever. Semaglutide, a medication often marketed as Ozempic, Wegovy, or Rybelsus, has gained immense popularity in recent years. This is especially true in an age where diabetes and obesity are on the rise. The medication is being seen as a panacea Read more… Ozempic: miracle drug or a band-aid for obesity? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 16, 2023 Category: General Medicine Authors: Tags: Meds Obesity Source Type: blogs

CLEAR Trial of Bempedoic Acid
Bempedoic acid is an ATP citrate lyase inhibitor, acting upstream of HMGCoA reductase targeted by statins, and reduces LDL cholesterol levels. It is associated with low incidence of muscle related adverse events compared to statins. US FDA had a prerequisite that patients should be already on maximally tolerated stating therapy before considering bempedoic acid and had noted that their effect on cardiovascular morbidity and mortality were considered as indeterminate. The manufacturers have reported that these clauses have been removed. The CLEAR (Cholesterol Lowering via Bempedoic Acid [ECT1002], an ACL-Inhibiting Regime...
Source: Cardiophile MD - December 16, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Lifestyle matters: What we can do in 2024 to optimize cognition and life, delaying cognitive problems even dementia
This article was originally published on The Conversation. News in Context: Solving the Brain Fitness Puzzle Is the Key to Self-Empowered Aging What are cognitive abilities and how to boost them? The post Lifestyle matters: What we can do in 2024 to optimize cognition and life, delaying cognitive problems even dementia appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - December 14, 2023 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Alzheimer’s biological Brain-Fitness cognition cognitive engagement cognitive-abilities cognitive-reserve dementia depression exercise inflammation lifestyle neuroplasticity optimize cognition Stress Source Type: blogs

Top 6 Medical Trends To Watch for 2024
This study also reported a weight reduction of 4.0 kilograms and a 10.8-millimeter reduction in systolic blood pressure among patients. This segment is becoming significant in market terms as well: the market for DTx was valued at USD 5.53 billion in 2022 and is expected to grow to USD 28.66 billion by 2030. The increased prevalence of chronic conditions, as the result of our longer lives, fuels this growth as conditions like diabetes or hypertension can be more efficiently managed with a combination of traditional medicine and DTx.  While these apps are available in a large number of medical specialties, channe...
Source: The Medical Futurist - December 14, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Source Type: blogs

Abbott Gets Real About " Formulary Exclusions " Bankrolled by Rival Dexcom in the U.S.
My followers may recall that I ' ve written not-so-kind blog posts about how Dexcom paying legally-exempted rebate kickbacks (seehttps://blog.sstrumello.com/2023/06/dexcom-pays-pbms-kickbacks-to-exclude.html for one such blog post) to major Pharmacy Benefit Managers (PBMs) contingent upon " formulary exclusions of less costly rival continuous glucose monitoring (CGM) systems such as Abbott Freestyle Libre. The retail prices for both CGM sensor brands are remarkably close (ranging from $57.33/sensor to $61.28/sensor). However, the cost computation is not based on the cost per sensor, but must be computed on a cost per ...
Source: Scott's Web Log - December 14, 2023 Category: Endocrinology Tags: 2023 Abbott Freestyle Libre 3 coupons Dexcom PBM PBMs Source Type: blogs

Science Snippet: Zooming In on Nanoparticles
Nanoparticles come in many different shapes and configurations. Credit: Adapted from Stevens, et. al., under Creative Commons License 4.0. Nanoparticles may sound like gadgets from a science fiction movie, but they exist in real life. They’re particles of any material that are less than 100 nanometers (one-billionth of a meter) in all dimensions. Nanoparticles appear in nature, and humans have, mostly unknowingly, used them since ancient times. For example, hair dyeing in ancient Egypt involved lead sulfite nanoparticles, and artisans in the Middle Ages added gold and silver nanoparticles to stained-glass windows. Over...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 13, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Tools and Techniques Cool Tools/Techniques Cool Videos Medicines Science Snippet Source Type: blogs

Fight Aging! Newsletter, December 11th 2023
In this study, a single treatment at the peak of disease resulted in the ablation of senescent cells in the lung and attenuation of key fibrotic and inflammatory markers, which ultimately resolved fibrosis. Deciduous Therapeutics has used computational assisted design to synthesise a suite of proprietary therapies that could be used in the clinic to re-activate tissue-resident iNKT cells. To date, the company's lead program has shown single-dose efficacy in resolving both metabolic and fibrotic diseases along with a favorable safety profile at doses significantly higher than the efficacious dose. « Back to ...
Source: Fight Aging! - December 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mari Ruddy and Extreme Healing
Today, I have the pleasure of sharing an incredibly inspiring conversation with one of my heroes, Mari Ruddy. If you are not familiar with Mari, buckle up – her story is one of profound resilience, strength, and healing. Like me, Mari lives with type 1 diabetes. She was diagnosed in 1981, and in addition to dealing with diabetes, Mari has also courageously overcome several other life challenges. Mari discovered her love for distance cycling at the age of 39. TeamWILD, one of the organizations she created, played a crucial role in my journey, and it...
Source: Scott's Diabetes Blog - December 10, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs