TWiV 919: Motivated by volatiles
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 vaccine booster composition (FDA) Settling in for the long haul (Crooked Timber) Flavivirus-induced skin volatile attracts mosquitoes (Cell) Letters read on TWiV 919 Timestamps by Jolene. Thanks! ...
Source: This Week in Virology - MP3 Edition - July 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin
In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of m...
Source: This Week in Virology - MP3 Edition - July 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 917: Boosters on, Paul Offit
Paul Offit returns to TWiV to discuss why, during the recent FDA advisory committee meeting, he voted against releasing revised COVID-19 vaccines containing an Omicron component, and the reasons why children must be vaccinated against the disease. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 28 June 2022 VRBPAC meeting materials (FDA) Don’t rush to change COVID vaccines (STAT) Materials from 28 June FDA advisory meeting (FDA) Letters read on TWiV 917 Tim...
Source: This Week in Virology - MP3 Edition - July 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin
In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation ca...
Source: This Week in Virology - MP3 Edition - July 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 915: Mouse mouth to mouse mom
TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Postdoctoral position in the Kielian Laboratory (pdf) COVID vaccine update for fall (WaPo) Don’t rush to change COVID vaccines (STAT) Materials from 28 June FDA advisory meeting (FD...
Source: This Week in Virology - MP3 Edition - July 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin
In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Age as a risk factor for severe disease (NY Times) Omicron boosters for the fall (NPR) P...
Source: This Week in Virology - MP3 Edition - July 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 913: Twinkle twinkle little SARS
TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Poliovirus in UK sewage (ProMedMail and Science) Poliovirus eradication effort (Science) Long COVID after Delta and Omicron (Lancet) How common is long COVID? (Nature) Immune enhancers as ...
Source: This Week in Virology - MP3 Edition - June 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin
In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Reinfection outcomes (Research Square) CDC recommends v...
Source: This Week in Virology - MP3 Edition - June 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: USA authorises vaccines for youngest of kids
After a long wait, the US Food and Drug Administration (FDA) and Centres for Disease Control and Prevention (CDC) have finally approved two COVID vaccines for use in children between the ages of six months and five years old. But despite a unanimous decision amongst regulators, parents still have questions about whether to vaccinate their young children, with survey data suggesting that the majority do not intend to accept vaccines right away. In this episode of Coronapod, we dig into the trials, the statistics and the regulators decision making process, in search of clarity around what the data are saying.News:&...
Source: Nature Podcast - June 24, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 911: Antibody can get vaccinated now
TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hepatitis of unknown etiology (MMWR) Clinical recognition of monkeypox (CDC) Epstein-Barr virus nanoparticle vaccine (Cell Rep Med) Minimal impact of mAb therapy on COVID vaccine induced antibodies (Sci Trans Med) L...
Source: This Week in Virology - MP3 Edition - June 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 910: COVID-19 clinical update #119 with Dr. Daniel Griffin
In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms following infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Tixagevimab-Cilgavimab for i...
Source: This Week in Virology - MP3 Edition - June 18, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talk Evidence - political persuasion and mortality, too much medicine
In this week's episode, Helen Macdonald is joined by Joseph Ross, US research editor for The BMJ, and Juan Franco, editor of BMJ EBM. They begin by discussing a review of obesity interventions in primary care, and Joe wonders if GPs are really the best people to tackle the issue. https://www.bmj.com/content/377/bmj-2021-069719 Cervical screening in the UK now includes HPV testing, and they look at research which examines wheth er this could mean longer periods between screening tests. https://www.bmj.com/content/377/bmj-2021-068776 They all enjoy a new State of the Art Review into Revascularization in stable coronary...
Source: The BMJ Podcast - June 17, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence - political persuasion and mortality, too much medicine
In this week's episode, Helen Macdonald is joined by Joseph Ross, US research editor for The BMJ, and Juan Franco, editor of BMJ EBM. They begin by discussing a review of obesity interventions in primary care, and Joe wonders if GPs are really the best people to tackle the issue. https://www.bmj.com/content/377/bmj-2021-069719 Cervical screening in the UK now includes HPV testing, and they look at research which examines whether this could mean longer periods between screening tests. https://www.bmj.com/content/377/bmj-2021-068776 They all enjoy a new State of the Art Review into Revascularization in stable coronary a...
Source: The BMJ Podcast - June 17, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Varenicline and African American Smokers, COVID-19 Vaccination in Children and Adolescents, Digital Breast Tomosynthesis vs Digital Mammography, and more
Editor's Summary by by Anne Cappola, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the June 14, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - June 14, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 908: COVID-19 clinical update #118 with Dr. Daniel Griffin
In COVID-19 clinical update #118, Dr. Griffin discusses management of hair loss after infection, FDA announcements on vaccine schedule and recommendations, Moderna announcement on bivalent booster candidate, association between vaccination and infection during pregnancy, population-level implications of Israel’s booster campaign, PAXLOVID outcomes during recent infection surge, efficacy and safety of Tixagevimab-cilgavimab, diagnostic accuracy of infection by canines, efficacy of colchicine in hospitalized patients, and factors associated with hospital readmission.   Subscribe (free): Apple Podcasts, Google Podcasts,...
Source: This Week in Virology - MP3 Edition - June 11, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts