LESS BAD is not necessarily GOOD

One of the reasons why the Wheat Belly lifestyle is so spectacularly effective for restoring health, losing weight, and turning back the clock a decade or two is because we reject the flawed logic of conventional nutritional advice. There is a long list of reasons why conventional nutritional advice gets it so wrong, from logical blunders, to relying on flawed observational evidence (rather than clinical trials), to getting too cozy with Big Food companies like Coca Cola and Kraft. Let’s discuss a common and widely-held blunder in logic that is applied over and over again in nutrition: If something bad is replaced by something less bad and there is an apparent health benefit, then a lot of the less bad thing must therefore be good. With wheat, if we replace something bad—white flour products—with something less bad—whole grain products—and there is less obesity, type 2 diabetes, heart disease, and colon cancer (there is indeed a modest reduction), then a whole bunch of whole grains must therefore be good. Let’s apply this to one of my perennial favorites, cigarettes: If we replace full-tar, unfiltered cigarettes—bad—with low-tar, filtered cigarettes—less bad—that yields a modest reduction in heart attack and lung cancer, then, by the logic of nutrition, you should smoke a lot of low-tar, filtered cigarettes. This is absurd, of course, but illustrates this blunder in logic that can lead you to false conclusions. If we...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates gluten-free grain-free grains undoctored wheat belly Source Type: blogs

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Publication date: Available online 16 February 2019Source: European Journal of RadiologyAuthor(s): Lequn Zhu, Zheng Xu, Guanwu Li, Ying Wang, Xuefeng Li, Xiao Shi, Haiyang Lin, Shixin ChangAbstractBackgroundMarrow fat accumulates in diabetic conditions but remains elusive. The published works on the relationships between marrow fat phenotypes and glucose homeostasis are controversial.PurposeTo detect the association of insulin resistance with marrow adiposity in postmenopausal women with newly diagnosed type 2 diabetes (T2D) using chemical shift-encoded water–fat MRI.MethodsWe measured vertebral proton density fat fr...
Source: European Journal of Radiology - Category: Radiology Source Type: research
Publication date: February 2019Source: Best Practice &Research Clinical Obstetrics &Gynaecology, Volume 55Author(s):
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
ConclusionsWe found the precise anatomy of the connective tissue layer from umbilical artery to urinary bladder and the superior vesical artery. Our procedure based on the precise anatomy obtained in this study is reasonable anatomically as a method for separation of the vesicouterine ligament during radical hysterectomy.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
This study investigated the modulation of micro-RNAs associated with the PI3K/AKT/mTOR-axis by mango polyphenols (MP) in MCF-12A non-cancer and MDA-MB231 breast cancer cell lines. MP reduced proliferation in the cancer cells by up to 90% (10 mg GAE/L) but did not cause cytotoxicity in the non-cancer cells within the same concentration range. In contrast, in TNF-α-treated non-cancer MCF-12A cells, MP significantly decreased expression and phosphorylation of NF-κB while modulating mRNA and protein levels of PI3K/AKT/mTOR and up-regulated miR-126. The mechanistic involvement of miR-126 was investigated using its...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
In this study, Se-enriched peanut protein nanoparticles-stabilized Pickering emulsions (PPEs) were used to encapsulate 5DN to enhance its bioaccessibility, cellular uptake and transport rate. The preparation of PPEs, and their digestion profiles in gastrointestinal tract, cell uptake and transport were investigated. Results showed that the bioaccessibility of 5DN was significantly higher within PPEs (18.3%) than in bulk oil (9.2%). Besides, PPEs-encapsulated 5DN has a greater apical-to-basolateral (AP-BL) transport rate (26.9 × 10−6 cm s−1) than 5DN (21.7 × 10−6 cm s−1). ...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: April 2019Source: Journal of Functional Foods, Volume 55Author(s): Chia-Yuan Chang, Bing-Ying Ho, Tzu-Ming PanAbstractColorectal cancer (CRC) is a major cause of cancer-related deaths worldwide. Chemotherapy is the usual treatment, but entails side effects. Although lactic acid bacteria (LAB) ameliorate CRC, the effects of LAB-fermented skim milk are unknown. Thus, we investigated the effect of Lactobacillus paracasei subsp. paracasei NTU 101-fermented skim milk (NTU 101FM) in combination with chemotherapy on CRC, and its effect on chemotherapeutic side effects in vivo. NTU 101FM + chemotherapy treatm...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: April 2019Source: Journal of Functional Foods, Volume 55Author(s): Anna Mas-Capdevila, Lisard Iglesias-Carres, Anna Arola-Arnal, Manuel Suarez, Begoña Muguerza, Francisca I. BravoAbstractThe aim of this study was to evaluate the effect of long-term administration of the protein hydrolysate from chicken feet Hpp11 in diet-induced hypertensive rats. Rats were fed standard or cafeteria (CAF) diets for 12 weeks, and during the final 3 weeks, CAF animals were administered vehicle, Captopril or Hpp11. Systolic blood pressure (SBP) was recorded weekly. Body weight and plasmatic lipid and glucose level...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: April 2019Source: Journal of Functional Foods, Volume 55Author(s): Fernanda Torres Quitete, Egberto Gaspar de Moura, Geórgia Correa Atella, Patricia Cristina Lisboa, Elaine de OliveiraAbstractWe investigated the effects of maternal coconut oil supplementation during breastfeeding on the endocrine-metabolic profiles of offspring and the impact of continued exposure throughout life. Rat mothers were separated into: soybean oil (SO); and coconut oil (CO) groups and received the oils through gavage (0.5 g/kg of BW) and had free access to standard chow. After weaning, half of the pups from CO group co...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: April 2019Source: Journal of Functional Foods, Volume 55Author(s): Jing Li, Mei Luo, Zhen Luo, An-Yuan Guo, Xiangliang Yang, Minghua Hu, Qiong Zhang, Yanhong ZhuAbstractCyclocarya paliurus polysaccharides have been reported to prevent diabetes, but the underlying mechanisms are unclear. This current study aimed to reveal the possible underlying anti-diabetic mechanisms of CPP based on transcriptome profiling. Our experimental results demonstrated CPP could protect pancreas islets through decreasing oxidative stress and pro-inflammatory cytokines, and alleviate dyslipidemia, hepatic steatosis and liver inj...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
CONCLUSION: CXCR2, ANXA1, and CCR3 as well as olfactory receptor-related genes (proteins) may be used as biomarkers to assess zinc status in mice. PMID: 30770772 [PubMed - in process]
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
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