The Inflammasome as a Target for the Next Generation of Anti-Inflammatory Therapies
With advancing age, a wide range of mechanisms act to provoke the immune system into a state of constant inflammatory signaling and activation. Age-related mitochondrial dysfunction leads to mislocalized mitochondrial DNA fragments that trigger the cGAS-STING pathway to provoke inflammation. Senescent cells produce pro-inflammatory signaling, and their numbers increase with age. Visceral fat tissue produces signaling similar that resulting from infected cells. The increased presence of protein aggregates aggravates immune cells inside and outside of the brain. And so forth. Given all of this, actually fixing the issue of a...
Source: Fight Aging! - January 17, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Uses of AI in Healthcare – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 17, 2024 Category: Information Technology Authors: John Lynn Tags: Administration AI/Machine Learning Ambulatory C-Suite Leadership Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC 2024 Health IT Predictions 2bPrecise Alexander Nazem Anish Sebastian Arascia Arun Nagdev Source Type: blogs

Research Organism Superheroes: Fruit Flies
Credit: iStock. Those pesky little bugs flying around the overripe bananas in your kitchen may hold the key to understanding something new about how our bodies work. That’s right, the fruit fly (Drosophila melanogaster) is a widely used research organism in genetics because of its superpower of reproducing quickly with similar genes to people. Researchers have been studying fruit flies for over a century for many reasons. First, they’re easy to please—just keep them at room temperature and feed them corn meal, sugar, and yeast (or those bananas on your counter!). Second, they reproduce more quickly and have shor...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - January 17, 2024 Category: Research Authors: Chrissa Chverchko Tags: STEM Education Tools and Techniques Cool Creatures Research Organisms Source Type: blogs

knownwell Raises $20M Series A From A16Z to Scale the First Patient-Centered Healthcare Home For Those With Overweight and Obesity
Building on This Mission, the Company is Launching an Adolescent Metabolic Health Program to Combat Rising Child Obesity Rates knownwell, an in-person and virtual, weight-inclusive primary care and metabolic health company, today announced that it has raised a $20 million Series A funding round led by a16z with participation from existing investors including Flare Capital Partners. This brings knownwell’s total funding to $24.5 million and highlights a growing demand for weight-inclusive care companies focusing on whole-person treatment approaches to obesity beyond just short-term approaches like GLP-1 utilization organi...
Source: EMR and HIPAA - January 15, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT a16z Brooke Boyarsky Pratt Dr. Angela Fitch Flare Capital Partners Health IT Funding Health IT Fundings Health IT Investment knownwell Vineeta Agarwala Source Type: blogs

Noisy, low amplitude ECG in a patient with chest pain
Written by Colin Jenkins. Colin is an emergency medicine resident beginning his critical care fellowship in the summer with a strong interest in the role of ECG in critical care and OMI. Edits by Willy Frick.A patient in their 40s with type 1 diabetes mellitus and hyperlipidemia presented to the emergency department with 5 days of “flu-like” illness. They had difficulty describing their symptoms, but complained of severe weakness, nausea, vomiting, headache, and chest pain. They denied fever, cough, dyspnea, and sick contacts. They described the chest pain as severe, crushing, and non-radiating. It was not wo...
Source: Dr. Smith's ECG Blog - January 15, 2024 Category: Cardiology Authors: Willy Frick Source Type: blogs

Bonus Features – January 14, 2024 – Epic Research shows telehealth results in more follow-up visits that in-office care, Elevance Health to offer smartphones to qualified Medicaid beneficiaries, plus 21 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies Follow-up rates for telehealth and in-office visits have remained consistent since 2020, according to analysis from Epic Research. That said, telehealth visits are more likely to result in follow-ups at the 7-, ...
Source: EMR and HIPAA - January 14, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Ambulatory Health IT Company Healthcare IT Hospital - Health System LTPAC Abbott Alliance for Pediatric Device Innovation American Telemedicine Association Atropos Health Butterfly Network Caregility Cedar Gate Technologies Childre Source Type: blogs

CoachCare Acquires Verustat
Fourth Acquisition Bolsters Remote Patient Monitoring Company’s Presence in Primary Care and Cardiology CoachCare, a leading remote patient monitoring (RPM) and virtual health company, has acquired Nashville, Tennessee-based RPM company Verustat, for an undisclosed amount. The acquisition represents CoachCare’s fourth acquisition in 12 months. Founded in 2020, Verustat brings a valuable roster of RPM clients focused on primary care and cardiology. This adds to CoachCare’s leadership position by supporting the most prevalent chronic conditions, such as hypertension, obesity, and diabetes. One of the fastest growing di...
Source: EMR and HIPAA - January 12, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT CoachCare Health IT Acquisitions Healthcare M&A Hughey Business Law pH Partners Verustat Wes Haydon Whitman Breed Abbott & Morgan Source Type: blogs

Consider Bypassing Your Health Insurance to Afford Certain Type 1 Diabetes-Related Medicines and Supplies
Since it ' s January (a new year), and about half of all Americans with employer-sponsored healthcare insurance plans have some deductibles to satisfy before their healthcare insurance really kicks-in to cover much of anything and deductibles reset on January 1, I thought perhaps this might be a good time to write about my own experience with high-deductible insurance plans and some intelligent work-arounds which I ' ve discovered to deal with those. Who knows? You might (as I did) find you actually like using a particular brand or variety of insulin which is not " preferred " by your insurance ' s PBM, or maybe you f...
Source: Scott's Web Log - January 11, 2024 Category: Endocrinology Tags: type 1 diabetes 2024 bypass insurance manufacturer coupons PBM ' PBMs unbranded insulin Source Type: blogs

Withings Scales Put Data Daily at the Center of Patient Engagement
Few people want to think about their health all the time, but many of us step on a scale every morning. Antoine Robiliard, vice president of Withings Health Solutions, explores the tensions of this interaction and the potential for making positive changes in patient lives in this video. Withings’s scales measure much more than weight: some can also report BMI, body composition, and electrochemical skin conductance, which helps diagnose the neuropathies and foot ulcers that are common in people with diabetes. The Body Pro includes a cellular connection so that it can be used by people who lack WiFi connections and mob...
Source: EMR and HIPAA - January 11, 2024 Category: Information Technology Authors: Andy Oram Tags: Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Antoine Robiliard Body Pro Body Pro 2 Connected Scales diabetes Diabetic Monitoring FDA Hea Source Type: blogs

How Can the Immune System Go Awry?
This post is part of a miniseries on the immune system. Be sure to check out the other posts in this series that you may have missed. The immune system is designed to closely monitor the body for signs of intruders that may cause infection. But what happens if it malfunctions? Overactive and underactive immune systems can both have negative effects on your health. Autoimmune Disorders To effectively monitor the body for pathogens, the adaptive immune system has to learn what a pathogen “looks like” on a molecular level. During their development, white blood cells go through training to learn how to differe...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - January 8, 2024 Category: Research Authors: Chrissa Chverchko Tags: Cells Injury and Illness Diseases Immunology Miniseries Infectious Diseases Microbes Sepsis Source Type: blogs

Fight Aging! Newsletter, January 8th 2024
This study examined whether the local injection of the supernatant of activated PRP (saPRP) into the salivary gland (SG) could help prevent aging-induced SG dysfunction and explored the mechanisms responsible for the protective effects on the SG hypofunction. Human salivary gland epithelial cells (hSGEC) were treated with saPRP or PRP after senescence through irradiation. The significant proliferation of hSGEC was observed in saPRP treated group compared to irradiation only group and irradiation + PRP group. Cellular senescence, apoptosis, and inflammation were significantly reduced in the saPRP group. Th...
Source: Fight Aging! - January 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Beyond the headlines: the truth about weight loss drugs [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! We sit down with David Ahn, an endocrinologist. Join us as we delve into the impact of weight-loss drugs, the role of incretin medications, and their potential to reshape our approach to obesity and overall health. David Ahn is an endocrinologist and chief of diabetes Read more… Beyond the headlines: the truth about weight loss drugs [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 7, 2024 Category: General Medicine Authors: Tags: Podcast Diabetes Endocrinology Source Type: blogs

Value Based Care – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 5, 2024 Category: Information Technology Authors: John Lynn Tags: Administration Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations Revenue Cycle Management 2024 Health IT Predictions 9amHealth Andreessen Horowitz Anthony Hudson Anton Kittleberger Source Type: blogs

Three normal high sensitivity troponins over 4 hours with a " normal ECG "
Written byWilly FrickA 46 year old man with a history of type 2 diabetes mellitus presented to urgent care with complaint of " chest burning. " The documentation does not describe any additional details of the history. The following ECG was obtained.ECG 1What do you think?The ECG shows sinus bradycardia but is otherwise normal. There is TWI in lead III, but this can be seen in normal ECGs. No labs were obtained. The patient was given a prescription for albuterol and a referral to cardiology.Smith comment:No patient over 25 years of age with unexplained chest burning should be discharged without a troponin rule out, no matt...
Source: Dr. Smith's ECG Blog - January 5, 2024 Category: Cardiology Authors: Willy Frick Source Type: blogs

Deconstructing diabetes stigma: A panel discussion
In conclusion, the discussion was an enriching and eye-opening event, bringing together passionate individuals dedicated to challenging the stigma around diabetes. By amplifying our voices and working together, we can make a lasting impact on the lives of those touched by diabetes.Visit enddiabetesstigma.org and become a part of the movement for change. If you’d like to get involved in spreading more awareness about this, reach out to Dennis and/or leave a comment here.  Full transcript and show notes ...
Source: Scott's Diabetes Blog - January 4, 2024 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs