Fight Aging! Newsletter, September 25th 2023
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
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Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug
https://www.fightaging.org/archives/2023/09/results-from-human-clinical-trials-do-not-support-metformin-as-a-longevity-drug/
The SENS Research Fou...
Source: Fight Aging! - September 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug
The SENS Research Foundation staff have carried out the public service of extensively discussing and dismantling the evidence commonly cited in support of metformin as a way to modestly slow aging, showing that said evidence is problematic, to say the least. Metformin might make life modestly better for diabetics, but it doesn't slow aging. This view of the human data matches the poor quality of the animal model data, in which metformin makes a poor showing in comparison to the robust data for a modest slowing of aging that is produced by the use of, say, mTOR inhibitors, or the practice of calorie restriction.
Rega...
Source: Fight Aging! - September 21, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
How Could Digital Technology Make An Impact On Primary Care?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail how primary care should be carried out in the future!
Digital health should become an organic part of primary care in the future
I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions by optimising my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests....
Source: The Medical Futurist - September 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research Healthcare Innovation technology wearables GP primary care general practitioner Source Type: blogs
Abbott Acquires Bigfoot Biomedical. Unity has a new home. Some Bigfoot employees might not like it.
In mid-September 2023, the medical technology startup known as Bigfoot Biomedical, reached a definitive agreement to be acquired by Abbott Laboratories (see the official press release athttps://www.prnewswire.com/news-releases/abbott-to-acquire-bigfoot-biomedical-furthering-efforts-to-develop-personalized-connected-solutions-for-people-with-diabetes-301918254.html for details). Financial terms of the deal were not disclosed. Bigfoot ' s CEO Was Fired from JDRFSome people with diabetes might recall that Bigfoot Biomedical was co-founded by Jeffrey Brewer, whose previous job was as CEO of the JDRF. But Mr. Brewer was sh...
Source: Scott's Web Log - September 20, 2023 Category: Endocrinology Tags: 2023 Abbott Bigfoot Biomedical Bigfoot Unity Dexcom FTC Source Type: blogs
Cells Release Insulin in Response to Music
Researchers at ETH Zurich have developed an insulin delivery system that relies on music as a trigger. The unusual technology is based on calcium ion channels that typically reside in the cell membrane. Such channels are sensitive to mechanical deformation and these researchers discovered that sound waves will activate the channels. When insulin-producing cells are genetically modified to express this channel, they will experience an influx in calcium ions when music is played close by, prompting them to release insulin. The concept could be useful as a treatment for diabetes, whereby such cells, housed in a specialized ca...
Source: Medgadget - September 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine diabetes ETH Zurich Source Type: blogs
Glooko Solicitation: What's in it for me?
This morning, I received a peculiar email. The email was from my endocrinologist ' s office (well, sort of, it was actually sent fromGlooko). The subject line said " New York Presbyterian Medical Group created a Glooko account for your diabetes data " . I was actually a little creeped-out by it, but because I had a very vague idea of what Glooko actually was, I did not instantly delete it. Still, I have no connection to Glooko (in fact, I have never once given the company my email address, nor have I ever asked them for more information, which means they attained it from my endocrinologist ' s office).Some of the issu...
Source: Scott's Web Log - September 19, 2023 Category: Endocrinology Tags: 2023 Glooko solicitation Source Type: blogs
The Best Dieting Strategy For People With Type 2 Diabetes
This diet is a very effective weight loss strategy for diabetic patients and those with prediabetes. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 19, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Weight Loss Source Type: blogs
Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mitochondrial Epigenetics in Age-Related Mitochondrial Dysfunction
The hundreds of mitochondria present in every cell in the body undertake the essential duty of producing chemical energy store molecules, adenosine triphosphate (ATP), used to power the cell. With age, mitochondria become less efficient and more damaged, generating oxidative stress and triggering inflammation while producing less ATP than is optimal. This is thought to be a major contribution to degenerative aging, though as for all contributions to aging, it requires a highly targeted way to improve mitochondrial function in order to determine just how important it is. That highly targeted therapy doesn't yet exist in a u...
Source: Fight Aging! - September 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A 60-year-old diabetic with chest pain, cath lab activated
Conclusion: It literally took me no more thanseconds to recognize APTA in today ' s tracing because:i) I saw anormal-lookinglead I —despite bizarre deflections elsewhere; —ii) Withmaximal artifact inleads II,III,aVF— and abouthalf that artifact amount inaVR,aVL; —and,iii) Alesser amount of artifact in each of the chest leads. (Source: Dr. Smith's ECG Blog)
Source: Dr. Smith's ECG Blog - September 15, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
Benefits of Calorie Restriction on Pancreatic Beta Cells
Researchers have studied calorie restriction as a means to slow aging quite extensively, but organisms are highly complex and there is always more that can be investigated. Here, researchers look in detail at the effects of calorie restriction in mice on the beta cells of the pancreas, necessary for the normal function of insulin metabolism. It is interesting to see mitophagy reduction as a means of increased mitochondrial function, though this could indicate that calorie restriction adjusts mitochondrial activity in ways that extend the functional life span of an individual mitochondrion, thereby less need for mitophagy. ...
Source: Fight Aging! - September 14, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What's new in midwifery - 13th September 2023 - Research
First, some original research that it might be useful to know about:Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix: The TOPS Randomized Clinical Trial. Effectiveness and Costs of Molecular Screening and Treatment for Bacterial Vaginosis to Prevent Preterm Birth: The AuTop Randomized Clinical Trial. Group vs Individual Prenatal Care and Gestational Diabetes Outcomes: A Secondary Analysis of a Randomized Clinical Trial. Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia: Post-hoc analysis ...
Source: Browsing - September 14, 2023 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Ignoring High Blood Pressure After 60? Study Warns of a 42% Increase in Dementia Risk
Conclusion
The study brings to light startling data: untreated high blood pressure in people over 60 raises their risk of dementia by 42%.
It’s a finding that shouldn’t be ignored, considering the societal burden dementia poses.
Even when compared to individuals with treated hypertension, the risks remain elevated.
In essence, this compelling study highlights the critical need for treating high blood pressure in later life.
Doing so could significantly lower the risk of dementia, providing not just longer but also higher-quality lives for older adults.
Read next: High Blood Pressure In Your...
Source: The EMT Spot - September 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Navigating chronic diseases and menopause: healthier habits for aging
An excerpt from The Menopause Menu. Whether it’s heart disease or cognitive decline, arthritis or diabetes, getting older is linked to an increased incidence of many different chronic diseases. The menopausal journey adds an extra layer of health risks to some of them but is also an opportunity to fine-tune healthy living goals in a
Read more…
Navigating chronic diseases and menopause: healthier habits for aging originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 12, 2023 Category: General Medicine Authors: Susan J. Baumgaertel, MD Tags: Conditions OB/GYN Rheumatology Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
