Intermittent abdominal pressure ventilation in management of neuromuscular diseases: a Delphi panel consensus
Conclusions: This is the first expert consensus on IAPV. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Annunziata, A., Simioli, F., Marotta, A., Coppola, A., Cauteruccio, R., De Simone, F., Pierucci, P., Banfi, P., Bach, J. R., Fiorentino, G. Tags: Noninvasive ventilatory support Source Type: research

Body mass index and COVID-19 disease; patient characteristics, complications and outcome.
Conclusion: body mass index is a major contributing factor for the outcome in patients with COVID-19 infection and patients with the extremes of body mass index was associated with the worst prognosis. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Kabil, A., Atef, M., Abdelmoez, H. Tags: Respiratory infections and bronchiectasis Source Type: research

Retrospective analysis of the management of pelvic decubitus ulcers and their outcomes
CONCLUSIONS: Among patients with decubitus-related osteomyelitis who did not undergo myocutaneous flapping, outcomes were generally poor regardless of treatment, and not significantly improved with prolonged antibiotics. Prospective studies are needed to assess best practice strategies for this challenging patient population.PMID:37693861 | PMC:PMC10483971 | DOI:10.1177/20499361231196664 (Source: Adv Data)
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Laura Damioli Zachary Shepard Melissa P Wilson Kristine M Erlandson Source Type: research

Retrospective analysis of the management of pelvic decubitus ulcers and their outcomes
CONCLUSIONS: Among patients with decubitus-related osteomyelitis who did not undergo myocutaneous flapping, outcomes were generally poor regardless of treatment, and not significantly improved with prolonged antibiotics. Prospective studies are needed to assess best practice strategies for this challenging patient population.PMID:37693861 | PMC:PMC10483971 | DOI:10.1177/20499361231196664 (Source: Adv Data)
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Laura Damioli Zachary Shepard Melissa P Wilson Kristine M Erlandson Source Type: research

A mesophilic phosphotriesterase-like lactonase SHOWS high stability and proficiency as quorum quenching enzyme
Chem Biol Interact. 2023 Aug 11:110657. doi: 10.1016/j.cbi.2023.110657. Online ahead of print.ABSTRACTThe problem of biofilm formation is a serious concern under various pathological conditions such as extensive burns, wounds in diabetic patients, bedsores, cystic fibrosis, nosocomial infections from implantable medical devices such as catheters, valves, etc. Environmental diffusion of biofilm (in pools, wet floors, industrial food plants) that could represent a reservoir of antibiotic resistant bacteria constitues an additional issue. In this work is described a lactonase from Rhodococcus erythropolis, a phosphotriesteras...
Source: Chemico-Biological Interactions - August 13, 2023 Category: Molecular Biology Authors: Maria Marone Elena Porzio Eros Antonio Lampitella Giuseppe Manco Source Type: research

Homoeopathic Treatment of Postnatal Stage IV Pressure Ulcer: A Case Report
Homœopathic Links DOI: 10.1055/s-0043-1770692Pressure ulcer or decubitus ulcer is generally caused due to constant pressure on the dependent parts of the body owing to impaired blood circulation. Due to this condition, the affected area shows varying changes from disruption of normal skin texture to formation of ulcer, many a times with discharge. Very commonly seen in cases with restricted ambulatory functions and /or immunodeficiency, pressure ulcers become a nuisance if left unattended.A case of a 28-year-old female patient presented with stage IV decubitus ulcer on her right gluteus since the delivery of her 6 month o...
Source: Homoeopathic Links - August 8, 2023 Category: Complementary Medicine Authors: Singh, Namrata Das, Kapil Tags: Case Report Source Type: research

Delirium and subsyndromal delirium in the intensive care unit: In-hospital outcomes and prognosis at discharge
CONCLUSIONS: The SSD group presented an intermediate prognosis between no delirium and delirium groups. It is advisable to promote its diagnosis for better risk classification.PMID:37516584 | DOI:10.1016/j.medcli.2023.05.012 (Source: Medicina Clinica)
Source: Medicina Clinica - July 29, 2023 Category: General Medicine Authors: M Durlach M Khoury C L Donato E A P érez N H Iezzi R L ópez G L Echavarr ía Source Type: research

COVID-19 and Hospital-Acquired Pressure Injuries: A Systematic Review
CONCLUSIONS: This review identified that HAPI incidence was high among men who were COVID-19 positive, had longer hospital stays, experienced prone positioning, and had care teams without a skin and wound care expert. Future research should use more robust methodology and focus on quantitative modeling to iteratively improve inpatient HAPI guidelines.PMID:37471447 | DOI:10.1097/ASW.0000000000000005 (Source: Adv Data)
Source: Adv Data - July 20, 2023 Category: Epidemiology Authors: Adrienn N Bourkas Michele Zaman R Gary Sibbald Source Type: research

A Wireless and Wearable Body-Pressure-Monitoring System for the Prevention of Pressure-Induced Skin Injuries
This article presents a wireless and wearable body-pressure-monitoring system for the on-site, real-time prevention of pressure injuries for immobilized patients. For the prevention of pressure-induced skin injuries, a wearable pressure sensor system is designed to monitor the pressure at multiple sites on the skin and to alert the danger of prolonged application of pressure on the skin with a pressure-time integral (PTI) algorithm. The wearable sensor unit is developed using a pressure sensor based on a liquid metal microchannel and integrated with a flexible printed circuit board that includes a thermistor-type temperatu...
Source: IEEE Transactions on Biomedical Circuits and Systems - June 27, 2023 Category: Biomedical Engineering Source Type: research

Negative pressure wound therapy for treating pressure ulcers
CONCLUSIONS: The efficacy, safety, and acceptability of NPWT in treating pressure ulcers compared to usual care are uncertain due to the lack of key data on complete wound healing, adverse events, time to complete healing, and cost-effectiveness. Compared with usual care, using NPWT may speed up the reduction of pressure ulcer size and severity of pressure ulcer, reduce pain, and dressing change times. Still, trials were small, poorly described, had short follow-up times, and with a high risk of bias; any conclusions drawn from the current evidence should be interpreted with considerable caution. In the future, high-quali...
Source: Cochrane Database of Systematic Reviews - May 26, 2023 Category: General Medicine Authors: Jiyuan Shi Ya Gao Jinhui Tian Jiang Li Jianguo Xu Fan Mei Zheng Li Source Type: research

Negative pressure wound therapy for treating pressure ulcers
CONCLUSIONS: The efficacy, safety, and acceptability of NPWT in treating pressure ulcers compared to usual care are uncertain due to the lack of key data on complete wound healing, adverse events, time to complete healing, and cost-effectiveness. Compared with usual care, using NPWT may speed up the reduction of pressure ulcer size and severity of pressure ulcer, reduce pain, and dressing change times. Still, trials were small, poorly described, had short follow-up times, and with a high risk of bias; any conclusions drawn from the current evidence should be interpreted with considerable caution. In the future, high-quali...
Source: Cochrane Database of Systematic Reviews - May 26, 2023 Category: General Medicine Authors: Jiyuan Shi Ya Gao Jinhui Tian Jiang Li Jianguo Xu Fan Mei Zheng Li Source Type: research

Negative pressure wound therapy for treating pressure ulcers
CONCLUSIONS: The efficacy, safety, and acceptability of NPWT in treating pressure ulcers compared to usual care are uncertain due to the lack of key data on complete wound healing, adverse events, time to complete healing, and cost-effectiveness. Compared with usual care, using NPWT may speed up the reduction of pressure ulcer size and severity of pressure ulcer, reduce pain, and dressing change times. Still, trials were small, poorly described, had short follow-up times, and with a high risk of bias; any conclusions drawn from the current evidence should be interpreted with considerable caution. In the future, high-quali...
Source: Cochrane Database of Systematic Reviews - May 26, 2023 Category: General Medicine Authors: Jiyuan Shi Ya Gao Jinhui Tian Jiang Li Jianguo Xu Fan Mei Zheng Li Source Type: research

Radio Immune Assay (RIA) Enabled Total Triiodothyronine (TT3) and Total Thyroxine (TT4) in Canine Trypanosomiasis: First Case Report from Maharashtra (India)
Iran J Parasitol. 2023 Jan-Mar;18(1):107-112. doi: 10.18502/ijpa.v18i1.12387.ABSTRACTRadio Immune Assay (RIA) is an extremely sensitive in vitro assay technique to measure concentrations of antigen viz. hormones in biological fluids using antibodies. The present study reports the status of total triiodothyronine (TT3) and total thyroxine (TT4) in Trypanosoma evansi infection in a dog, year 2022. An adult, non-descript, male dog was referred to the Department of Veterinary Nuclear Medicine, Mumbai Veterinary College, (MAFSU), Parel, Mumbai (India) with a history of inappetence, weakness, and ataxia of the hind limbs. Inspec...
Source: Iranian Journal of Parasitology - May 17, 2023 Category: Parasitology Authors: Pragati Salutgi Chandrakant Galdhar Riddhi Sonigra Kaustubh Natu Neha Mumbarkar Saloni Mathkar Arundhati Dalvie Rajiv Gaikwad Source Type: research