Ankylosing Spondylitis: MRI
DiscussionAnkylosing spondylitis (also known as Bechterew disease and Marie Str ümpell disease). More common in males with 3:1 ratio.Spondyloarthritis is a group of diseases with common clinical, laboratory, and genetic features& association with human leukocyte antigen HLA-B27. Ankylosing spondylitis is the prototypic disease in the spectrum of spondyloarthritis which usually has axial skeletal manifestations. Other representative disorders in this spectrum of disease which usually have peripheral articular involvement, but axial skeleton manifestations are also frequently seen are --psoriati...
Source: Sumer's Radiology Site - January 11, 2019 Category: Radiology Authors: Sumer Sethi Source Type: blogs
LESS BAD is not necessarily GOOD
One of the reasons why the Wheat Belly lifestyle is so spectacularly effective for restoring health, losing weight, and turning back the clock a decade or two is because we reject the flawed logic of conventional nutritional advice.
There is a long list of reasons why conventional nutritional advice gets it so wrong, from logical blunders, to relying on flawed observational evidence (rather than clinical trials), to getting too cozy with Big Food companies like Coca Cola and Kraft.
Let’s discuss a common and widely-held blunder in logic that is applied over and over again in nutrition:
If something bad is replaced by...
Source: Wheat Belly Blog - January 8, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates gluten-free grain-free grains undoctored wheat belly Source Type: blogs
Ultrasound Case 040
A 22 year old man presents with abdominal pain and diarrhoea. He has 3 months of intermittent diarrhoea sometimes with blood, accompanied with weight loss and abdominal discomfort.
The post Ultrasound Case 040 appeared first on Life in the Fast Lane. (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - December 31, 2018 Category: Emergency Medicine Authors: Dr James Rippey Tags: Gastroenterology TOP 100 Ultrasound Bowel ultrasound Crohn's disease Inflammatory bowel disease Source Type: blogs
Fight Aging! Newsletter, November 5th 2018
In conclusion, weight cycling significantly increased life-span relative to remaining with obesity and had a similar benefit to sustained modest weight loss.
Support for Oxidized Cholesterol as a Primary Cause of Atherosclerosis
https://www.fightaging.org/archives/2018/11/support-for-oxidized-cholesterol-as-a-primary-cause-of-atherosclerosis/
In the paper I'll point out today, the authors provide evidence in support of the concept that it is specifically oxidized cholesterol that is the primary cause of atherosclerosis rather than the condition resulting from too much cholesterol in general. In atherosc...
Source: Fight Aging! - November 4, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Demonstration of Regeneration Achieved Using Extracellular Vesicles from Stem Cells
Most present stem cell therapies achieve their positive results through signaling rather than any other action of the transplanted cells. The transplanted cells die fairly rapidly, but their signals change the behavior of native cells for the better for some period of time. Most cell signals are delivered via some form of extracellular vesicle, small membrane-bound packages containing a wide variety of molecules. The contents and variety of vesicles are at this time very poorly cataloged, but it is still possible to make use of them. Vesicles can be harvested from cultured cell populations, and packaging such vesicles as a...
Source: Fight Aging! - October 29, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
“Smart” Training Devices Alleviate Concerns of Self-Injection: Interview with Noble International’s Joe Reynolds
Most patients encounter shots and injections, like the flu vaccine, in the context of a clinic or local pharmacy. However, for many patients, shots and injections are not an annual occurrence but are required frequently and, as a result, need to be self-administered at home. Biologic drugs have recently found success addressing chronic diseases but can require at-home administration using prefilled syringes (PFSs) and autoinjectors.
Patients using these self-injection devices can experience psychological challenges ranging from mild squeamishness to extreme anxiety. A recent study of patients with rheumatoid arthritis and...
Source: Medgadget - May 3, 2018 Category: Medical Devices Authors: Michael Batista Tags: Exclusive Medicine Pediatrics Source Type: blogs
No Microbiome Santa Claus we cannot magically convert correlative studies into causal ones. And scientists dishing out medical advice about vaping based on such bad science is ridiculous.
Conclusions. In summary, we found that tobacco smokingsignificantly alters the bacterial profiles in feces, buccal, and saliva samples.Nooooooooooooooooo. Nooooooo. No.So - you might ask -- why does this matter? This is just a little bit of a word choice issue right? Wrong. The press release and the paper mislead as to what was found here. You might then say "so what - what does it matter?". Well, it does matter because when you make these types of misleading statements they might get picked up by the press or the public. Like in the examples below:Daily Mail:An incentive to switch to e-cigare...
Source: The Tree of Life - April 30, 2018 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs
Fight Aging! Newsletter, April 30th 2018
In conclusion, in the Framingham Heart Study population, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated.
Recent Research on the Benefits of Exercise in Later Life
https://www.fightaging.org/archives/2018/04/recent-research-on-the-benefits-of-exercise-in-later-life/
A sizable body of work points to the ability of older individuals to continue to obtain benefits through regular physical activity, and particularly in the case...
Source: Fight Aging! - April 29, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cornelis (Cees) Wortel, Ichor Therapeutics Chief Medical Officer, on Rejuvenation Research and Its Engagement with the Established Regulatory System
Ichor Therapeutics is the most mature of the US-based companies that have emerged from the SENS rejuvenation research community in recent years. You might recall a number of interviews back in the Fight Aging! Archives with founder and CEO Kelsey Moody. He has his own take on how our community should proceed from laboratory to clinic: he is very much in favor of demonstrating (a) that the formal regulatory path offered by the FDA can work for the treatment of aging, and (b) that - given the right strategic approach - rejuvenation therapies can attract the attention, collaboration, and backing of Big Pharma entities in the ...
Source: Fight Aging! - April 23, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
How much can what we eat help inflammatory bowel disease?
Speaking at the event, Dr Alan Desmond, Consultant Gastroenterologist at South Devon Healthcare NHS Foundation Trust, UK, suggested that active Crohn’s Disease (CD) can be successfully reversed by adopting a Whole Food Plant Based Diet (WFPBD).
He cited data from two trials which have shown diets like the WFPBD, which restricts animal protein, animal fat, omega-6 PUFAs, dairy, emulsifiers and food additives while providing dietary fibre can bring improvements in people with Crohn’s in just six weeks.
Patients in the trials obtained 50% of caloric intake from an enteral formula (an artificial ‘complete nutrition...
Source: Nursing Comments - March 13, 2018 Category: Nursing Authors: M1gu3l Tags: Nutrition Source Type: blogs
Medical education systematically ignores the diversity of medical practice
I remember the moment I first saw a female chest X-ray. It was my own. My lecturers in the first months of medical school showed a few chest films, but I failed to recognize that the bodies all looked the same. I proudly showed my sister my clear lungs. She laughed and said, “I can see your boobs.” I looked again at mine with new eyes, taking in the dull, gray color of adipose tissue that I had never seen before. Something was missing from all the previous images I had seen: diversity.
As second years, we practiced procedures on each other to gain experience before working with patients. We did abdominal ultras...
Source: Kevin, M.D. - Medical Weblog - January 30, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/rebekah-fenton" rel="tag" > Rebekah Fenton, MD < /a > Tags: Education Hospital-Based Medicine Pediatrics Primary Care Source Type: blogs
MKSAP: 22-year-old woman is evaluated for a flare of Crohn disease
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 22-year-old woman is evaluated for a flare of Crohn disease. A colonoscopy performed 6 months ago showed moderate, patchy, left-sided colitis extending from the descending colon to the splenic flexure. She responded to therapy with prednisone but declined maintenance therapy in advance of conceiving. She is now 12 weeks pregnant and for the past 2 weeks has experienced bloody diarrhea and left-sided abdominal pain.
On physical examination, temperature is 37.2 °C (99.0 °F), blood pressure is 110/66 mm Hg, and...
Source: Kevin, M.D. - Medical Weblog - December 9, 2017 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology OB/GYN Source Type: blogs
FDA Approves Sixth United States Biosimilar
Recently, the FDA announced that it approved Boehringer Ingelheim’s Cyltezo (adalimumab-adbm), the second biosimilar to AbbVie’s blockbuster Humira and sixth biosimilar in the United States. “Cyltezo is the first biosimilar from Boehringer Ingelheim to be approved by the FDA and marks an important step towards our goal of providing new and more affordable treatment options to healthcare providers and patients,” said Ivan Blanarik, Senior Vice President and Head of Therapeutic Area Biosimilars at Boehringer Ingelheim. “Chronic inflammatory diseases collectively affect 23.5 million people in the U.S., and Cyltezo h...
Source: Policy and Medicine - November 17, 2017 Category: American Health Authors: Thomas Sullivan - Policy & Medicine Writing Staff Source Type: blogs
MR Enterography : Crohn's Disease
Case Report : Young adult male known case of crohns disease on chemotherapy , suggests on MR enterogram (on oral mannitol and Intravenous Gadolinium) ,subtle narrowing (less than 5 cms) , increased wall thickness (5-7mm) , ulceration, hypoperistalsis, irregularity of terminal ileum including ileocecal junction& mesentric vessels prominence, sub centimeter lymph nodes with similar findings in distal colon including descending colon, rectum (prominent vasa recta), with no obstructed loops or creeping fat sign or pericolic abscess/ fistula etcTeaching pointsBy Dr MGK Murthy, &nbs...
Source: Sumer's Radiology Site - October 2, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Leaky gut: What is it, and what does it mean for you?
Before the medical community had better understanding of the mechanisms that cause disease, doctors believed certain ailments could originate from imbalances in the stomach. This was called hypochondriasis. (In Ancient Greek, hypochondrium refers to the upper part of the abdomen, the region between the breastbone and the navel.) This concept was rejected as science evolved and, for example, we could look under a microscope and see bacteria, parasites, and viruses. The meaning of the term changed, and for many years doctors used the word “hypochondriac” to describe a person who has a persistent, often inexplicable fear ...
Source: Harvard Health Blog - September 22, 2017 Category: Consumer Health News Authors: Marcelo Campos, MD Tags: Digestive Disorders Health Source Type: blogs
